This Is MS Multiple Sclerosis Community: Knowledge & Support

It hadn't occurred to me before that smoking might be a risk factor which could explain the increase of MS in women, (in the UK at least, women and young girls smoke far more than men and boys). I would have thought it should be fairly easy to correlate the figures. Sunlight exposure, along with the myriad other non infectious environmental conditions, will be harder to quantify.
This from PubMed:

Environmental risk factors for multiple ...

I can't help digging around in the information regarding "resetting" the immune system. I find it darned interesting. Notice who they are recruiting in this trial....
Bob

http://clinicaltrials.gov/ct/show/NCT00296205?order=5

Inclusion Criteria:

* Diagnosis of secondary progressive (SPMS), primary progressive (PPMS) or progressive relapsing (PRMS) multiple sclerosis
* A diagnosis of MS will be established by fulfilling criteria “Recommended Diagnostic Criteria for Multiple Sclerosis: Guidelines from the Internal Panel on ...

Must read very interesting stuff here.


<shortened url>

Bruce Trapp's work is viewed as cutting edge. It was his work in the late 1990s that showed that it was the damage to axons (nerve fibres) that caused disability rather than just de-myelination.

Ian



Nerve Fibres are Severed by Inflammation in MS Lesions, Leading to Permanent Disabilities

Bruce Trapp, PhD––Cleveland Clinic, Lerner Research Institute, Cleveland, Ohio

Background

Multiple sclerosis (MS) is a chronic, disabling neurodegenerative disease. It strikes most often during early adulthood, and ...

The brain discoveries continue...



Brain's white matter -- More 'talkative' than once thought

Johns Hopkins scientists have discovered to their surprise that nerves in the mammalian brain’s white matter do more than just ferry information between different brain regions, but in fact process information the way gray matter cells do.

The discovery in mouse cells, outlined in the cover story of the March issue of Nature Neuroscience, shows that brain cells “talk” with each other ...

Hey,

The brain atrophy impact seems to be a very positive element and very consistent with the previous case-study where PIO was used for a person with progressive MS. Hopefully there will be continuation on this research.

Best Regards,
Degerlache

------------------------------------------------------------------------------------

Results of a Phase I Trial of Pioglitazone in RRMS Patients

Claudia Kaiser, Dinesh Shukla, Glenn Stebbins, Demetrios Skias, George Katsamakis, Hoffman Estates, IL, Dusan Stefoski, Douglas Jeffery, Winston Salem, NC, Douglas L. Feinstein, ...

http://c.moreover.com/click/here.pl?j924214166&w=464753

Each year I attend the AAN with one of my co-workers and we write up the notes from the presentations we go to as a service to the MS community.

Here are our notes from this year.
http://msnews.acceleratedcure.org/node/2642

I had always wondered about the fatigue. Here is a pretty good article explaining MS related fatigue.

www.healthology.com/multiple-sclerosis/article1024.htm

You can find a very interesting video-presentation from the Harvard MS conference, here:
Link to the presentation

Just click on the small film icons on the left side to watch the videos.

--Frank