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A board to discuss Low Dose Naltrexone (LDN) as a treatment for Multiple Sclerosis

New LDN user for MS Secondary Progressive

Greetings all,
As mentionned I am SP since 2005. My edss score is near 6.0.
I can still walk short distances until recently. I am canadian and my doctor
completely refused to entertain prescribing LDN even when presented with
litterature aplenty. The fact it was an off-label prescription was enough for him. Afterwards I went on a 10 month quest to find a doctor who would prescribe it. My initial prescription was 1.5mg for 2 ...
Read more : New LDN user for MS Secondary Progressive | Views : 2558 | Replies : 1

LDN and Tysabri

Does anyone know of any information about taking LDN and Tysabri? I need to show my Neurologist why I think it would be okay to be on LDN and start Tysabri as well. From what i am reading about Tysabri, it doesnt affect the immune system at all, so taking LDN shouldnt be a problem, but does anyone know differently or how I can prove it?

Read more : LDN and Tysabri | Views : 3317 | Replies : 1

anyone prescribed a.m. LDN ?

Recently I filled my 4.5 mg LDN script and I began taking it a week ago today. (Yes, I realize that many, many people start out on a lower dose, and I have questioned my neuro's reasoning already. I was told- "all of his patients are using this dose." I didn't like that answer, but figured I'd try it anyway). I have been experiencing severe insomnia on and off for the past 3 months. ...
Read more : anyone prescribed a.m. LDN ? | Views : 4227 | Replies : 4

LDN and bladder issues

Just curious to hear from anyone on LDN that thinks LDN has helped their bladder issues.
Read more : LDN and bladder issues | Views : 4253 | Replies : 4

I have definitely progressed while on LDN

I have been on LDN or over 3 years and have declined significantly. I remain on it because it's cheap, benign, and who knows? Maybe it's doing me some good.

I wanted to post this loud and clear because on other posts here people are making sweeping statements like " no documented cases anywhere of anyone getting worse while on LDN" .


MY doctor has other patients who have discontinued it due to no ...
Read more : I have definitely progressed while on LDN | Views : 9838 | Replies : 31

LDN and Copaxone

Was curious to hear from MSers who are both on LDN and Copaxone. If you fit this description, how long have you been using both for your MS? Do you feel that using both together has been more beneficial? If so, how? Do you inject the Copaxone daily or less often? Does your neuro prescribe both drugs or do you get your LDN from another source? Thanks in advance for any insight you can provide ...
Read more : LDN and Copaxone | Views : 3935 | Replies : 7

New lesions after 10 months on LDN

Can anyone share with me hearing about or experiencing new lesions while on LDN? I spent 7 years on Rebif, with absolutely no new lesions and then developed neutralizing antibodies and was taken off it. After being told I needed to be "med free" I convinced my doc to allow me to try LDN. Getting it from a reputable pharmacy and taking 4.5 mgs nightly- I just had my first MRI in a year. 2 ...
Read more : New lesions after 10 months on LDN | Views : 13540 | Replies : 22

2+ months on LDN and spasticity and pain through the roof!

This is like my 3rd time trying ldn. I am on 3mg. I have been on it for over 2 months, no missed doses, and since day one the spasticity has increased 10 fold. I am already wheelchair bound 95% of the time, so this increase in spasticity has made it even harder for therapy and walking. It has also tripled my pain! Please tell me that I am not the only one on the ...
Read more : 2+ months on LDN and spasticity and pain through the roof! | Views : 3173 | Replies : 10

Does dosage have a linear relationship with side effects?

I started out at 1 mg about 3 months ago and didn't notice much of a change, except maybe a bit more weakness or spasticity. After a month, I doubled to 2 mg and am still there. Weakness and spasticity seem to be worse.

I initially filled a prescription at 4.5mg, but never took it until I worked my way up. I always thought I would get there, but now wonder if I should even ...
Read more : Does dosage have a linear relationship with side effects? | Views : 3280 | Replies : 3

Starting Dose (4.5mg)

I know it is recommended to start at 3mg or less than work up, but the tablets I ordered only came in 4.5 mg doses and I chose that over the mix-your-own solution for convenience.
I have never really experienced spasticity. I have had considerable stiffness during my last attack. I am not worried about symptoms increasing initially, I will deal with that as it comes.
My question is, will starting straight away at 4.5 ...
Read more : Starting Dose (4.5mg) | Views : 7167 | Replies : 8


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