I found this recently published article on pubMed very encouraging:
LDN Therapeutic Implications for MS
This is from a Pennsylvania State Univ study published last month.
Admittedly, the study was conducted on the EAE mouse model, but the conclusions are very encouraging and relate to treatment with either OGF or LDN (which produces high endogenous OGF levels):
1. Halted EAE disease progression
2. Reversed neurological deficits, and
3. Prevented onset of dysfunction across considerable span ...