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2018 review: vitamins & MS incidence,progression,improvement

A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis ... 0218300078

•Vitamin D has important roles in MS and can be measured as precursor, or used as treatment.
•B6, B9, and B12 deficiency can elevate serum level of homocysteine, which may lead to an inflammatory state in the CNS.
•Vitamins A, E, and B1 deficiencies are believed to play important roles ...
Read more : 2018 review: vitamins & MS incidence,progression,improvement | Views : 227 | Replies : 4



I recently heard about this dietary supplement which can help PWMS to get better. ... upplements

Has anyone tried this?

Read more : klamath | Views : 489 | Replies : 0

MitoQ: Adverse Effects

The targeted anti-oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue.
Physiol Rep. 2018 Apr;6(7):e13667.

    Kidney proximal tubules (PTs) contain a high density of mitochondria, which are required to generate ATP to power solute transport. Mitochondrial dysfunction is implicated in the pathogenesis of numerous kidney diseases. Damaged mitochondria are thought to produce excess reactive oxygen species (ROS), which can lead to oxidative stress and activation of cell death pathways. MitoQ is a mitochondrial ...
Read more : MitoQ: Adverse Effects | Views : 515 | Replies : 0

Lipoic Acid & Elevated Liver Enzymes: Anyone Else?

Hi everyone,
Kira here. I’m going to share my experience on this and ask if anyone else has experienced the same?

I started taking 1200 mg. Lipoic Acid in December when my neurologist recommended it, after he mentioned promising research results for MS.

I looked at the Clinical Trial being done at OHSU w/the VA in Portland, OR, using LA for MS, and after looking at the Adverse Events sections of that trial, asked my ...
Read more : Lipoic Acid & Elevated Liver Enzymes: Anyone Else? | Views : 517 | Replies : 5


Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation
Sci Transl Med. 2012 Jun 6;4(137):137ra73.

    Lipids constitute 70% of the myelin sheath, and autoantibodies against lipids may contribute to the demyelination that characterizes multiple sclerosis (MS). We used lipid antigen microarrays and lipid mass spectrometry to identify bona fide lipid targets of the autoimmune response in MS brain, and an animal model of MS to explore the role of the identified ...
Read more : Phosphatidylserine | Views : 461 | Replies : 3

FMT Substitute?

So I've tried a couple of rounds of David Perlmutter's 90 billion CFU probiotic. I took one capsule/day for the 30 day regimen. The effects were negligible. It occurred to me that even though this is a fairly high CFU count probiotic, that it is likely akin to the proverbial spit in a hurricane when compared to a fecal microbiota transplant (FMT). Has anyone pondered, or even tried perhaps, a much higher dose, e.g., splitting ...
Read more : FMT Substitute? | Views : 855 | Replies : 17

2018 viewpoint - disclosures in nutrition research

Disclosures in Nutrition Research
Why It Is Different ... irect=true

Nutrition research is among the most contentious fields of science. Although the totality of an individual’s diet has important effects on health, most nutrients and foods individually have ambiguously tiny (or nonexistent) effects.1 Substantial reliance on observational data for which causal inference is notoriously difficult also limits the clarifying ability of nutrition science. When the data are not ...
Read more : 2018 viewpoint - disclosures in nutrition research | Views : 610 | Replies : 0

2018 study: Serum mag inversely associated w EBV viral load

Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphoma in Uganda ... 2117302035

Epstein-Barr virus (EBV) causes endemic Burkitt lymphoma (eBL). EBV control was improved by magnesium (Mg2+) supplementation in XMEN, an X-linked genetic disease associated with Mg2+ deficiency, high circulating EBV levels (viral loads), and EBV-related lymphomas. We, therefore, investigated the relationship between Mg2+ levels and EBV levels and ...
Read more : 2018 study: Serum mag inversely associated w EBV viral load | Views : 639 | Replies : 1

2017 meta analysis: zinc and parkinson's

Association Between Serum Zinc Levels and the Risk of Parkinson’s Disease: a Meta-Analysis ... 017-0941-2

Recent studies have found that the serum zinc levels were associated with the risk of Parkinson’s disease (PD), but the results were inconsistent. Thus, we conducted a meta-analysis to summarize the evidence from observational studies between them. Pertinent studies were identified by a search in PubMed, Embase, and Web of science up to ...
Read more : 2017 meta analysis: zinc and parkinson's | Views : 623 | Replies : 0

2018 meta analysis: zinc and autoimmunity

this is close to what my thesis was *supposed* to be like
at least it got done by somebody!

Zinc Status and Autoimmunity: A Systematic Review and Meta-Analysis

Zinc is an essential trace element for living organisms and their biological processes. Zinc plays a key role in more than 300 enzymes and it is involved in cell communication, proliferation, differentiation and survival. Zinc plays also a role ...
Read more : 2018 meta analysis: zinc and autoimmunity | Views : 604 | Replies : 0


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