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Buyer Beware

So I was investigating a new supplement I saw advertised in the coupons from my Sunday paper. It's called Cognium and it's sold by Natrol. A website was given where many good things were said about it, e.g., it enhances glucose uptake in neurons, it improves cerebral blood flow, it binds to beta-amyloid and reduces clusters and tangles, it enhances cognitive and memory performance and on and on. I checked the references. Out of eight ...
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Liposome-based immunotherapy, therapeutic effect on MS

Liposome-based immunotherapy against autoimmune diseases: therapeutic effect on multiple sclerosis.
Nanomedicine (Lond). 2017 Jun;12(11):1231-1242.

    AIM: Based on the ability of apoptosis to induce immunological tolerance, liposomes were generated mimicking apoptotic cells, and they arrest autoimmunity in Type 1 diabetes. Our aim was to validate the immunotherapy in other autoimmune disease: multiple sclerosis.

    MATERIALS & METHODS: Phosphatidylserine-rich liposomes were loaded with disease-specific autoantigen. Therapeutic capability of liposomes was assessed in vitro and in vivo.

    RESULTS: Liposomes ...
Read more : Liposome-based immunotherapy, therapeutic effect on MS | Views : 198 | Replies : 0


Vitamin D increases regulatory T cells

Vitamin D modulates different IL-17-secreting T cell subsets in multiple sclerosis patients.
J Neuroimmunol. 2016 Oct 15;299:8-18.

    Vitamin D deficiency is an environmental risk factor for MS, a Th17 cell-mediated autoimmune disease that results in demyelination in the CNS. Therefore, we aimed to evaluate the ability of in vitro 1,25(OH)2D in modulating different Th17 cell subsets in MS patients in remission phase. In the present study, the production of Th17-related cytokines (IL-1β, IL-6, IL-17, IL-22), ...
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Low vitamin D linked to increased risk of cognitive decline

Vitamin D Levels and the Risk of Cognitive Decline in Chinese Elderly People:
the Chinese Longitudinal Healthy Longevity Survey.

J Gerontol A Biol Sci Med Sci. 2016 Oct;71(10):1363-8.

    BACKGROUND: Vitamin D has a neuroprotective function, potentially important for the prevention of cognitive decline. Prospective studies from Western countries support an association between lower vitamin D level and future cognitive decline in elderly people. No prospective study has examined this association in Asia.

    METHODS: This community-based ...
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Vitamin D reduces relapse rate in RRMS treated with Tysabri

Vitamin D supplementation reduces relapse rate in relapsing-remitting multiple sclerosis patients treated with natalizumab.
Mult Scler Relat Disord. 2016 Nov;10:169-173.

    BACKGROUND: Vitamin D insufficiency is common among multiple sclerosis patients, and hypovitaminosis D has been associated with multiple sclerosis (MS) risk and disease activity.

    OBJECTIVE: To investigate how recommendations on vitamin D3 supplements affect 25-hydroxyvitamin D (25(OH)D) levels in patients with relapsing-remitting MS (RRMS) and to examine the clinical effects associated with changes in 25(OH)D ...
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Low vitamin D predicts early conversion to SPMS

A low vitamin D status at diagnosis is associated with an early conversion to secondary progressive multiple sclerosis.
J Steroid Biochem Mol Biol. 2016 Nov;164:254-257.

    Low circulating 25-hydroxyvitamin D (25(OH)D) levels have been associated with an increased risk of relapses in relapsing remitting multiple sclerosis (RRMS), but an association with disability progression is uncertain. Lower 25(OH)D levels are found in secondary progressive MS (SPMS) when compared to RRMS. We hypothesized that a poor vitamin D ...
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Magnesium Supplementation in Vitamin D Deficiency

Magnesium Supplementation in Vitamin D Deficiency.
Am J Ther. 2017 May 3.

    BACKGROUND: Vitamin D and magnesium (Mg) are some of the most studied topics in medicine with enormous implications for human health and disease. Majority of the adults are deficient in both vitamin D and magnesium but continue to go unrecognized by many health care professionals.

    AREAS OF UNCERTAINTY: Mg and vitamin D are used by all the organs in the body, and their ...
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RE PLANT BASED FATTY ACIDS MAY LOWER RISK OF M.S

HI Friends please read
https://overcomingms.org/plant-based-fa ... isk-of-ms/

A recent study reported at ECTRIMS (European Committee for Treatment and Research in MS) in Barcelona reports that higher intake of plant-based essential fatty acids, such as alpha linolenic acid in flaxseed oil, may reduce the risk of developing Multiple Sclerosis.

Examining data from the Nurses Health Study on nearly 180,000 nurses in the US, investigators found that individuals who consumed the ...
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2017 trial: Magnesium and wound healing, metabolic status

who knew; even a relatively low input of a relatively low quality supplemental form of magnesium can provide benefits:

Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial
https://link.springer.com/article/10.10 ... 017-1056-5

Hypomagnesemia is associated with the development of neuropathy and abnormal platelet activity, both of which are risk factors for diabetic foot ulcer (DFU). This study ...
Read more : 2017 trial: Magnesium and wound healing, metabolic status | Views : 474 | Replies : 0


 

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