Epigallocathecin gallate (EGCG) inhibits the dihydrofolate reductase (DHFR) enzyme.
- The antifolate activity of tea catechins.
Binding of natural and synthetic polyphenols to human dihydrofolate reductase.
EGCG also inhibits the absorption of dietary folate.
- Effect of epigallocatechin gallate on drug transport mediated by the proton-coupled folate transporter.
DHFR lies ...