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Lipoic acid + acetyl-L-carnitine

Here's an interesting paper on lipoic acid. Although it's not MS (Parkinson's Disease), R-lipoic acid combined with acetyl-L-carnitine was found to be 100 to 1000 more effective than either alone in protecting mitochondria in a cellular Parkinson's Disease model.


Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.
J Cell Mol Med. 2008 Jun 20.

Mitochondrial dysfunction and oxidative damage are highly involved in the pathogenesis of Parkinson's ...
Read more : Lipoic acid + acetyl-L-carnitine | Views : 3506 | Replies : 10


Lipoic acid inhibits Ifn-gamma in NK cells

Here's a recent paper on lipoic acid from the Oregon Health & Science University discussing a pathway which may be partly responsible for lipoic acid's beneficial effects in MS.


Lipoic acid stimulates cAMP production via the EP2 and EP4 prostanoid receptors and inhibits IFN gamma synthesis and cellular cytotoxicity in NK cells. J Neuroimmunol. 2008 Aug 13;199(1-2):46-55.

The antioxidant lipoic acid (LA) treats and prevents the animal model of multiple sclerosis (MS), experimental autoimmune encephalomyelitis ...
Read more : Lipoic acid inhibits Ifn-gamma in NK cells | Views : 1348 | Replies : 1


CoQ10?

Can anyone tell me if CoQ10 is actually beneficial to the treatment of MS and how? Thank you!

My daughter has been taking 200 mg a day for approx. 5-6 weeks. She has just started Rebif (2 weeks ago). SOmeone asked me why she was supplementing with CoQ10 and that it could effect her liver (?)

She is also taking 1000mcg of B12, 400 iu of Vitamin D and 1000 mg of Omega 3 fish ...
Read more : CoQ10? | Views : 1865 | Replies : 1


fingolimod

Hallo to all....

Today I have been looking for something on net, and I found an article about fingolimod, so here is link...


http://www.webmd.com/multiple-sclerosis ... fingolimod


Have a nice day :wink:
Anita
Read more : fingolimod | Views : 1214 | Replies : 0


Micronutrient status and disease

i haven't read or sourced this thoroughly yet, but it's interesting so far:

http://www.pnas.org/content/103/47/17589.full
"...I propose DNA damage and late onset disease are consequences of a triage allocation response to micronutrient scarcity..."

http://www.pnas.org/content/103/47/1758 ... nsion.html
Table 1. Selected micronutrient inadequacy in the U.S.
Read more : Micronutrient status and disease | Views : 1332 | Replies : 0


Haptens can trigger MS

I am author of a poster about environmental and genetic factors which can trigger MS. This poster is on my: http://www.haptens.republika.pl/images/poster.jpg
This poster had number P15 and was presented at International Conference "Advances in Clinical Neuroimmunology", which took place on 7-8 December 2007 in Poznan, Poland. I have evidence that MS is relatively easy to predict, prevent and arrest.
Jerzy Grzeszczuk
Read more : Haptens can trigger MS | Views : 7184 | Replies : 22


Useful website: Quackwatch

I just wanted to make sure psople were aware of this extremely useful site

http://www.quackwatch.org/index.html

I would highly recommend using it as a "filter" to protect yourself from being scammed.

Take care.
Read more : Useful website: Quackwatch | Views : 1703 | Replies : 3


Esperanza Peptide anybody

Hi, I am just wondering of anybody is using or has considered using Esperanza Petide. They claim all sorts of benefits ofcourse but is it worth its money ? :wink:
Read more : Esperanza Peptide anybody | Views : 2433 | Replies : 5


Creatine

Looking into supplementation of creatine for mitochondrial energy enhancement and fatigue relief. Anyone using creatine monohydrate supplements?


http://www.scq.ubc.ca/creatine-from-muscle-to-brain/


While the role of creatine in preventing muscle (peripheral) fatigue for high performance athletes is well understood, its biochemical role in prevention of mental (central) fatigue is not. Creatine is abundant in muscles and the brain and after phosphorylation used as an energy source for adenosine triphosphate synthesis. Using double-blind placebo-controlled ...
Read more : Creatine | Views : 6137 | Replies : 19


Pilot Study: Naturopathic Medicine for MS

Hi all

Here's a link to an article (pdf) that may be of interest to some.
A Randomized Pilot Study of Naturopathic Medicine in Multiple Sclerosis

Conclusions: Naturopathic medicine combined with usual care for MS showed a trend in improvement in the General Health subscale of the SF-36, Timed Walk, and neurologic impairment. Evaluation of naturopathic medicine, as a multimodality regimen, warrants further investigation.

Now if we could just convince them to add normal ...
Read more : Pilot Study: Naturopathic Medicine for MS | Views : 1633 | Replies : 1


 

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