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A board to discuss the anticipated multiple sclerosis treatment Rituxan.

Rituximab may be an effective treatment for SPMS

Targeting B cells implicated in progressive multiple sclerosis with rituximab (Rituxan) therapy might help patients diagnosed with the disease, according to data from a small study reported here.......... ... ageid/1394
Read more : Rituximab may be an effective treatment for SPMS | Views : 2697 | Replies : 7


This section is very quiet..

Does no one take this medication?

I had an infusion in November and, according to the studies that I am familiar with, I have an 80% chance of avoiding a relapse next year.

That and vitamin D may help enourmously for the foreseeable future.

But no one seems to interested, why is this?

I suppose no one will read this post anyway..
Read more : Hellooooo | Views : 2024 | Replies : 1

first infusion yesterday

Had my first infusion of Rituxan yesterday at UCSF. Had a slight infusion reaction about two hours in that resulted in nothing more than a very itchy throat. They cut the flow, added more Benadryl, and we started again about 20 minutes later. Because of this hiccup whole infusion lasted about 7 hours.

After several denials my insurance (Blue Shield of California) agreed to pay for it thanks to a letter from my neurologist, Dr. ...
Read more : first infusion yesterday | Views : 2354 | Replies : 1

first infusion

I had my first infusion yesterday at the Royal London hospital. I experienced no side effects whatsoever. It took nearly five hours to complete the infusion (600ml commencing with 30ml/hour, increasing by an extra 30 ml/hour every thirty minutes, the titration was slowed for a while due to lowish blood pressure)...
Read more : first infusion | Views : 3565 | Replies : 6

My son is in a study using Rituximab for Type1 Diabetes...

I'm new on these forums, having just received a probable dx of MS (still need MRI) this week. I don't know much about Rituximab as a treatment for MS, but my 15yo son has been in a TrialNet study for the past two years in which they have studied it with new Type 1 diabetes patients. The results have been very, very promising!
Read more : My son is in a study using Rituximab for Type1 Diabetes... | Views : 2258 | Replies : 0

Intravenous Steroids CAUSING bladder problems?

Seems as though every time I get infused with methylprednisone (recently had 3 day course), or when I was getting cytoxan + methylprednisone, a day or two after the infusions I experience absolutely horrible bladder problems, to the point of straight up incontinence (or having to use bathroom every 5-10 minutes). Has anyone else experienced this? Any suggestions? Haven't had any luck researching it online. Thanks.
Read more : Intravenous Steroids CAUSING bladder problems? | Views : 2444 | Replies : 0


I was going through the clinical trials list and saw that Ocrelizumab is, or is still recruiting for phase 2. I'm wondering if this is really just Rituxan with a more complicated name or is this a way to get around the financial loss of a soon to expire patent on Rituxan? They must have tweaked it more than just the name.
Read more : Ocrelizumab | Views : 4505 | Replies : 10

Rituxan patients

Are there any others out there with RRMS that have taken Rituxan? or is it just me? curious as to what others experiences have been.

Thanks in advance :)
Read more : Rituxan patients | Views : 2873 | Replies : 0

new info? or not

I didn't see this posted so.... here it is. Question, how does Rituximab differ from the other monoclonal antibodies such as Campath and Tysabri?
Thanks Lars

Breaking News from Dr. Vollmer

In the development of new therapies for multiple sclerosis, there are occasions in which the results of a study surprise investigators and challenge their long-held beliefs about MS. A recent example is the evolving story concerning the development of a drug called rituximab ...
Read more : new info? or not | Views : 2786 | Replies : 3

Rituxan Found Effective in Subset of PPMS Patients

Here's an abstract from a study that will be presented at the upcoming American Academy of Neurology meetings in April.

In simple terms, it found that Rituxan appeared to impede the progression of PPMS in male patients under the age of 51 who had enhancing lesions.

Unfortunately, I am a male patient with PPMS under the age of 51 who does not have enhancing lesions, and Rituxan has done nothing for me.

At any rate, ...
Read more : Rituxan Found Effective in Subset of PPMS Patients | Views : 2884 | Replies : 3


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