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Discuss Tecfidera (BG-12, dimethyl fumarate) as an oral treatment for multiple sclerosis.

PML death linked to Tecfidera

The brain infection progressive multifocal leukoencephalopathy (PML) has killed a Dutch psoriasis patient who was taking a high dose of a drug with ingredients similar to Tecfidera.

Tecfidera is used for multiple sclerosis, which the Dutch patient didn’t have, and the medicine was made in a compounding pharmacy and not by Biogen. Yet, according to, doctors claim the case suggests the infection could emerge in people who aren’t showing warning signs...... Read More - ...
Read more : PML death linked to Tecfidera | Views : 1844 | Replies : 0

very late period.

I have been on tec since the 5th jan and i had a normal peroid in feb but it has now been 56 days since last period and i am definately not pregnant.
Is this happening to anyone else? how long did you have to wait between periods?
And did it make your period worse when it came on again?
Thanks for any reply, im freaking out a bit ...
Read more : very late period. | Views : 1506 | Replies : 0

BG12 ...compounding pharm

Cigna denied my script for tec so I found a compounding pharmacy in Houston..the cost is 150.00 per
Mo. Walgreens cost for tec is 11,000 per mo. Big pharm is very proud of this stuff! Keep plugging along, don't give up!
Read more : BG12 ...compounding pharm | Views : 1358 | Replies : 1

**IMPORTANT** PML & Tecfidera

I can't help it...I need to know that others are seeing this, too, especially if you are JC-Virus positive, and are currently taking Tecfidera. This is an excellent article!

Please let me know your thoughts. I'm just a little bit freaked out...
Read more : **IMPORTANT** PML & Tecfidera | Views : 2581 | Replies : 6

Joint Pain

Hi everyone, new to the board but not MS. I had been taking Copaxone since I was diagnosed in 2006. But I've recently began taking Tecfidera twice a day. I've had some flushing in the beginning and I learned to take the meds w food. Otherwise I will have terrible stomach pain. But my main issue seems to be this joint pain. I've never had it before but maybe a month into taking this I ...
Read more : Joint Pain | Views : 2159 | Replies : 3

Starting Tecfidera Soon

Hey everyone I'm a new MS diagnosed 23 year old choosing to have tecfidera ordered as my first medication. Do any of you have any advice for me? Is this a good option for my first medication? I appreciate the support.
Read more : Starting Tecfidera Soon | Views : 1749 | Replies : 2

Low CD8+ T cell counts found with MS drug Tecfidera

A recent study found that patients taking dimethyl fumarate (Tecfidera) had low counts of CD8+ T cells, though their overall levels of lymphocytes were within the normal range. The findings suggest that doctors may want to monitor specific lymphocyte levels in addition to doing full blood cell counts.

In November 2014, Biogen Idec confirmed its first case of progressive multifocal leukoencephalopathy (PML), a rare brain infection, in a patient taking dimethyl fumarate (Tecfidera), and complications ...
Read more : Low CD8+ T cell counts found with MS drug Tecfidera | Views : 1766 | Replies : 0

Problems I wonder if anyone has encountered.

I recently was diagnosed with MS in March of 2014. Of course with my luck, the week I went blind in my left eye every neuro-opthalmologist happened to be on a convention, so for a whole week i was tossed around to 5 different eye doctors, then finally me being in the medical field & worried I had a tumor behind my eye, asked the last doctor for a referral for an MRI on my ...
Read more : Problems I wonder if anyone has encountered. | Views : 2353 | Replies : 2

FDA adds rare brain infection link to Tecfidera label

FDA adds rare brain infection link to MS drug Tecfidera labelling

The death from a serious brain infection of a patient taking Biogen Idec's big-selling oral multiple sclerosis therapy Tecfidera has prompted an update to the drug's label in the US.

The FDA issued a notice describing the case of a patient on Tecfidera (dimethyl fumarate) who developed progressive multifocal leukoencephalopathy (PML), the same condition that caused Biogen Idec's injectable MS therapy Tysabri (natalizumab) to ...
Read more : FDA adds rare brain infection link to Tecfidera label | Views : 1704 | Replies : 1

Tecfidera vs no med

Hello everybody. Thanks for reading my post.
I was diagnosed with MS 7 years ago after an optic neuritis which was treated with esteroids which help me to a full recovery. I had
another flare up in March this year which affected the sensitivity of both my legs but I fully recoverd after a month. I have NEVER used any medication. I feel good, have no signs of tiredness whatsover, I swim on a daily ...
Read more : Tecfidera vs no med | Views : 4804 | Replies : 8


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