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A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis

MS Patient dies from anti-Tysabri antibodies

Svenningsson and colleagues concluded that her death resulted from "rebound neuroinflammation as a result of the development of natalizumab anti-drug antibodies."

Noteworthy was that the patient had shown unusual reactions to the drug starting with the fourth infusion, including chills and fever, they suggested.

"We recommend that repeated moderate to severe infusion reactions in the beginning of natalizumab treatment should prompt the cessation of treatment and assessment for the development of natalizumab anti-drug antibodies," Svenningsson ...
Read more : MS Patient dies from anti-Tysabri antibodies | Views : 1023 | Replies : 0


MS-UK Tysabri User Diaries

MS-UK Tysabri Diary Update

Kirsty has kindly sent in her 25th Tysabri Infusion Diary update.

You can read it at http://www.ms-uk.org/index.cfm/kirsty
Read more : MS-UK Tysabri User Diaries | Views : 1722 | Replies : 9


Biogen to Pay Elan $3.25 Billion for Full Tysabri Rights

Biogen Idec Inc. agreed to acquire partner Elan Corp.’s stake in the multiple sclerosis drug Tysabri for $3.25 billion in cash plus future royalties.

The deal gives Biogen all rights to the product, and the company will pay royalties to Elan, Dublin-based Elan said in a statement today. The companies had been splitting profit equally on the medicine, which generated $1.6 billion in sales in 2012.

The deal ends speculation that Biogen would buy Elan ...
Read more : Biogen to Pay Elan $3.25 Billion for Full Tysabri Rights | Views : 916 | Replies : 3


PML info in regards to MS treatment

http://www.ccjm.org/content/78/Suppl_2/S33.full

A bit of info regarding PML and how it relates to MS patients on Tysabri. It may all be well know, but5 it answered a few of my own questions so I thought I would share.
Read more : PML info in regards to MS treatment | Views : 1354 | Replies : 7


First-line use of Tysabri in anti-JCV antibody negative pts

Applications for first-line use of Tysabri in anti-JCV antibody negative patients with MS announced

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Biogen Idec and Elan Corporation, plc have announced that they have submitted applications to the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) requesting updates to the Tysabri® (natalizumab) labels. The applications request an expanded indication that would include first-line use for people living with certain relapsing forms of multiple sclerosis (MS) who have tested negative for ...
Read more : First-line use of Tysabri in anti-JCV antibody negative pts | Views : 1117 | Replies : 2


Tysabri is doing AMAZINGLY for me until the last week

Like the last week to week and a half it's like I'm not on any medication and I relapse really hard. As far as I know there is only one type of dose, what are some solutions your doctor has for you? My next infusion is coming up and I'll ask my doctor then.
Read more : Tysabri is doing AMAZINGLY for me until the last week | Views : 1113 | Replies : 1


JC Virus Test Vs. Tysabri Antibody T itre

Hello,

Does anyone know the difference between the JCVirus and the Tysabri Antibody Titre?
Read more : JC Virus Test Vs. Tysabri Antibody T itre | Views : 1571 | Replies : 9


Tsyabri Efficacy Rate

Does anyone know the efficacy rate of Tysabri? I tried to find it on pubmed, but I don't really know where to look in the endless reports.
Read more : Tsyabri Efficacy Rate | Views : 1303 | Replies : 7


PML Cases now reach 312

Unfortunately the number of PML cases has made another significant jump by 10 in the last month, bringing the total to 312. Don't know if any more deaths have resulted.

http://chefarztfrau.de/?page_id=716

Harry
Read more : PML Cases now reach 312 | Views : 1442 | Replies : 4


Endless illness

Just curious if anyone has gone through the things I have. Started Tysabri 2 months ago so, 2 infusions. I have not stopped vomiting and having diarreah since then. Terrible stomach pain and constant nausea. My Neuros seem a bit lost and only hear that I possibly developed an antibody to Tysabri. I have researched a ton and have not found any similar long term issues. They suspended my infusions immediately and I have been ...
Read more : Endless illness | Views : 1430 | Replies : 5


 

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