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A board to discuss the newly-released drug Tysabri, (formerly known as Antegren) as a treatment for Multiple Sclerosis

PML Cases now reach 410!

The number of known PML cases has now reached 410, an increase of 9 over the previous month. Don't know how many more deaths are involved in this number.

Read more : PML Cases now reach 410! | Views : 1670 | Replies : 0

IgM antibody identifies good candidates for natalizumab

Researchers in Spain have identified lipid-specific antibody bands in the cerebrospinal fluid (CSF) that are associated with an aggressive presentation of multiple sclerosis (MS), and patients with these antibodies seem to have a much lower risk for progressive multifocal leukoencephalopathy (PML) with natalizumab therapy (Tysabri, Biogen Idec).

"The presence of lipid-specific IgM bands in the CSF signals patients with aggressive disease and highly activated immune systems," said Luisa Villar, PhD, Hospital Ramón y Cajal, Madrid, ...
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Tysabri may be possible for more MS patients with new test

A blood test for L-selectin expression on circulating immune cells may identify multiple sclerosis patients who could safely receive natalizumab (Tysabri) despite past exposure to the JC virus, a small study presented here suggested.

All MS patients taking natalizumab who developed the rare but life-threatening brain inflammation called progressive multifocal leukoencephalopathy (PML) in the study had very low levels of L-selectin expression, which was not seen in other patients who did not develop PML or ...
Read more : Tysabri may be possible for more MS patients with new test | Views : 1811 | Replies : 1

New Tysabri data from ECTRIMS

New Tysabri data show earlier treatment & longer-term use result in significant reductions in MS disease activity

Biogen Idec announced results from several new analyses of Tysabri(R) (natalizumab) data that demonstrate its effectiveness in reducing multiple sclerosis (MS) disease activity. This effect was particularly significant in people with relapsing MS who initiated treatment when they had lower Expanded Disability Status Scale (EDSS) scores as well as in those who have been treated for more than ...
Read more : New Tysabri data from ECTRIMS | Views : 1587 | Replies : 1

Short survey for my school leaving examination work :)

Dear MS-Patient,

Twelve years ago my mother came down with MS. The nescience about this theme has really employed me. That’s why I decided to make my work for general qualification for university entrance about this interesting issue.
I’m conscious of not-being the first guy who wants to do this and I’m also not the last one. However I would be really thankful if you would take just five or ten minutes to answer to ...
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Biogen Idec, Elan facing suits over MS drug side effects

Despite living with multiple sclerosis since 1997, Kimberley A. Yout kept a busy schedule, working full time as a money manager for a Boston bank and modeling in her spare time.

That changed on Aug. 28 of last year when Yout, 45, was diagnosed with a rare brain infection that developed as a side effect of Tysabri, a drug she took for six years to keep her MS in check. Yout’s speech became slurred, her ...
Read more : Biogen Idec, Elan facing suits over MS drug side effects | Views : 2093 | Replies : 7

Tysabri rebound?

There is some research data about "tysabri rebound" effect.. but what causes it? Is there any scientific data about it?
Read more : Tysabri rebound? | Views : 1852 | Replies : 3

touch program

anybody else think that the biggest problem with Tysabri, besides the fear of PML, is the annoying phone calls from the drug reps. If you don't return the call, they start blowing up your phone and emailing you. If you do return the call, they have nothing to say except repeat stock phrases from the brochures, the feign concern, and then have a scary serious tone that makes you wonder what the previous calls to ...
Read more : touch program | Views : 1286 | Replies : 1

PML Cases now 372

The number of PML cases has risen another 13 during the past month, bringing the new total to 372. It isn't slowing down!

Read more : PML Cases now 372 | Views : 1884 | Replies : 4

Sister just diagnosed with PML

My sister was just diagnosed with PML on Monday and I am just looking for another individuals who have gone through this! If anyone can point me in the right direction or has had PML and wouldn't mind sharing their experience it would be MUCH appreciated! Thank you!
Read more : Sister just diagnosed with PML | Views : 2517 | Replies : 5


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