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September 10, 2012 (San Francisco, California) — At least 17 patients taking natalizumab have experienced serious herpes simplex or varicella zoster infections since November 2004, researchers reported here at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy.
Most of the patients underwent long hospitalizations and received systemic antiviral therapy; 2 died.
The risk for central nervous system (CNS) infection is already included in the labeling of natalizumab, but this research confirms the danger, first ...
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