I am a 45 yrs old woman and on rebif for 3 months and feel fatigued w/ weak left leg that becomes a weight after a short walk. I seriously started questioning whether this is helping me or making me worse, thus found this website. (thank god!) my M.D. seems to think Rebif is a proven helper and if my injection sites don't get too bad (lots of redness for a month!) that I should continue on. But, I also feel an inner sadness and dunno why - am I just getting more depressed because of MS or is Rebif causing depression? I am still pooped the day after the shot and feel like all I wanna do is stay in bed, get online or eat.
I use a numbing cream (betacaine) for one hour before rebijection. I can't bring myself to do it manually. I really wonder if I should go off it.
thx for sharing all of you.