Injection location and side effects

A board to discuss the Multiple Sclerosis modifying drug Rebif

Injection location and side effects

Postby Punchy » Mon Jan 28, 2008 11:08 am

Anyone find a correlation between the injection location and intensity of side effects?

I am definitely starting to see a pattern. When I inject in my stomach, the next day isn't so bad. But when I inject in my leg, it's horrible - every time.

I'm now at the point where I only inject my leg once a week, on Friday night, because otherwise I wouldn't make it to work the next morning. My poor stomach is getting pretty lumpy now.
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Postby scoobyjude » Wed Jan 30, 2008 8:23 pm

Punchy, I too felt more achey and tired the next day after leg shots. I assumed that maybe I have more muscle than fat and that had something to do with it. I really haven't noticed a pattern with my stomach, arms or hips though. Sometimes I feel great, sometimes not so much.
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Postby oreo » Thu Jan 31, 2008 7:30 am


I don't use my legs or butt because I develop nasty lumps that last for days afterwards and are most uncomfortable - especially anywhere that involves sitting on them. Therefore I stick to my stomach - fortunately there is plenty to work with.

I do remenber having more after-effects before I started pre-warming my injections and taking Tylenol 1/2 hour ahead of the shots. If you don't do either of these, I suggest you give them a try.
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