I wanted to wrap up some loose ends on this thread. I’ll be taking a break from posting, and I felt it was important that people have some resources for continuing the discussion of the links between endothelial dysfunction and multiple sclerosis-
These men and their teams are leading the research into the endothelium and the breech of the blood brain barrier in MS. This breech in the blood brain barrier allows cells to enter the CNS that should not be there. These doctors/researchers believe the signaling molecule of nitric oxide controls the process.
Berislav V. Zlokovic, MD, PhD
The University of Rochester Center for Neurodegenerative and Vascular Brain Disorders
link to Dr. Zlokovic's page
Professor Kenneth Smith, King’s College London
Wolfson Center for Age related diseases and multiple sclerosis
link to Dr. Smith's page
I would change nothing in my original paper. I believe the protocol works, and will slow down MS progression. If someone tries the protocol for three months and does not see remission, please post your findings. (money back guarantee!) If there are fine-tunings to the vitamin and mineral supplementation, please post as well. I’ll keep the paper up for another year (I have to pay for hosting.)
This theory encompasses all of the current scientific research in MS. Nitric oxide controls the blood vessels dilation, contraction, permeablility of the BBB and the body’s immune response. Nitric oxide signaling is disrupted by low vitamin D, hormonal imbalance, toxins, viruses, bacteria, heavy metals, trans fats, excess glucose, high altitude, cigarette smoking, alcohol as well as lifestyle factors like excess stress and lack of sleep.
Nitric oxide signaling can be repaired by high antioxidant intake, vitamin D supplementation and hormonal balance, proteolytic enzymes, regular exercise, a lowfat diet, and reduction in stress.
Until we have further scientific evidence of the linkage between endothelial dysfunction and multiple sclerosis, there’s no use just throwing out suppositions and arguing. It’s like religion....without scientific evidence, it must be on faith. I believe science will continue to prove this theorum...but only time will tell. I need my time back to take care of myself, my family and my previous professional and personal life. I appreciate all the fine minds here on thisisms. Jeff and I never would have found his stability and health without eveyone’s help.
Goodbye, and thanks for all the fish (Dr. Swank!)
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
dual stents placed 5/09
CCSVI in MS