There is no evidence to suggest that continuous steroid administration slows progression of MS or improves symptoms over a long period of time. The side effects of long-term continuous steroid use are serious and well-documented. These include stomach ulcers, weight gain, acne, cataracts, osteoporosis (thinning of the bones), deterioration of the head of the thigh bone, and chemical diabetes.
Oral steroids that have been taken over a long period of time should never be stopped abruptly, since they can suppress the body's own steroid production by the adrenal gland. Gradually tapering the dose downward before discontinuation of the medication allows the body time to normalize production.