Discussion of statins (Lipitor, Zocor, etc.) in the treatment of MS.


Postby jimmylegs » Wed May 31, 2006 5:54 am

hi i searched this forum for niacin/b3 and got no results. is anyone taking niacin as an alternative to, or in combination with, prescription statins?
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Postby ljm » Fri Jun 02, 2006 6:00 pm

I've tried unsuccessfully to find out whether niacin is as effective as a statin in decreasing inflammation. As it turns out, I'm taking niacin, rather than statins, because I think its "vasodilation" effect might help that neurological micro environment, and its easier to get as well, and maybe also helps depression. I take 100 mg x 3 times per day. Unfortunately I'm feeling rather crappy so I'm not a real testimony for its effectiveness. And, I think niacin shares the risk of statin in long term use/liver damage.
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Postby LisaBee » Thu Jun 08, 2006 3:37 pm

I was taking a prescription niacin/statin combo last fall, called Advicor. I felt pretty good overall. I got sick one night and threw up. It may or may not have been the medication, as there was a bug circulating the workplace and I was only sick one night, but it made me nervous because I wasn't getting the liver function monitoring (a long story about health insurance). So I stopped taking it.

I have been working on my diet, and want to work on my exercise and get blood lipids repeated this fall. If they are still not quite up to par, I want to started again on the medication for both MS and lipid purposes, and get liver function tests.

There are both sustained and immediate release niacin formalations - the kind in the prescription was sustained release.

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Nicotinamide and MS

Postby elizard » Thu Nov 09, 2006 1:51 am

Actually it's Nicotinamide (B3) that worked in this mouse study:

And of course...further study is needed.
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Postby jimmylegs » Thu Sep 11, 2008 6:48 pm

wow, this is so old. missed the feedback at the time, obviously. i was doing a little random searching in google which led me to this old thread.
related interesting info:

hear that about possible long term liver impacts. i think that's why they offer the -amide version? also, there's always milk thistle for those pesky livers who won't behave nicely under assault ;)
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