blech to stubborn docs and nexium :S my doc gave me a sample of that stuff when I was trying to sort out my LES issues. I think I took one before I had time to read, but as soon as I started reading I decided it was a monumentally stupid drug to give people who have nutrient depletion issues in the first place. particularly mag depletion issues. and yes fwiw I do have an ms dx, 2006.
if you are eating gluten and experience GI distress incl diarrhea I would consider some alternate approaches to evaluating zinc status, given that the docs are not cooperative.
The Zinc Taste Test
"The test is based on the knowledge that the functions of taste and smell are dependent upon there being sufficient zinc available in the body. Thus, if zinc is deficient then taste function will be diminished. This principle is utilised in the taste test by offering a standard test solution of zinc sulphate for tasting. The response is then compared with a series of defined standards and the zinc status thus determined."
easy steps from the zinc taste test:
-pick up some zinc sulfate eg http://www.chemistdirect.co.uk/healthai ... _4750.html
-smash up 5 x 200mg pills into powder, and dissolve thoroughly in 1 litre of purified water.
"...Once prepared the solution should be stored in a refrigerator and discarded after six months. The solution should be removed from storage and left at room temperature for about two hours before carrying out the test."
HEY CHECK THIS OUT you can purchase prepared testing solution http://www.iherb.com/Ethical-Nutrients- ... 20-ml/3624
back to the taste test protocol...
"You take a 5-10ml sip and hold it in the mouth for ten seconds"
"There are 4 grades of response:
1. No taste: major zinc deficiency, which needs a supplement of 150mg a day.
2. No immediate taste is noticed but, within the ten seconds, a ‘dry’ or ‘metallic’ taste is experienced: Moderate deficiency, needing a supplement of 100 mg of zinc per day.
3. An immediate slight taste which increases over the ten second period: Minor deficiency: requiring a supplement of 50 mg per day.
4. An immediate, strong and unpleasant taste: No zinc deficiency exists, no need for a supplement."
note that you might not like how it feels taking more than 50mg of zinc at one time. so if you find yourself in a situation where you need 100 or 150, spread it out through the day. take with food to avoid nausea.
for the full zinc taste test protocol read more here (p. 39):
Zinc, MS and the Zinc Taste Test
By Dr Bob Lawrence, the GP with MSwww.ms-uk.org/files/npwm_2004_0023.pdf
I have not read through the test protocol in detail but logically you would supplement appropriate to a given response level for a few days, then retest. once you find 'no deficiency exists' then you could get into monthly followup taste testing to see if diet and lifestyle are keeping zinc levels steady.
FYI limiting gluten intakes would allow your body to retain zinc more easily.