Tropospheric ozone
Re: Tropospheric ozone
O3
2017 Apr 6
Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida,
Association between air pollution and mammographic breast density in the Breast Cancer Surveilance Consortium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382391/
Conclusion
Exposure to PM2.5 and O3 may in part explain geographical variation in mammographic density. Further studies are warranted to determine the causal nature of these associations.
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MS
2024 Apr 24
Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China
An exploration of causal relationships between nine neurological diseases and the risk of breast cancer: a Mendelian randomization study
https://pubmed.ncbi.nlm.nih.gov/38663930/
Conclusions: This study found the trends towards a decreased risk of ER+ breast cancer in patients with Alzheimer's disease and an increased risk in patients with multiple sclerosis.
2017 Apr 6
Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida,
Association between air pollution and mammographic breast density in the Breast Cancer Surveilance Consortium
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382391/
Conclusion
Exposure to PM2.5 and O3 may in part explain geographical variation in mammographic density. Further studies are warranted to determine the causal nature of these associations.
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MS
2024 Apr 24
Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China
An exploration of causal relationships between nine neurological diseases and the risk of breast cancer: a Mendelian randomization study
https://pubmed.ncbi.nlm.nih.gov/38663930/
Conclusions: This study found the trends towards a decreased risk of ER+ breast cancer in patients with Alzheimer's disease and an increased risk in patients with multiple sclerosis.
https://www.eboro.cz
Re: Tropospheric ozone
2024 Feb 14
Department of Environmental Health, Boston University School of Public Health, Boston
Warm season ambient ozone and children's health in the USA
https://pubmed.ncbi.nlm.nih.gov/38553030/
Conclusions: Results from this national study extend prior research on the impacts of daily O3 on children's health and reinforce the presence of important adverse health impacts even at levels below the current regulatory standard in the USA.
Department of Environmental Health, Boston University School of Public Health, Boston
Warm season ambient ozone and children's health in the USA
https://pubmed.ncbi.nlm.nih.gov/38553030/
Conclusions: Results from this national study extend prior research on the impacts of daily O3 on children's health and reinforce the presence of important adverse health impacts even at levels below the current regulatory standard in the USA.
https://www.eboro.cz
Re: Tropospheric ozone
O3
September 2018
Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by IL-33
https://www.sciencedirect.com/science/a ... 4918300289
..Conclusion
Data demonstrate that ozone causes an immediate barrier injury that precedes myeloid cell–mediated inflammatory injury under the control of the IL-33/ST2 axis. Thus IL-33/ST2 signaling is critical for maintenance of intact epithelial barrier and inflammation.
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Neurodegenerative disorders
2024 May
ST2 levels and neurodegenerative diseases: is this a significant relation?
https://pubmed.ncbi.nlm.nih.gov/38694387/
..Some studies have found a link between changes in the IL-33/ST2 pathway and neurodegenerative disorders. This review article investigates the relationship between the interleukin-33 (IL-33)/ST2 pathway and neurodegenerative disorders
September 2018
Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by IL-33
https://www.sciencedirect.com/science/a ... 4918300289
..Conclusion
Data demonstrate that ozone causes an immediate barrier injury that precedes myeloid cell–mediated inflammatory injury under the control of the IL-33/ST2 axis. Thus IL-33/ST2 signaling is critical for maintenance of intact epithelial barrier and inflammation.
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Neurodegenerative disorders
2024 May
ST2 levels and neurodegenerative diseases: is this a significant relation?
https://pubmed.ncbi.nlm.nih.gov/38694387/
..Some studies have found a link between changes in the IL-33/ST2 pathway and neurodegenerative disorders. This review article investigates the relationship between the interleukin-33 (IL-33)/ST2 pathway and neurodegenerative disorders
https://www.eboro.cz
Re: Tropospheric ozone
O3
2024 May 1
State Key Laboratory of Organic Geochemistry and Guangdong Provincial Key Laboratory of Environmental Protection and Resources Utilization, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, China
Ozone Chemistry on Greasy Glass Surfaces Affects the Levels of Volatile Organic Compounds in Indoor Environments
https://pubmed.ncbi.nlm.nih.gov/38691770/
Abstract
The chemistry of ozone (O3) on indoor surfaces leads to secondary pollution, aggravating the air quality in indoor environments. Here, we assess the heterogeneous chemistry of gaseous O3 with glass plates after being 1 month in two different kitchens where Chinese and Western styles of cooking were applied, respectively. The uptake coefficients of O3 on the authentic glass plates were measured in the dark and under UV light irradiation typical for indoor environments (320 nm < λ < 400 nm) at different relative humidities. The gas-phase product compounds formed upon reactions of O3 with the glass plates were evaluated in real time by a proton-transfer-reaction quadrupole-interface time-of-flight mass spectrometer. We observed typical aldehydes formed by the O3 reactions with the unsaturated fatty acid constituents of cooking oils. The formation of decanal, 6-methyl-5-hepten-2-one (6-MHO), and 4-oxopentanal (4-OPA) was also observed. The employed dynamic mass balance model shows that the estimated mixing ratios of hexanal, octanal, nonanal, decanal, undecanal, 6-MHO, and 4-OPA due to O3 chemistry with authentic grime-coated kitchen glass surfaces are higher in the kitchen where Chinese food was cooked compared to that where Western food was cooked. These results show that O3 chemistry on greasy glass surfaces leads to enhanced VOC levels in indoor environments.
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Neurodegeneration
19 Dec 2023
Association between Volatile Organic Compounds and Serum Neurofilament Light Chain in Us Adults
https://papers.ssrn.com/sol3/papers.cfm ... id=4668643
Abstract
Objective: This study aimed to investigate the associations between exposure to blood volatile organic compounds (VOCs) and the level of serum neurofilament light chain (NfL) in American adults.Methods: Data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES) was utilized. We measured the levels of blood VOCs and serum NfL and used multiple linear regression models to analyze the correlation after adjusting for covariates. Stratified analyses were also conducted based on gender.Results: The study found that blood ethyl acetate and o-xylene were positively associated with elevated serum NfL levels. Gender stratified analysis revealed significant associations between male serum NfL levels and 2,5-dimethylfuran, ethyl acetate and 1,1,1-trichloroethane, while no similar significant associations were found in women.Conclusion: Exposure to blood VOCs is related to elevated serum NfL levels in US adults with potential gender-specific effects. These findings suggest that blood VOCs may play a role in revealing neurodegeneration and impacting neurological health.
2024 May 1
State Key Laboratory of Organic Geochemistry and Guangdong Provincial Key Laboratory of Environmental Protection and Resources Utilization, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, China
Ozone Chemistry on Greasy Glass Surfaces Affects the Levels of Volatile Organic Compounds in Indoor Environments
https://pubmed.ncbi.nlm.nih.gov/38691770/
Abstract
The chemistry of ozone (O3) on indoor surfaces leads to secondary pollution, aggravating the air quality in indoor environments. Here, we assess the heterogeneous chemistry of gaseous O3 with glass plates after being 1 month in two different kitchens where Chinese and Western styles of cooking were applied, respectively. The uptake coefficients of O3 on the authentic glass plates were measured in the dark and under UV light irradiation typical for indoor environments (320 nm < λ < 400 nm) at different relative humidities. The gas-phase product compounds formed upon reactions of O3 with the glass plates were evaluated in real time by a proton-transfer-reaction quadrupole-interface time-of-flight mass spectrometer. We observed typical aldehydes formed by the O3 reactions with the unsaturated fatty acid constituents of cooking oils. The formation of decanal, 6-methyl-5-hepten-2-one (6-MHO), and 4-oxopentanal (4-OPA) was also observed. The employed dynamic mass balance model shows that the estimated mixing ratios of hexanal, octanal, nonanal, decanal, undecanal, 6-MHO, and 4-OPA due to O3 chemistry with authentic grime-coated kitchen glass surfaces are higher in the kitchen where Chinese food was cooked compared to that where Western food was cooked. These results show that O3 chemistry on greasy glass surfaces leads to enhanced VOC levels in indoor environments.
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Neurodegeneration
19 Dec 2023
Association between Volatile Organic Compounds and Serum Neurofilament Light Chain in Us Adults
https://papers.ssrn.com/sol3/papers.cfm ... id=4668643
Abstract
Objective: This study aimed to investigate the associations between exposure to blood volatile organic compounds (VOCs) and the level of serum neurofilament light chain (NfL) in American adults.Methods: Data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES) was utilized. We measured the levels of blood VOCs and serum NfL and used multiple linear regression models to analyze the correlation after adjusting for covariates. Stratified analyses were also conducted based on gender.Results: The study found that blood ethyl acetate and o-xylene were positively associated with elevated serum NfL levels. Gender stratified analysis revealed significant associations between male serum NfL levels and 2,5-dimethylfuran, ethyl acetate and 1,1,1-trichloroethane, while no similar significant associations were found in women.Conclusion: Exposure to blood VOCs is related to elevated serum NfL levels in US adults with potential gender-specific effects. These findings suggest that blood VOCs may play a role in revealing neurodegeneration and impacting neurological health.
https://www.eboro.cz