Mino

mrhodes40 · Post by **mrhodes40** » Mon Oct 26, 2009 2:46 pm

Minocycline is a antibiotic that is showing promise in brain damage. It is known that it down regulates microglia, the brains immune cells that are able to open the BBB, to call in T cells and b cells and to phagocytose damaged tissue in the brain.

Here is a story on Minocycline
TELEGRAPH

Dr Simka offered in one of his papers that perhaps Mino could be used post procedure to moderate any immune reactions left over from the original damage/immune activation.

As a guess I will offer that probably progressed persons in particular will have a lot of iron the body will want to clean up and remove... THAT is pure speculation on my part. I can't help it sorry

SammyJo · Post by **SammyJo** » Mon Oct 26, 2009 3:10 pm

Sharon was saying they put you on antibiotics post stent procedure, is it possible to request mino?

Do you have any idea on iron clean up?
I noted your earlier comments on iron, I thought you said best to leave it alone, don't over supplement or withhold, just normal food amounts, if you aren't anemic.

mrhodes40 · Post by **mrhodes40** » Mon Oct 26, 2009 3:55 pm

Oh my. Well, here's the thing; you can't likely manipulate the iron leaking by altering your intake or iron levels that I know of. You might as well say that if you manipulate your iron levels you would reduce the amount of blood that would leak out a cut. It does not make sense to think that by changing the iron content of the blood you could make a difference there.

you might help the situation by stopping the leak....

What I am suggesting is that the body's natural reaction to the iron is to try to clean it up with immune cells and perhaps the persons with more iron in the brain will need some help there. I am not suggesting anyone ask for minocycline antibiotics........... just offering information for discussion. The mino article is cool huh?

I got antibiotics because I had a catheter as a preventative for a UTI...mino would not help that at all.

radeck · Post by **radeck** » Tue Oct 27, 2009 8:20 am

Definitely very interesting news, Marie. It's interesting to read, in the actual journal article, that the effect of the Mino is dose-dependent, i.e. it harms in high doses. The main question I have based on this is how long do lymphocytes live? I've heard somewhere sometimes (i.e. this might as well be wrong) that T cells can live decades. I suppose the fact that we keep immunizations for that long is a sign of that? If the mino were to be used to help reduce damage, would one have to use it for decades even after the CCSVI procedure?

mrhodes40 · Post by **mrhodes40** » Tue Oct 27, 2009 8:36 am

White blood cells live for a few days to a few months depending on what they are actually doing/type. Red cells live 120 days. I am unaware of any t cells living for decades; as a general rule the only cells in the body that are not replaced regularly are nerves. Your body is more like a brick house that has all the bricks replaced one at a time than it is a static thing...

bluesky63 · Post by **bluesky63** » Thu Oct 29, 2009 6:39 am

Hi there.

I don't know if this is something you'll know. I have recently started minocyclne, very low dose, for combo Lyme/MS treatment. I have also considered taking iron supplements because I am borderline anemic and I thought it might be healthy bto get my iron up before having any stenting or being on blood thinners. But now I am wondering if I should avoid the iron supplements? If you have any thoughts I would be grateful.

mrhodes40 · Post by **mrhodes40** » Thu Oct 29, 2009 8:42 am

Yes I will be very clear that if it were me, and I was anemic enough that my doctor recommended iron supplements I would take them. I also would not throw extra iron into the works unless I knew I needed it.

Sharon · Post by **Sharon** » Thu Oct 29, 2009 9:14 am

Sammy Jo -

I was placed on an drip antibiotic post procedure for the time I was in the hospital. This is a precautionary measure - I was not sent home with an antibiotic prescription. Just checked my records and my daughter's. We both had intravenous Vancocin.

Sharon