Rebound
Rebound
I'm new to the forum but I'm currently on tecfidera and have been on it for 4 months. I was on Gilenya and didn't have any relapses but decided to change after a year because of hair loss and headaches. As soon as I came off Gilenya I had major relapse transitioning to tecfidera. It took me almost two months to recover from this last relapse. I regret coming off Gilenya now but my Doc is telling me my best option is Tysarbi. I never want to go thru that type of relapse again. I never had one really bad like that before besides when I first was diagnosed 11 years ago. My question is for the people who have came off Tysarbi. Did you have a rebound effect? I did test positive for the JC at 0.45 but im more scared of the rebound more than anything. I'm fairly young at 24 and its a big time decision but this last relapse of I losesight, and walking.Please Input!
Re: Rebound
I've never been on Tysabri, but a rebound effect from people coming off of it is well known. Try searching the forums for IRIS which is Immune Reconstitution Inflammatory Syndrome.Allstar22 wrote:My question is for the people who have came off Tysarbi. Did you have a rebound effect?
Being JC virus positive puts you at increased risk of PML.
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Re: Rebound
I read recently that neurologists were only placing people on Tysabri for a maximum of 18-14 months regardless of their JCV status. So if this is true, you have a date you can set in a calendar. Check with your neurologist. Although Prednisone is not the best thing prescribed long term, in most cases it can reduce or even fend off a relapse. If I personally were in any risk for a rebound effect, i would be looking into my options to lessen the possible effects with prednisone. When I was first diagnosed (from a different diagnosis) I was on prednisone, and when I started Rebif, I had none of the side effects others talked of, and I developed after i stopped the prednisone.