grapefruit
Posted: Thu Feb 19, 2015 11:33 am
http://www.cbc.ca/news/health/grapefrui ... -1.1253489
it includes a possibly incomplete list of medications with known grapefruit interactions.
list:
Selected drugs that interact with grapefruit
it includes a possibly incomplete list of medications with known grapefruit interactions.
,Grapefruit juice is known to interact with some types of medications, leading to an overdose hazard.
andPreviously published reports showed that drinking a 200-mL glass of grapefruit juice once a day for three days produced a 330 per cent increase in the concentration of simvastatin, a commonly used statin, in the bloodstream compared with taking the medication with water.
It increases bioavailabiliy. Will it increase bioavailability of some good stuff too?"Taking one tablet with a glass of grapefruit juice is like taking 20 tablets with a glass of water," Bailey said. "This is unintentional overdosing. So it's not surprising that these levels go from what we call therapeutic to toxic."
list:
Selected drugs that interact with grapefruit
Anti-cancer
Crizotinib.
Dasatinib.
Erlotinib.
Everolimus.
Lapatinib.
Nilotinib.
Pazopanib.
Sunitinib.
Vandetanib.
Venurafenib.
Anti-infective
Erythromycin.
Halofantrine.
Maraviroc.
Primaquine.
Quinine.
Rilpivirine.
Anti-cholesterol
Atorvastatin, (lipitor)
Lovastatin.
Simvastatin.
Cardiovascular
Amiodarone.
Apixaban.
Clopidogrel.
Dronedarone.
Eplerenone.
Felodipine.
Nifedipine.
Quinidine.
Rivaroxaban.
Ticagrelor.
Central nervous system
Alfentanil (oral).
Buspirone.
Dextromethorphan.
Fentanyl (oral).
Ketamine (oral).
Lurasidone.
Oxycodone.
Pimozide.
Quetiapine.
Triazolam.
Ziprasidone.
Gastrointestinal
Domperidone.
Immunosuppressants
Cyclosporine.
Everolimus.
Sirolimus.
Tacrolimus.
Urinary tract
Darifenacin.
Fesoterodine.
Solifenacin.
Silodosin.
Tamsulosin.