In the other topic on this forum on "Bacterial toxin a potential trigger for multiple sclerosis" on general-discussion-f1/topic24167.html
we find this article on the possible role of the Epsilon toxin in MS:http://www.ms-uk.org/bacteria
It is of interest to note that the article suggests that epsilon toxin does not only target brain endothelium cells and oligodendrocytes for myelin production (and their precursor cells OPCs I guess), but also quote ...that epsilon toxin targets other cells types associated with MS inflammation such as the retinal vascular and meningeal cells.
But then, this is where it really gets interesting:
quote: Originally, we only thought that epsilon toxin would target the brain endothelium cells and oligodendrocytes; we just happened to notice that it also bound to and killed meningeal cells. This was exciting because it provides a possible explanation for meningeal inflammation and subpial cortical lesions exclusively observed in MS patients
, but not fully understood.
Then, when I looked for 'meningeal' on wikipedia which has been a great source of information for me all the time, I found something that is even more interesting: http://en.wikipedia.org/wiki/Meningeal_veins#Drainage
This wiki page brings it all together: the CSF flow, the drainage of the dural nerve system, the dural sinuses, the meningeal inflammation and, guess what.... the internal jugular veins
whow.. I believe this thinking fully confirms the concept for MS as set out on the first page of this topic.
This wiki page seems to have been common knowledge that was there all the time.
But then, I ask myself, why was this never associated with our MS condition?
Not even after so much noise was made on the social fora and in the news on the blocked internal jugular veins/ccsvi?
What is going on here?
Really, this issue is getting bigger by the day with more and more questions to be asked...