Andrey wrote:Is there any news on the calcitriol+d3 treatment?
I wonder if anyone tried this "in real life". The first news was quite a while ago and there must be at least someone who tried it...
Instead of steroids at the onset (or together?) would be very interesting.
Or maybe this just did not show any use in humans despite results with mice...
What about trials? If anyone knows some info, would be very interesting to see.
Pre-trial test wrote:The calcitriol absolutely works. And it most definitely should be used by neurologists to treat any MS attack. My personal experience was that for approximately six weeks after taking the calcitriol I had complete elimination of muscle spasticity and complete elimination of clonus. This followed the initial the fact which, to me, was akin to the "steroid high" I experienced from a course of IV Solu-Medrol. The quality of the experience, initially, was different from the anti-inflammatory effect of the steroids, as everything not only felt better, but everything actually worked better. My core control and balance improved dramatically, and my usual "bent-over" posture disappeared. Many many friends spontaneously commented on how much better I was walking. Over the past two weeks to clonus and spasticity are returning. The only side effect I experienced at 37.5 µg was a day of diarrhea.
After taking 8000 IU of vitamin D3 daily for about a year and a half, I developed a kidney stone. I suspect there was a connection. I caution you about taking very large daily doses.kw202 wrote:Here's a question: If I'm dosing vitamin D at 10000 IU a day... what else should I be taking to compensate? I'm also taking about 300mg of magnesium. Should I also be taking K2? How much?
From Dr. Mercola's newsletter: "What You Need to Know about Vitamin K2, D and Calcium"kw202 wrote:Here's a question: If I'm dosing vitamin D at 10000 IU a day... what else should I be taking to compensate? I'm also taking about 300mg of magnesium. Should I also be taking K2? How much?
He interviews Dr. Kate Rheaume-Bleue (15 min): https://www.youtube.com/watch?v=ET_2w9OOdtY#t=16If you take oral vitamin D, you also need to take vitamin K2. Vitamin K2 deficiency is actually what produces the symptoms of vitamin D toxicity, which includes inappropriate calcification that can lead to hardening of your arteries
I do not know that my kidney stone was due to my high, long-term vitamin D supplementation. I suspect there was a connection. As most people who connect events occurring at the same time, I ascribed the kidney stone event to the only change I had made, i.e. D3 supplementation.vilnietis wrote:lyndacarol,
how do you know that kidney stones are due to vitamin D supplementation? Following your logic people cannot go outside the house during daytime. Everyone knows that people are able to get 10,000IU from sunlight in half an hour. Sunlight will also lead to calcification.
I would now encourage anyone taking high doses of vitamin D3 supplements for an extended period of time to have the doctor monitor his/her urinary calcium.CONCLUSIONS:
Among stone formers with vitamin D deficiency, a limited course of vitamin D repletion does not seem to increase mean urinary calcium excretion, although a subset of individuals may have an increase. These data suggest that vitamin D therapy, if indicated, should not be withheld solely on the basis of stone disease, but 24-hour urinary calcium excretion should be monitored after repletion.
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