fyi re a familiar cofactor. blame anon for this ;D
fwiw, here are three of the first four google scholar results for a seach on zinc calcitriol:
Zinc modulates mononuclear cellular calcitriol metabolism in peritoneal dialysis patientshttp://www.ncbi.nlm.nih.gov/pubmed/8731107
the effect of zinc on mononuclear cellular cytokine and calcitriol production is mediated through different pathways.
Zinc nutritional status modulates the response of 1,25-dihydroxycholecalciferol to calcium depletion in ratshttp://europepmc.org/abstract/MED/16194 ... 1Mz4nwo.22
1,25(OH)2D increased in both groups, but was higher in the zinc-replete than the zinc-depleted group at the end of the experiment. ... We conclude zinc depletion diminishes the response of 1,25(OH)2D to calcium depletion in rats.
Zinc nutritional status modulates the 1,25-(OH)2D. Response in uremic ratshttp://europepmc.org/abstract/MED/1819762
There was a significant effect of renal function, zinc nutritional status, and the interaction of these factors in accounting for differences in mean 1,25-(OH)2D levels.
not to mention:
Possible alterations of the in vivo 1,25(OH)2D3 synthesis and its tissue distribution in magnesium-deficient rats.http://europepmc.org/abstract/MED/7669505
We found that magnesium deficiency produced a decrease of both the in vivo synthesis of 3H-1,25(OH)2D3 and the binding of the radioactive hormone to bone tissue.
Hypomagnesemia and the parathyroid hormone-vitamin D endocrine system in children with insulin-dependent diabetes mellitus: Effects of magnesium administrationhttp://www.sciencedirect.com/science/ar ... 760580486X
All patients were given magnesium orally (6 mg/kg daily of elemental magnesium) for up to 60 days. During treatment, serum magnesium, total and ionized calcium, intact PTH, calcitriol, and osteocalcin concentrations significantly increased, reaching control values. ... These data suggest that magnesium deficiency plays a pivotal role in altering mineral homeostasis in insulin-dependent diabetes mellitus.
my approach: no meds so far - just nutrient-dense anti-inflammatory whole foods, and supplements where needed
info: www.whfoods.com, www.nutritiondata.com