Search found 541 matches
- Mon Jun 03, 2024 8:33 am
- Forum: General Discussion
- Topic: Science Pinpoints Nutrients Crucial to Brain Health
- Replies: 5
- Views: 469
Re: Science Pinpoints Nutrients Crucial to Brain Health
She is on a lactose - gluten free diet and with no food that has intolerance to, according to her ELISA test. A Mediterranean like diet but reach in proteins and cholesterol/healthy fats. Her blood tests are much better than before her MS, and the supplements, especially when she takes many antioxid...
- Sun Jun 02, 2024 6:51 am
- Forum: General Discussion
- Topic: Science Pinpoints Nutrients Crucial to Brain Health
- Replies: 5
- Views: 469
Re: Science Pinpoints Nutrients Crucial to Brain Health
I give to my wife 3 caps per day Phosphatidylserine since the first days of her MS along with Q10, ALA, AlCar, Omega 3!
Later we added lots of supplements that help too
Later we added lots of supplements that help too
- Fri May 31, 2024 2:56 am
- Forum: General Discussion
- Topic: How Epstein-Barr virus triggers multiple sclerosis
- Replies: 5
- Views: 777
Re: How Epstein-Barr virus triggers multiple sclerosis
Shikonik and Apigenin, two natural supplements inhibit inflammasome and Epstein-Barr virus reactivation:
https://www.sciencedirect.com/science/a ... 4223001778
As oleuropein does:
https://assets-eu.researchsquare.com/fi ... b40e22.pdf
https://www.sciencedirect.com/science/a ... 4223001778
As oleuropein does:
https://assets-eu.researchsquare.com/fi ... b40e22.pdf
- Fri May 31, 2024 12:52 am
- Forum: General Discussion
- Topic: How Epstein-Barr virus triggers multiple sclerosis
- Replies: 5
- Views: 777
Research identifies mechanisms for selective multiple sclerosis treatment strategy
Basic science research but interesting in that it provides some explanation of the MS EBV link and a potential target pathway for treatment. Interestingly this pathway is likely to be less immunosuppressive! https://medicalxpress.com/news/2024-05-mechanisms-multiple-sclerosis-treatment-strategy.html...
- Wed May 29, 2024 2:58 am
- Forum: General Discussion
- Topic: New adaptive clinical trial aims to reverse neurological damage caused by progressive multiple sclerosis
- Replies: 0
- Views: 146
New adaptive clinical trial aims to reverse neurological damage caused by progressive multiple sclerosis
The first-ever adaptive clinical trial for Australians living with MS will seek to reverse neurological damage caused by progressive multiple sclerosis. With an initial $4 million in funding, the trial, commencing in January 2024, will enable researchers to investigate the potential benefits of seve...
- Mon May 20, 2024 1:52 pm
- Forum: General Discussion
- Topic: Bazedoxifene, an osteoporosis medicine for women, as Remyelinating agent
- Replies: 8
- Views: 2118
Re: Bazedoxifene, an osteoporosis medicine for women, as Remyelinating agent
Selective Estrogen Receptor Modulator Enhances CNS Remyelination Independent of Estrogen Receptors (in vivo)
Free full text.
https://www.researchgate.net/publicatio ... _Receptors
Free full text.
https://www.researchgate.net/publicatio ... _Receptors
- Mon May 20, 2024 8:27 am
- Forum: General Discussion
- Topic: Lipoic acid and carvedilol promote remyelination in cuprizone model
- Replies: 6
- Views: 558
Re: Lipoic acid and carvedilol promote remyelination in cuprizone model
More or less half quantity of Na-R-ALA is needed compared to R-ALA or R/S-ALA, perfect!NHE wrote: ↑Mon May 20, 2024 6:18 am Here's a study I posted a while back. It found increased Cmax and AUC for Na-R-Lipoate vs. R-Lopic Acid.
viewtopic.php?t=31875
- Mon May 20, 2024 1:37 am
- Forum: General Discussion
- Topic: Lipoic acid and carvedilol promote remyelination in cuprizone model
- Replies: 6
- Views: 558
Re: Lipoic acid and carvedilol promote remyelination in cuprizone model
20 mg/kg/d is too much ALA and costs a lot. They don't mention what type of ALA they use. Unless a paper specifies R-Lipoic Acid or Na-R-Lipoate, I think it's safe to assume that Alpha Lipoic Acid refers to racemic R/S-Lipoic Acid. I assume with less quantity of Na-R-Lipoate we have the same result...
- Sun May 19, 2024 1:19 pm
- Forum: General Discussion
- Topic: Lipoic acid and carvedilol promote remyelination in cuprizone model
- Replies: 6
- Views: 558
Re: Lipoic acid and carvedilol promote remyelination in cuprizone model
20 mg/kg/d is too much ALA and costs a lot.
They don't mention what type of ALA they use.
We all know that sodium salt of ALA especially in caps form is more stable, less sensitive to heat and light and has increased bioavailability, I don't know by how much though!
They don't mention what type of ALA they use.
We all know that sodium salt of ALA especially in caps form is more stable, less sensitive to heat and light and has increased bioavailability, I don't know by how much though!
- Mon May 13, 2024 10:52 am
- Forum: General Discussion
- Topic: Ancient Medicinal Blessed Thistle May Regenerate Injured Nerves!
- Replies: 1
- Views: 333
Re: Ancient Medicinal Blessed Thistle May Regenerate Injured Nerves!
By searching the Cnicin (from Blessed Thistle) I found that Parthenolide (from Feverfew) promotes also nerve regeneration:
https://scholar.google.gr/scholar?q=par ... i=scholart
https://scholar.google.gr/scholar?q=par ... i=scholart
- Mon May 13, 2024 10:37 am
- Forum: General Discussion
- Topic: Pantothenic Acid – Vitamin B5
- Replies: 2
- Views: 645
Re: Pantothenic Acid – Vitamin B5
Wife takes daily among other supplements, 1 lozenge coenzymated B complex by Source Naturals (contains 25mg Calcium-D-Pantothenate), and 4 lozenges coenzymated B1 (25mg cocarboxylase each).
25mg coenzymated is equivalent to ~500mg of vitamin
25mg coenzymated is equivalent to ~500mg of vitamin
- Sun May 12, 2024 8:48 pm
- Forum: General Discussion
- Topic: A NEW WAY TO PROMOTE REMYELINATING
- Replies: 2
- Views: 327
- Sun May 12, 2024 8:46 pm
- Forum: General Discussion
- Topic: A NEW WAY TO PROMOTE REMYELINATING
- Replies: 2
- Views: 327
A NEW WAY TO PROMOTE REMYELINATING
Remyelination failure in diseases like multiple sclerosis (MS) was thought to involve suppressed maturation of oligodendrocyte precursors; however, oligodendrocytes are present in MS lesions yet lack myelin production. We found that oligodendrocytes in the lesions are epigenetically silenced. Develo...
- Sun May 12, 2024 8:44 pm
- Forum: General Discussion
- Topic: Nearly $650k awarded to advance potential remyelination drug IFB-048
- Replies: 0
- Views: 272
Nearly $650k awarded to advance potential remyelination drug IFB-048
The National Multiple Sclerosis Society has awarded Inflectis BioScience a grant valued at $649,601 to advance the preclinical development of IFB-048, the company’s experimental treatment to promote myelin repair in multiple sclerosis (MS). “This grant along with the support from the Society are a t...
- Sun May 12, 2024 8:42 pm
- Forum: General Discussion
- Topic: Ancient Medicinal Blessed Thistle May Regenerate Injured Nerves!
- Replies: 1
- Views: 333
Ancient Medicinal Blessed Thistle May Regenerate Injured Nerves!
A component in blessed thistle may have the potential to repair damaged nerves, investigators have found. Cnicin promotes functional nerve regeneration Phytomedicine. 2024 Apr 14:129:155641. https://www.sciencedirect.com/science/article/pii/S0944711324003003 Background : The limited regenerative cap...