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Following is some research I posted on the thread concerning the association between vitamin B12 and an increased risk of cancer. "The absorption of vitamin B12 is an amazingly complex process. A recent study from Norway may be an indication that it might be best if we don’t interfere with this...

I think the important thing is to restore your body's ability to metabolize vitamin B12. Numerous studies have shown that MS patients lack vitamin B12 due to an inability to properly metabolize the vitamin. For instance, researchers in the following study found that MS patients had significantly low...

Hi Ann, I would not recommend you supplement with vitamin B12. Research shows that patients with MS are unable to properly metabolize the vitamin. Adding supplemental vitamin B12 to your bloodstream will not correct this. It may however greatly increase your risk of cancer. Cancer cells put out extr...

Hi Ann, Patients with MS have elevated levels of a cytokine called tumor necrosis factor. I explain why on this thread: http://www.thisisms.com/forum/general-discussion-f1/topic22806.html Following is one study on the association between tumor necrosis factor (TNF) and SIPR2. The researchers conclud...

I am not sure I even mentioned endothelial cells in my post, but I agree that endothelial cells can be damaged in various ways. In MS though, the research shows they are being damaged and the blood-brain barrier breakdown is occurring in a "specific" manner. For instance, in the following ...

The common denominator that all of the diseases I listed share that would increase endothelin-1 is elevated homocysteine. Homocysteine also activates monocytes and macrophages. Following is some information I posted previously on this. Homocysteine increases the expression of the pro-inflammatory ch...

Hi PN~ So sorry you are in the hospital. Yes, you can have elevated serum levels of B12 and low cellular levels if you are supplementing. There really isn't anything you could take in a supplement form that would restore your protease and DNase 1 safely and effectively. It will take some time to hea...

I am going to post the following information on my Facebook page tonight. You can check my profile for the link if you would like to check the page out. NEW MULTIPLE SCLEROSIS STUDY FINDS THAT A POTENT VASOCONSTRICTOR CALLED ENDOTHELIN-1 INHIBITS MYELIN REPAIR/IMPLICATIONS FOR FIBROMYALGIA AND OTHER...

Hi cervocuit~ Protease and DNase 1 originate in the exocrine pancreas. Your body makes your enzymes, which are proteins, just like it makes all of your bodily proteins-by digesting dietary proteins. In order to properly digest proteins, you need sufficient HCL, beneficial bacteria, and of course the...

I think this would be connected to missing enzymes called protease. These enzymes digest dietary proteins. I posted a great deal of information on the association to these missing enzymes and MS on this thread. http://www.thisisms.com/forum/general-discussion-f1/topic22806.html Researchers have alre...

Just as in MS, everything on the list can be traced directly back to the missing enzymes protease and DNase 1. In fact, recent very definitive cerebrospinal fluid studies confirm the involvement of protease in fibromyalgia. The symptoms and scientific findings of fibromyalgia are the same as in MS b...

The same underlying pathological process can result in a different constellation of symptoms and therefore result in a range of eventual diagnoses. For instance, the inability to properly metabolize vitamin B12 would affect each individual differently to some respect. I think this is what might be i...

Due to the inability to properly metabolize vitamin B12, white matter lesions are found in all autoimmune diseases. For instance, in the following study when fifty-eight Sjögren syndrome (SS) patients with neurologic manifestations associated with SS had magnetic resonance imaging (MRI) of the brain...

I think there are two different components to autoimmune disease. There is the immune system component and then there is the nutritional deficiency component, but they are linked by one common denominator-missing enzymes. These missing enzymes bind and transport vitamin B12. The inability to properl...

Here is a picture of one of these NETs. Notice the last paragraph where it states lupus patients lack the enzyme DNase 1. http://www.sciencedaily.com/releases/2010/05/100503161423.htm The formation of these NETs in lupus, MS, and in other autoimmune diseases is not faulty behavior on the part of the...