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Plegridy is easy to administer and for that I was willing to give it a try. I went into major depression and then extreme anxiety as a result...which is the first major side effect listed. For some reason Avonex did not affect me that way at all. I'd rather be off all meds that have this experience ...

I began Plegridy the end of April after 16 years on Avonex. I did well on Avonex until the last year when I had 3 relapses. I switched and began getting depressed which had never happened to me before. I stopped the Plegridy for several weeks but my doctor told me to restart it. I now have extreme a...