Search found 1494 matches

by Scott1
Sat Jul 04, 2020 10:21 pm
Forum: Introductions
Topic: Newly Diagnosed Introduction
Replies: 3
Views: 76

Re: Newly Diagnosed Introduction

Hi, The first thing to do, as Tecfidera is your choice, is to ask for a test for John Cunningham Virus (JCV). If you search for "FDA" and "Tecfidera" you quickly find the FDA notes or go here - https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/204063s014lbl.pdf . As part of the prescribing p...
by Scott1
Thu Jul 02, 2020 11:59 pm
Forum: Undiagnosed
Topic: Plethora of symptoms
Replies: 6
Views: 104

Re: Plethora of symptoms

Hi, Firstly, I think you're seeing the right person. The lack of damage that is typical of MS almost certainly rules out that as the reason you have your symptoms. It doesn't mean you haven't got a neurological problem but it doesn't guarantee that your symptoms are caused by nerve damage. It could ...
by Scott1
Sun Jun 28, 2020 5:09 am
Forum: Undiagnosed
Topic: What to tell my neuro
Replies: 9
Views: 113

Re: What to tell my neuro

Hi, I presume your neurologist was involved in the brain surgery?? We all have 12 cranial nerves. All of them are involved in a range of things. The sensory neurons in those nerves are responsible for altered sensations. Those neurons take the information back to various ares of the brain for proces...
by Scott1
Sat Jun 27, 2020 1:23 am
Forum: Undiagnosed
Topic: Is MS still a possibility? Desperate...
Replies: 9
Views: 157

Re: Is MS still a possibility? Desperate...

Hi Sarah, If you don't have fluctuating blood pressure that's a good thing. The reason I asked was related to your description of "bladder problems". Those issues can have different presentations. For my own benefit, I was checking to preempt scans of the spine. When a patient has damage above T5 (a...
by Scott1
Thu Jun 25, 2020 5:22 am
Forum: Undiagnosed
Topic: Is MS still a possibility? Desperate...
Replies: 9
Views: 157

Re: Is MS still a possibility? Desperate...

Hi Sarah, The neurologist is basically saying there is not sufficient evidence on the MRI to make an MS diagnosis. You are absolutely right that a lumber puncture can be done. It may show bands of protein that indicate MS or it may not. Your problem is the neurologist is a one trick pony so he has p...
by Scott1
Wed Jun 24, 2020 7:08 pm
Forum: Undiagnosed
Topic: Plethora of symptoms
Replies: 6
Views: 104

Re: Plethora of symptoms

Hi, The lesions don't sound something fresh to me. The brain stem and upper spinal cord will be more informative. Nonetheless, I do think you should push for earlier appointments. I won't list how many things can look like MS. It is a lot. The key thing to focus on is that your symptoms are real and...
by Scott1
Wed Jun 24, 2020 4:58 pm
Forum: Undiagnosed
Topic: Plethora of symptoms
Replies: 6
Views: 104

Re: Plethora of symptoms

Hi, I'm not in the NYC area so can't offer local advice. The MRI of your cervical spine should be more telling than of your brain. It's not possible from your message to tell what the lesions you have mean but compression of the trigeminal nerve is definitely painful. How is your vision? Does it see...
by Scott1
Wed Apr 08, 2020 4:49 am
Forum: MS Etiology and Pathogenesis
Topic: This looks important but I need help to understand it.
Replies: 2
Views: 189

Re: This looks important but I need help to understand it.

Hi, It's not quite as groundbreaking as it sounds. Loci is a fancy name for genetic markers and coding genes. If you stretched out a string of DNA it would be massively long. So it can squeeze into a small space it winds around proteins called histones. If the histone has the opposite charge to the ...
by Scott1
Thu Mar 26, 2020 7:02 pm
Forum: MS Etiology and Pathogenesis
Topic: Epstein Bar Virus - A Review of the Epstein Barr Virus in Relationship to MS
Replies: 4
Views: 571

Re: Epstein Bar Virus - A Review of the Epstein Barr Virus in Relationship to MS

Hi, I don't think that there is a contraindication if you take both but I'd check the dosing. You can't cut a slice of butter with a sledgehammer. It is depends what you are trying to attack. Famcyclovir for HSV1 and 2 is fine. It will possibly slow EBV but won't stop it. If its just EBV you are dea...
by Scott1
Thu Mar 26, 2020 4:28 am
Forum: MS Etiology and Pathogenesis
Topic: Epstein Bar Virus - A Review of the Epstein Barr Virus in Relationship to MS
Replies: 4
Views: 571

Re: Epstein Bar Virus - A Review of the Epstein Barr Virus in Relationship to MS

Hi, Famciclovir breaks down into penciclovir in the body. In this form it has a higher intracellular concentration than acyclovir achieves but it doesn’t cause chain termination. Acyclovir and Valacyclovir result in chain termination. It's Chain termination that you want. A woman called Gertrude Eli...
by Scott1
Tue Dec 17, 2019 8:11 pm
Forum: General Discussion
Topic: How concerned should I be
Replies: 4
Views: 300

Re: How concerned should I be

Hi Glenn, I also feel you might be jumping the gun. The simple answer is to take your daughter to a sports medicine doctor. What you've described, so far, sounds like a sensory issue so it make sense to see if a subtle motor issue is involved. You won't find the answer anywhere on the internet. Some...
by Scott1
Fri Oct 25, 2019 10:44 pm
Forum: General Discussion
Topic: At the breaking point with nausea and vertigo
Replies: 4
Views: 577

Re: At the breaking point with nausea and vertigo

Hi,

I had that bug many years ago. What you describe reminds me of it. The test is simple.
When you throw up, if it has a lot a bile I'd really do the test.

Regards,
by Scott1
Wed Oct 23, 2019 4:02 pm
Forum: General Discussion
Topic: At the breaking point with nausea and vertigo
Replies: 4
Views: 577

Re: At the breaking point with nausea and vertigo

Hi Chris,

Have you been tested for heliobacter Pylori?
Do you think you're more likely to be ill given certain circumstances or is it totally random?
What makes you think vertigo is part of it?
Did it start as something that occassionally happened or is it a sudden massive onslaught?

Regards,
by Scott1
Sun Oct 06, 2019 11:24 pm
Forum: General Discussion
Topic: SPMS How often do you see your doctor
Replies: 7
Views: 993

Re: SPMS How often do you see your doctor

Hi, I'm 62 so I am outside the group you have specifically asked. How you described the frequency and nature of your interactions with doctors did disturb me. The impression I have is you have been given a superficial level of treatment and then been thrown in the "too hard" basket. Whilst many of u...
by Scott1
Tue Oct 01, 2019 10:27 pm
Forum: General Discussion
Topic: Help for muscle spasms in legs
Replies: 2
Views: 588

Re: Help for muscle spasms in legs

I used to get massive leg cramps below the knee for a long time. Then I stumbled on something called Periformis syndrome. Essentially, the periformis muscle squeezes the sciatic nerve and the spasm rips down the leg. Lying on your hip or buttock whilst sleeping will trigger it. It took a couple of g...

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