Search found 1025 matches

by Leonard
Thu Dec 24, 2020 8:31 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: Theoretical Immunology

This very recent article is very interesting and would seem to be fully aligned with the thinking on this thread: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691656/ Integrate it all, and we arrive at a total break-through. It is a new theory of evolution and the important role of viruses therein,...
by Leonard
Mon Dec 14, 2020 6:32 am
Forum: General Discussion
Topic: Focus on the gut-brain axis
Replies: 82
Views: 14937

Re: Focus on the gut-brain axis

the true value of this last study lies in the fact that it was done with a very wide group of people from all over the world. I think the interaction between brains and the rest of the body including the gut is regulated via the idiotypic regulatory network and the immune homunculus. see for instanc...
by Leonard
Thu Dec 10, 2020 12:48 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: Theoretical Immunology

The thinking in this recent article is completely aligned with the above thinking. And it offers hope that some day there may be an effective therapy for us. It talks about the 'holy grail' for the reversal or abrogation of autoimmunity. https://www.tandfonline.com/doi/full/10.1080/21645515.2019.159...
by Leonard
Fri Nov 27, 2020 8:36 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: Theoretical Immunology

After my encounters with the immunologists and some material I received from Russian academics, my thinking on autoimmunity has progressed. I see no reason to withhold you the latest thinking (update 9 Jan): https://drive.google.com/file/d/1HJHPDMrdmPKnG5XbGNpJElHRMP5kZLMk/view?usp=sharing I hope no...
by Leonard
Wed Oct 07, 2020 9:18 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: Theoretical Immunology in a Global Crisis

On the basis of the above work and some further input, I prepared the attached draft paper on autoimmunology. It complements the above document on Theoretical Immunology. https://drive.google.com/file/d/18EsiUx0SCL9ZDoCIfMvHiUNJCpQDYc9F/view?usp=sharing For many professionals, after some initial ent...
by Leonard
Sun Sep 13, 2020 7:11 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: Theoretical Immunology in a Global Crisis

Hi Scott, I don't think it would be the appropriate thing to do to share the video of the presentation here. Sorry for that. I normally attach great value to openness, but in this case maybe better not. We need these people for our cause. I believe ongoing discussions are best held in the private sp...
by Leonard
Sat Aug 22, 2020 12:45 am
Forum: General Discussion
Topic: An atlas on risk factors
Replies: 1
Views: 192

Re: An atlas on risk factors

Read my thesis on https://www.thisisms.com/forum/viewtopic.php?f=1&t=15188&start=900#p260052 for a broader perspective on things. This Swedish atlas is kindergarten stuff just adding to the confusion. A new global cognition is developing outside traditional circles, on the Internet, in weekly meetin...
by Leonard
Fri Aug 07, 2020 7:52 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: Theoretical Immunology in a Global Crisis

On the basis of the last dozen postings or so, I started to put together a document, a sort of a thesis if you wish. But then, after I collated the postings, I felt a need to add other things where there were holes or where things got insufficient attention. With that, unfortunately, the document go...
by Leonard
Thu Jun 04, 2020 3:56 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: A new concept for MS and other autoimmune diseases

Theoretical Immunology and Chronic Disease A New Horizon for Thinking [/size] Biological life on earth has evolved over several billion years on the basis of relatively stable DNA double helix structures. The development of the directly autocatalytic mechanisms fundamental to living systems began w...
by Leonard
Sun May 10, 2020 2:13 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: A new concept for MS and other autoimmune diseases

In the years prior to my MS diagnosis and the major flare up, I had an agitated skin in the neck when shaving. I remember that a doctor from my employer where I was for an annual check up suggested to start using an after shave. [Post script: Now that my memory comes back, I also had a stiff neck an...
by Leonard
Sat May 09, 2020 8:34 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: A new concept for MS and other autoimmune diseases

Critics might argue that herpes is a double stranded DNA virus and that it may not unravel that easily in the cellular machinery. And therefore that interaction with the HERV resulting in a repackaging of RNA material is not obvious. But it has been known for some time that herpes viruses integrate ...
by Leonard
Fri May 01, 2020 7:22 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: A new concept for MS and other autoimmune diseases

I think that after my 10,000 hours I am getting into the flow of things. I am sure this is not an immediate solution for us or for MS but to know what it is is the first step towards prevention and effective therapies. Based on the last few pages of this thread, the new grand theory might now look a...
by Leonard
Fri May 01, 2020 7:04 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: A new concept for MS and other autoimmune diseases

I was looking through the pile of papers that I collected in recent years and found interesting material on the HERV. It is the missing piece that puts it all together. I then drafted the following text: Autoimmunity: viral recombination on the edge of the self [/size] Over many millions, perhaps ev...
by Leonard
Mon Mar 16, 2020 3:24 am
Forum: General Discussion
Topic: Coronavirus (COVID-19) Research
Replies: 167
Views: 23719

Re: Coronavirus (COVID-19): What You Need To Know

Australian researchers claim two existing drugs could 'cure' COVID-19
https://www.dailymail.co.uk/news/articl ... virus.html
by Leonard
Mon Mar 02, 2020 12:04 am
Forum: General Discussion
Topic: Theoretical Immunology
Replies: 917
Views: 235111

Re: A new concept for MS and other autoimmune diseases

A new grand theory on health and disease ... might now look a bit as follows: 1. It all starts with a viral homeostasis Redox biology is fully intertwined, multiple signaling mechanisms, pathogenic & beneficial effects of oxidative stress, autoimmunity 2. Cellular fitness: a decisive factor between...

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