This Is MS Multiple Sclerosis Knowledge & Support Community

Thanks Dej.

Thanks for the info Ru. I hope it isn't something that will delay it for too long. They really messed up though because now they might not be the first oral med on the market.

I've never mentioned it to anyone but if Jamie's MS progressed, Cladribine is what I'm most interested in of the options to be available in the near future. Her neuro in the Tovaxin clinical trial was trained by Kurtzke at Georgetown and the first thing she told us, almost seemed to be bragging, wa...

Yes Bob, I had 31 infusions and I just didn't feel good taking it with all the new PML cases cropping up here and there. Copaxone stings like heck but it works ok for me. There's been a setback with Cladribine since they somehow messed up the application with the FDA but it should still come out in ...

I just spoke to my MS neuro and I'll be starting Copaxone again as soon as the insurance approval comes through and they send it out to me. I did ok on it and I can take it until Cladribine is approved. It wouldn't make sense to start Tysabri again for a short time then have to take a drug holiday b...

It's been a long time since I've put much thought into it, so the exact specifics don't come to mind but, if you'll remember, calling in interested participants of past clinical trials isn't a departure from what Opexa has done in the past in earlier extension trials Dr. Wynn's advice to me was tha...

I'll be going for a job interview soon for a job that starts training on Dec. 3rd. If I don't get that job, or another one, I'll be there as long as there isn't a blizzard, lol. You know how N. Illinois can be, autumn one day, dead winter the next.

This is the one I'm sort of thinking about, so I was interested just in case you knew.

What are the release dates for these drugs? Did it say March for Cladribine? I couldn't tell when reading the link.

When will it be? I might be able to come depending on several things out of my control right now. It sounds like fun though! And we have a GPS that could get me there and back. I don't know if I could talk anyone into spending the day doing this though, to go along with me.

I was thinking about doing this since last month and after this past week's events with Biogen, it's what I had to do. He said that a minimum "drug holiday" would be three months since that's how long it takes to clear from your system. He also said he has no way of knowing if this will he...

We just got home and I chose not to get my infusion today. The neuro spoke to me for about an hour. I'm going to go back in three months and talk about whether I want to go back on Tysabri, or go on something else. I'll check back in later with more details. I have another appt this afternoon and wo...

An excerpt from the linked article that Prof8 just posted: [Updated comment from Biogen Idec.] There isn’t any data that suggests imposing a drug holiday would reduce the risk of patients getting PML, but there is data that shows symptoms of multiple sclerosis return quickly once patients quit takin...

Youre not helping people that need Tysabri and know there's risk such as myself. You might not make that comment if you'd had 30 infusions and wondered each month if you're at a higher risk of PML, or if it were your child, or spouse? Think about it. Do we want to be sheep? Or make them accountable...

Someone at the Tysabri support center told me yesterday that they believe that the average for disease activity to resume is about six months. That's why I'm thinking six months for a break. That's an interesting comment from Biogen, Wiz. I wonder how they came up with 6 months vs 8 months or even ...

I get my 32nd infusion tomorrow. I'm going to ask my neuro his opinion on the risks and if he thinks they're greater than 1:1000 now. I'm also going to talk to him about taking a break. I'm 99% sure that's what I want unless he can give me a good enough reason why he thinks that's a bad idea. Like y...