Search found 252 matches

by BioDocFL
Fri Jan 27, 2012 11:33 am
Forum: General Discussion
Topic: issue on autoimmune disease hypotheses
Replies: 0
Views: 1192

issue on autoimmune disease hypotheses

About a year ago, LyndaCarol suggested we have a forum on multiple sclerosis hypotheses. I guess that didn't happen but it seemed like autoimmune disease hypotheses would be a good topic for a journal to cover. The journal, Clinical Reviews in Allergy & Immunology, has just published an issue (Feb. ...
by BioDocFL
Mon Jan 23, 2012 4:51 pm
Forum: General Discussion
Topic: A question for US Republicans with MS
Replies: 9
Views: 1173

Re: A question for US Republicans with MS

I was expecting Michelle Obama to be involved in promoting MS research since her father had suffered from it. I am glad she has been working to support military families though.
by BioDocFL
Thu Nov 17, 2011 4:48 pm
Forum: General Discussion
Topic: MS slideshow from WebMD
Replies: 0
Views: 918

MS slideshow from WebMD

Don't know if this has been posted on ThisIsMS before but I thought it was worth noting.


http://www.webmd.com/multiple-sclerosis ... s-overview


Wesley
by BioDocFL
Wed Nov 16, 2011 8:57 am
Forum: General Discussion
Topic: MSIF concerned over rise in incidence of MS in India
Replies: 2
Views: 1182

Re: MSIF concerned over rise in incidence of MS in India

Bhopal-like contamination sites could be a possible explanation. Over 500,000 people were harmed from exposure to the accident (release of methyl isocyanate gas in 1984) and >3000 died soon after the exposure. Bhopal is in the exact center of India. Of course cyanates can damage nerves. I would also...
by BioDocFL
Sat Jan 15, 2011 11:26 am
Forum: General Discussion
Topic: One for Biodocfl
Replies: 2
Views: 1419

Dignan, Thanks for posting that. I am feeling more confident about my polyamine hypothesis over the past few years. I presented it at a Sjogren's syndrome meeting in Brest, France in 2009 and, based on that, I was invited to present it in Zurich this past October at an international rheumatoid arthr...
by BioDocFL
Mon Jan 10, 2011 7:23 pm
Forum: Suggestions
Topic: Any possibility of new forum: Hypothesis – MS Not Autoimmune
Replies: 9
Views: 5564

That's an excellent idea. I'll try to come up with some articles for it too. We might want to cover the shortcomings of EAE as a model for MS, if that hasn't already been covered.

Wesley
by BioDocFL
Wed Nov 24, 2010 8:32 am
Forum: General Discussion
Topic: Possible cause and treatment for MS discovered
Replies: 16
Views: 3301

The acrolein could be coming from elevated polyamines, and the polyamines are elevated because of over-expression of X-linked polyamine genes, spermine synthase and spermidine/spermine-N1-acetyltransferase, at Xp22.1 when X chromosome inactivation is lost in a few cells. This is what I was talking a...
by BioDocFL
Fri Oct 15, 2010 3:39 pm
Forum: General Discussion
Topic: Polyamine hypothesis
Replies: 2
Views: 1518

Thanks. It seems to have survived scrutiny by autoimmune researchers so far and gotten them interested. I am hoping to get a chance to talk at the Epigenetics World Congress in Boston next April to put it in front of epigenetics researchers. So I will have to add a bit more about autoimmune disease ...
by BioDocFL
Thu Oct 14, 2010 4:35 pm
Forum: General Discussion
Topic: Polyamine hypothesis
Replies: 2
Views: 1518

Polyamine hypothesis

Six years ago we had a discussion about the polyamine hypothesis I have been developing. Since then I have kept relatively quiet about it here but I continued working on it. I have developed it a lot further, but it is still centered around the same concepts as were discussed. Last year I presented ...
by BioDocFL
Tue Sep 07, 2010 3:53 pm
Forum: General Discussion
Topic: Life Insurance
Replies: 13
Views: 1781

The National Multiple Sclerosis Society has some information on insurance. Perhaps there is something useful for you there.

http://www.nationalmssociety.org/living ... index.aspx
by BioDocFL
Tue Jun 29, 2010 3:21 pm
Forum: General Discussion
Topic: Moving to Clearwater FL & looking for MS Doc recommendat
Replies: 3
Views: 1442

Tacco, Welcome to the Canadian suburbs. The University of South Florida in Tampa is about a 40-50 minute drive from Clearwater (from Clearwater Beach it is probably a bit longer). You might want to check out the USF Neurology dept. One of the doctor's there seems to get very good reviews from his pa...
by BioDocFL
Fri Jun 18, 2010 8:51 am
Forum: General Discussion
Topic: DRY mouth!
Replies: 8
Views: 5142

Have your doctor check for secondary Sjogren's syndrome. That could explain dry eyes and mouth, but there could be other explanations, such as a new medicine or change in your diet.
by BioDocFL
Mon Apr 19, 2010 9:03 am
Forum: General Discussion
Topic: Volcano advice please
Replies: 4
Views: 1323

Thanks. It sounds like there might be some opening of airports soon since the test flights have all gone well. My wife is going with me. We will travel light so we can easily carry everything. We are supposed to fly into Munich and then we have first class tickets for the train to Ljubljana but they...
by BioDocFL
Sun Apr 18, 2010 2:48 pm
Forum: General Discussion
Topic: Volcano advice please
Replies: 4
Views: 1323

Volcano advice please

Coverage in Florida of the Icelandic volcano does not give much detail or forecasting about the mess and particularly about traveling to Europe. I imagine it is very difficult to predict. I am wondering if anyone has found a good source for information about the volcano, ash cloud predictions, and e...
by BioDocFL
Sat Apr 17, 2010 5:25 am
Forum: General Discussion
Topic: Is there a relationship between MS and Breast Cancer
Replies: 12
Views: 7872

Do either of you know what type breast cancer you had?

I believe there could be a connection between basal-like breast cancer and autoimmune diseases.

Wesley