Mice that have their jugular veins ligated to simulate CCSVI do not develop any brain inflammation or demyelination, suggesting yet again that ‘veinous insufficiency’ does not cause multiple sclerosis.
Researchers from Harvard Medical School in the US took 20 mice, ligated both jugular veins and observed them for six months.
Fifteen control mice were given a sham ligation procedure and another eight were induced with experimental autoimmune encephalomyelitis as negative controls.
Despite CT venography confirming the ligation produced hemodynamic changes, MRI demonstrated there were no signs of blood-brain barrier breakdown or neuroinflammation.
In addition, cytometry and histopathology showed ligation didn’t result in any increase in inflammatory cell populations or demyelination.
Moreover, no clinical signs were observed in any of the ligated mice.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/2944
This data is just overwhelming. This evidence gives us reason to pack up and go home.
I am going to throw away all my catheters and use my balloons for my grandson's birthday party.
On the other hand.... it took me two minutes to find out shockingly that the mouse brain IS DIFFERENT FROM THE human brain. NOt to mention that we don't even look like mice (any longer) and we stopped acting like mice sometime around 2007
The cerebral venous drainage of the mouse is not like that of the human. The major vein that drains the mouse intracranial circulation, is the retroglenoid vein that is a continuation of the transverse sinuses. It does not even exist in humans except as a rare anomaly. The internal jugular veins and the vertebral veins are not the major output.
Is this published in a journal? if so, which journal published this. what are the affiliations of the authors? who sponsored this research
Early April Fools