frodo wrote:Thanks. That's what I was thinking, but on the other hand, I had never heard about WM lesions just for ageing, and things like NAWM also sounds very MS-like. It is interesting that the same proceses of MS appear in old people (assuming that NAWM has the same meaning in both cases).
The researchers estimated that each 1% increase in pulse wave velocity at baseline was associated with a 0.3% increase in the volume of white matter hyperintensities 7 years later.
They hypothesized that the difference in stiffness between the highly elastic aortic arch and the blood vessels leading to the brain might have a protective effect on the cerebral microvasculature, by causing some of the pressure to be reflected.
That notion would imply that higher pulse wave velocity (a result of greater stiffness) would reduce the protective effect.
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