The other threads on vitamin D in pregnancy and the effect of the birth-month are related to the subject mattergeneral-discussion-f1/topic21166.htmlgeneral-discussion-f1/topic21172.html
But the researchers have it all mixed up.
Of course, the risk of MS relates to the month of birth.
What is important here is the vitamin D available in the blood stream during the main phases of cellular growth.
The cell composition (and number of vit D gates) is directly related to the vit D available in the blood,
that is of the mother (fetus) and the own blood stream (adolecence).
During the Summer, the vit D concentration will be higher (matter of sun exposure) where cells built will have more vit D gates..
The vitamin D relationship itself is more complex and in the minds of people often convoluted.
This needs to be unravelled.
There is the matter of the cell composition (see above).
Vit D supplementation then is probably affecting the gut flora (and peptides for natural antibiotics).
Further, the vit D metabolism in the blood may in some way be related to the gut concentration
but there is an advanced regulatory loop as well between active and non-active vit D,
and that loop is influenced by disease activity (the reverse path from active to non-active).
In this same context, it is unclear to me whether there is a difference between the own body generated vit D and the administered D; there are indications that there is a difference.. (so we should not block the sun, neither the mother nor the growing child; may explain tthe sharp rise in immune diseases...)
When the Vit D receptor and other receptors are enabled again, 1000 or more genes will be transcribed again,
with effects on the organs, and also the nerves..
And the body will take metabolic control again..
In my case, the bad gut developed already around 1997/98 while I was diagnosed with MS in 2004.
This gives an indication of the time spans involved; it took years to disable the VDR.
when the gut flora is restored, the VDR and other receptors are enabled again, it may take a year or more to re-establish metabolic control and improve nerve condition..