PM10
Re: PM10
2024 Jun 13
Predicting the daily number of patients for allergic diseases using PM10 concentration based on spatiotemporal graph convolutional networks
https://pubmed.ncbi.nlm.nih.gov/38870112/
Predicting the daily number of patients for allergic diseases using PM10 concentration based on spatiotemporal graph convolutional networks
https://pubmed.ncbi.nlm.nih.gov/38870112/
https://www.eboro.cz
Re: PM10
2024 Jun 1
Department of Occupational Therapy, Soonchunhyang University, Republic of Korea
Particulate Matter-Induced Neurotoxicity: Unveiling the Role of NOX4-Mediated ROS Production and Mitochondrial Dysfunction in Neuronal Apoptosis
https://pubmed.ncbi.nlm.nih.gov/38892302/
Abstract
Urban air pollution, a significant environmental hazard, is linked to adverse health outcomes and increased mortality across various diseases. This study investigates the neurotoxic effects of particulate matter (PM), specifically PM2.5 and PM10, by examining their role in inducing oxidative stress and subsequent neuronal cell death.
Department of Occupational Therapy, Soonchunhyang University, Republic of Korea
Particulate Matter-Induced Neurotoxicity: Unveiling the Role of NOX4-Mediated ROS Production and Mitochondrial Dysfunction in Neuronal Apoptosis
https://pubmed.ncbi.nlm.nih.gov/38892302/
Abstract
Urban air pollution, a significant environmental hazard, is linked to adverse health outcomes and increased mortality across various diseases. This study investigates the neurotoxic effects of particulate matter (PM), specifically PM2.5 and PM10, by examining their role in inducing oxidative stress and subsequent neuronal cell death.
https://www.eboro.cz
Re: PM10
2024 Jun 18 Division of Pathophysiology, Institute of Physiology and Pathophysiology, Medical Faculty, Johannes Kepler University, Linz, Austria
Airborne Aluminum as an Underestimated Source of Human Exposure: Quantification of Aluminum in 24 Human Tissue Types Reveals High Aluminum Concentrations in Lung and Hilar Lymph Node Tissues
https://pubmed.ncbi.nlm.nih.gov/38888518/
..Al was continuously found in PM2.5 and PM10 fine dust particles over 7 years in Upper Austria
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MS
2018 Aug 18
Aluminium in Brain Tissue in Multiple Sclerosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121957/
Abstract
Multiple sclerosis (MS) is a devastating and debilitating neurodegenerative disease of unknown cause. A consensus suggests the involvement of both genetic and environmental factors of which the latter may involve human exposure to aluminium. There are no data on the content and distribution of aluminium in human brain tissue in MS. The aluminium content of brain tissue from 14 donors with a diagnosis of MS was determined by transversely heated graphite furnace atomic absorption spectrometry. The location of aluminium in the brain tissue of two donors was investigated by aluminium-specific fluorescence microscopy. The aluminium content of brain tissue in MS was universally high with many tissues bearing concentrations in excess of 10 μg/g dry wt. (10 ppm) and some exceeding 50 ppm. There were no statistically significant relationships between brain lobes, donor age or donor gender. Aluminium-specific fluorescence successfully identified aluminium in brain tissue in both intracellular and extracellular locations. The association of aluminium with corpora amylacea suggests a role for aluminium in neurodegeneration in MS.
Airborne Aluminum as an Underestimated Source of Human Exposure: Quantification of Aluminum in 24 Human Tissue Types Reveals High Aluminum Concentrations in Lung and Hilar Lymph Node Tissues
https://pubmed.ncbi.nlm.nih.gov/38888518/
..Al was continuously found in PM2.5 and PM10 fine dust particles over 7 years in Upper Austria
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MS
2018 Aug 18
Aluminium in Brain Tissue in Multiple Sclerosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121957/
Abstract
Multiple sclerosis (MS) is a devastating and debilitating neurodegenerative disease of unknown cause. A consensus suggests the involvement of both genetic and environmental factors of which the latter may involve human exposure to aluminium. There are no data on the content and distribution of aluminium in human brain tissue in MS. The aluminium content of brain tissue from 14 donors with a diagnosis of MS was determined by transversely heated graphite furnace atomic absorption spectrometry. The location of aluminium in the brain tissue of two donors was investigated by aluminium-specific fluorescence microscopy. The aluminium content of brain tissue in MS was universally high with many tissues bearing concentrations in excess of 10 μg/g dry wt. (10 ppm) and some exceeding 50 ppm. There were no statistically significant relationships between brain lobes, donor age or donor gender. Aluminium-specific fluorescence successfully identified aluminium in brain tissue in both intracellular and extracellular locations. The association of aluminium with corpora amylacea suggests a role for aluminium in neurodegeneration in MS.
https://www.eboro.cz
Re: PM10
2024 May 9
Long-term exposure to air pollution on cardio-respiratory, and lung cancer mortality: a systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/38887768/
..We observed positive increased associations between exposure to PM2.5, PM10, black carbon (BC), and nitrogen dioxide (NO2) with all-cause, cardiovascular and respiratory diseases, and lung cancer mortality, but the associations were not significant for nitrogen oxides (NOx), sulfur dioxide (SO2) and ozone (O3).
Long-term exposure to air pollution on cardio-respiratory, and lung cancer mortality: a systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/38887768/
..We observed positive increased associations between exposure to PM2.5, PM10, black carbon (BC), and nitrogen dioxide (NO2) with all-cause, cardiovascular and respiratory diseases, and lung cancer mortality, but the associations were not significant for nitrogen oxides (NOx), sulfur dioxide (SO2) and ozone (O3).
https://www.eboro.cz
Re: PM10
2024 Jun 21
Harvard College, Cambridge, Massachusetts, United States
Comparing traditional and causal inference methodologies for evaluating impacts of long-term air pollution exposure on hospitalization with Alzheimer's disease and related dementias
https://pubmed.ncbi.nlm.nih.gov/38907309/
Harvard College, Cambridge, Massachusetts, United States
Comparing traditional and causal inference methodologies for evaluating impacts of long-term air pollution exposure on hospitalization with Alzheimer's disease and related dementias
https://pubmed.ncbi.nlm.nih.gov/38907309/
https://www.eboro.cz
Re: PM10
2024 Jun 19
Coarse particulate air pollution and mortality in a multidrug-resistant tuberculosis cohort
https://pubmed.ncbi.nlm.nih.gov/38906282/
Conclusion: Long-term exposure to PM2.5-10 poses significant harm among MDR-TB patients, with effects modified by temperature and humidity. Immediate surveillance of PM2.5-10 is crucial to mitigate the progression of MDR-TB severity, particularly due to co-exposures to air pollution and adverse weather conditions.
Coarse particulate air pollution and mortality in a multidrug-resistant tuberculosis cohort
https://pubmed.ncbi.nlm.nih.gov/38906282/
Conclusion: Long-term exposure to PM2.5-10 poses significant harm among MDR-TB patients, with effects modified by temperature and humidity. Immediate surveillance of PM2.5-10 is crucial to mitigate the progression of MDR-TB severity, particularly due to co-exposures to air pollution and adverse weather conditions.
https://www.eboro.cz
Re: PM10
2024 Jun 19
Associations between air pollution and the onset of acute exacerbations of chronic obstructive pulmonary disease: A time-stratified case-crossover study in China
https://pubmed.ncbi.nlm.nih.gov/38906462/
..no significant association was observed for O3.
Interpretation: This study provides robust evidence that short-term exposure to PM2.5 and PM10 was associated with higher odds of AECOPD onset. Individuals who are young, have severe COPD or young COPD, and experience an exacerbation during the cooler seasons may be particularly susceptible.
Associations between air pollution and the onset of acute exacerbations of chronic obstructive pulmonary disease: A time-stratified case-crossover study in China
https://pubmed.ncbi.nlm.nih.gov/38906462/
..no significant association was observed for O3.
Interpretation: This study provides robust evidence that short-term exposure to PM2.5 and PM10 was associated with higher odds of AECOPD onset. Individuals who are young, have severe COPD or young COPD, and experience an exacerbation during the cooler seasons may be particularly susceptible.
https://www.eboro.cz
Re: PM10
2024 Jun 24
Air pollution and kidney cancer risk: a systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/38913266/
Conclusions: Overall, our findings suggest a potential association between exposure to increased levels of PM10 and NO2 and the risk of kidney cancer. These results should nonetheless be interpreted with caution due to the limited number of included studies and their significant risk of methodological bias.
Air pollution and kidney cancer risk: a systematic review and meta-analysis
https://pubmed.ncbi.nlm.nih.gov/38913266/
Conclusions: Overall, our findings suggest a potential association between exposure to increased levels of PM10 and NO2 and the risk of kidney cancer. These results should nonetheless be interpreted with caution due to the limited number of included studies and their significant risk of methodological bias.
https://www.eboro.cz
Re: PM10
2023 Nov 15
Associations between weekly gestational exposure of fine particulate matter, ozone, and nitrogen dioxide and preterm birth in a North Carolina Birth Cohort, 2003-2015
https://pubmed.ncbi.nlm.nih.gov/38912391/
Conclusion: Our results show that increased PM2.5 exposure is associated with an increased risk of PTB across gestational weeks, and these associations persist in multipollutant models with NO2 and/or O3.
Associations between weekly gestational exposure of fine particulate matter, ozone, and nitrogen dioxide and preterm birth in a North Carolina Birth Cohort, 2003-2015
https://pubmed.ncbi.nlm.nih.gov/38912391/
Conclusion: Our results show that increased PM2.5 exposure is associated with an increased risk of PTB across gestational weeks, and these associations persist in multipollutant models with NO2 and/or O3.
https://www.eboro.cz
Re: PM10
2024 Jun 18
Causal Associations of Environmental Pollution and Cardiovascular Disease: A Two-Sample Mendelian Randomization Study
https://pubmed.ncbi.nlm.nih.gov/38911616/
Results: Inverse variance weighted estimates suggested that an SD increase in PM2.5 exposure increased the risk of heart failure (OR = 1.40, 95% CI 1.02-1.93, p = 0.0386). We found that an SD increase in PM10 exposure increased the risk of hypertension (OR = 1.45, 95% CI 1.02-2.05, p = 0.03598) and atrial fibrillation (OR = 1.41, 95% CI 1.03-1.94, p = 0.03461). Exposure to chemical or other fumes in a workplace was found to increase the risk of hypertension (OR = 3.08, 95% CI 1.40-6.78, p = 0.005218), coronary artery disease (OR = 1.81, 95% CI 1.00-3.26, p = 0.04861), coronary heart disease (OR = 3.15, 95% CI 1.21-8.16, p = 0.0183) and myocardial infarction (OR = 3.03, 95% CI 1.13-8.17, p = 0.02802).
Conclusion: This study reveals the causal relationship between air pollutants and cardiovascular diseases, providing new insights into the protection of cardiovascular diseases.
Causal Associations of Environmental Pollution and Cardiovascular Disease: A Two-Sample Mendelian Randomization Study
https://pubmed.ncbi.nlm.nih.gov/38911616/
Results: Inverse variance weighted estimates suggested that an SD increase in PM2.5 exposure increased the risk of heart failure (OR = 1.40, 95% CI 1.02-1.93, p = 0.0386). We found that an SD increase in PM10 exposure increased the risk of hypertension (OR = 1.45, 95% CI 1.02-2.05, p = 0.03598) and atrial fibrillation (OR = 1.41, 95% CI 1.03-1.94, p = 0.03461). Exposure to chemical or other fumes in a workplace was found to increase the risk of hypertension (OR = 3.08, 95% CI 1.40-6.78, p = 0.005218), coronary artery disease (OR = 1.81, 95% CI 1.00-3.26, p = 0.04861), coronary heart disease (OR = 3.15, 95% CI 1.21-8.16, p = 0.0183) and myocardial infarction (OR = 3.03, 95% CI 1.13-8.17, p = 0.02802).
Conclusion: This study reveals the causal relationship between air pollutants and cardiovascular diseases, providing new insights into the protection of cardiovascular diseases.
https://www.eboro.cz
Re: PM10
2024 Jun 22
Associations between particulate matter exposure during pregnancy and executive function of toddlers in a prospective cohort study
https://pubmed.ncbi.nlm.nih.gov/38909950/
Conclusions: PM exposure during the first trimester, especially PM1, has been linked to lower toddler EF performance in toddlers; feeding with breast milk may be a potential protective measure.
Associations between particulate matter exposure during pregnancy and executive function of toddlers in a prospective cohort study
https://pubmed.ncbi.nlm.nih.gov/38909950/
Conclusions: PM exposure during the first trimester, especially PM1, has been linked to lower toddler EF performance in toddlers; feeding with breast milk may be a potential protective measure.
https://www.eboro.cz
Re: PM10
2024 Jun 21
Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Norway
Pregnancy outcomes as related to in utero exposure to air pollution and greenness: The Life-GAP Project
https://pubmed.ncbi.nlm.nih.gov/38919266/
..IQR increases in air pollution exposures during pregnancy were associated with decreased birth weight and the strongest association was seen for PM2.5 (-49g; 95% confidence interval [CI] = -83, -16). However, O3 showed an opposite association. IQR increase in NDVI300m was associated with an increase in birth weight of 25 g (95% CI = 7, 44)
Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Norway
Pregnancy outcomes as related to in utero exposure to air pollution and greenness: The Life-GAP Project
https://pubmed.ncbi.nlm.nih.gov/38919266/
..IQR increases in air pollution exposures during pregnancy were associated with decreased birth weight and the strongest association was seen for PM2.5 (-49g; 95% confidence interval [CI] = -83, -16). However, O3 showed an opposite association. IQR increase in NDVI300m was associated with an increase in birth weight of 25 g (95% CI = 7, 44)
https://www.eboro.cz
Re: PM10
2024 Jun 25
Health impacts of lifestyle and ambient air pollution patterns on all-cause mortality: a UK Biobank cohort study
https://pubmed.ncbi.nlm.nih.gov/38918768/
..The relationship between NOx, PM10, and PM2.5-10 and all-cause mortality was found to be nonlinear (p for nonlinearity < 0.05). Furthermore, no significant interaction was identified between lifestyle and air pollution with respect to all-cause mortality.
Health impacts of lifestyle and ambient air pollution patterns on all-cause mortality: a UK Biobank cohort study
https://pubmed.ncbi.nlm.nih.gov/38918768/
..The relationship between NOx, PM10, and PM2.5-10 and all-cause mortality was found to be nonlinear (p for nonlinearity < 0.05). Furthermore, no significant interaction was identified between lifestyle and air pollution with respect to all-cause mortality.
https://www.eboro.cz