Rituxan (Rituximab)

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Rituxan Prescribing Information

Last post by NHE « Sat Jul 16, 2016 11:33 pm

by NHE » Sat Jul 16, 2016 11:33 pm

Rituxan Prescribing Information

0 Replies

3524 Views

Last post by NHE
Sat Jul 16, 2016 11:33 pm
Rituximab iv and intrathecal with valtrex

Last post by LR1234 « Tue Feb 26, 2019 8:15 pm
Replies: 130
by Anonymoose » Thu Jul 11, 2013 3:11 pm
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Hopefully I am jcv negative so we can proceed in October.

If all goes well, we'll be following standard protocol for ebv-related post transplant...

Last post

Just to update, I went ahead in 2014 taking Rituximab I.V plus I supplement with acyclovir if I feel a bit MSy but I have to say Rituximab has been a...
130 Replies

24993 Views

Last post by LR1234
Tue Feb 26, 2019 8:15 pm
Anyone getting Rituximab for PPMS?

Last post by zen2010 « Fri Feb 09, 2018 5:23 am
Replies: 4
by HUD45 » Wed Nov 02, 2016 6:30 am

First post

I know the FDA has fast tracked the ocrelizumab trials but is there anyone out there with PPMS or SPMS getting the infusions?

I know of someone...

Last post

I am looking for individual opinions of current users

Bump :smile:

I guess many Msers with progressive ms are now taking/have been taking...

4 Replies

4450 Views

Last post by zen2010
Fri Feb 09, 2018 5:23 am
Two weeks post Rituxan

Last post by n1234 « Sun Feb 04, 2018 2:09 pm
Replies: 10
by marcstck » Mon Oct 06, 2008 2:31 pm

First post

Thanks for getting this board up and running. For me, at least, it's a very welcome addition...

Had my second Rituxan infusion on September 19, and...

Last post

I am so glad to read these posts on Rituxan, and thank you all.

I have resisted taking Rituxan, despite my neurologist's enthusiasm. When I inquired...

10 Replies

7580 Views

Last post by n1234
Sun Feb 04, 2018 2:09 pm
Long term effects

Last post by n1234 « Sun Feb 04, 2018 2:04 pm

by n1234 » Sun Feb 04, 2018 2:04 pm

I was recently approved for this medication. I am also on the much younger spectrum in the population of MS.
Does any one have any long term...

0 Replies

1196 Views

Last post by n1234
Sun Feb 04, 2018 2:04 pm
Rituximab ‘superior to all other DMTs...'

Last post by MSUK « Wed Jan 10, 2018 7:48 am

by MSUK » Wed Jan 10, 2018 7:48 am

Rituximab ‘superior to all other DMT in terms of drug discontinuation’ study finds

Scientists have conducted a study that looks at how traditional...

0 Replies

1368 Views

Last post by MSUK
Wed Jan 10, 2018 7:48 am
Time it Takes for Rituxan to Work on MS

Last post by lyndacarol « Sun May 14, 2017 12:23 pm
Replies: 12
by DavidF » Tue Jan 26, 2016 11:45 am

First post

This month I had my first two infusions of Rituxan to treat my RRMS and I am wondering how long before I 'feel better?' Should it be immediate - once...

Last post

Thanks for attention.
I always take a pill vitamin D.
I don't have cancer any more.
My MS is getting worse after chemitropy. After taking vitamin D...

12 Replies

10524 Views

Last post by lyndacarol
Sun May 14, 2017 12:23 pm
Progressive MS trial of Rituximab is stopped

Last post by Anonymoose « Tue Mar 08, 2016 6:44 am
Replies: 2
by MSUK » Tue Mar 08, 2016 1:49 am

First post

Researchers at the National Institutes of Health (NIH) say a small clinical trial of a progressive multiple sclerosis (MS) treatment has been stopped...

Last post

Another interpretation of the study's failure on the Bart's ms blog...

Csf cd20+ B cells were significantly depleted. However, at study dosing...

2 Replies

3383 Views

Last post by Anonymoose
Tue Mar 08, 2016 6:44 am
first infusion (RRMS)

Last post by yammerschooner « Tue Feb 23, 2016 4:51 pm
Replies: 31
by yammerschooner » Mon May 07, 2012 8:59 pm
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First post

just had my first infusion today.

i am still classified as RRMS and am probably doing quite well compared to many people who use these boards....

Last post

Back again, two years later.

I'm still convinced Rituxan is a great medicine. It has arrested my MS progression for almost four consecutive years....
31 Replies

15969 Views

Last post by yammerschooner
Tue Feb 23, 2016 4:51 pm
Side effects from Rituxan?

Last post by kjcm « Mon Dec 28, 2015 11:17 am
Replies: 5
by savvymavi » Mon Jul 28, 2014 5:55 am

First post

I am switching from Tecfidera to Rituxan, due to several new brain & spinal cord lesions despite being on Tecfidera for 13 months. I am wondering...

Last post

Never posted before! I've been on Rituxan for a little over two years. Initially, I received two doses (two weeks apart) per six months as others...

5 Replies

6133 Views

Last post by kjcm
Mon Dec 28, 2015 11:17 am
Rituxan if JC+?

Last post by centenarian100 « Wed Nov 18, 2015 11:44 am
Replies: 2
by lampnerjones » Mon Jun 09, 2014 12:57 pm

First post

I was diagnosed way back in 1991 (22 years ago). I've been incredibly lucky and passed up until about 3 years ago. I'm still mobile but have some...

Last post

In a case series, there were 4 total cases of PML in rheumatoid arthritis treated with rituxan out of 129,000 exposed, suggesting risk of 1/25,000; 1...

2 Replies

5393 Views

Last post by centenarian100
Wed Nov 18, 2015 11:44 am
Need feedback on the use of Rituxan

Last post by Rabies « Sun Nov 15, 2015 5:43 pm
Replies: 13
by ssmme » Thu Oct 30, 2014 6:14 am

First post

My neuro made a personal call to me this morning. My ms is acting particularly aggressive lately. He wants me to start rituxan. Does it work for you?...

Last post

I was diagnosed in Feb this year,although, as usual,with hindsight there were a few warnings for a couple of years prior. Double vision, numbness in...

13 Replies

5826 Views

Last post by Rabies
Sun Nov 15, 2015 5:43 pm
Rituxan: Don't count it out as multiple sclerosis treatment

Last post by MSUK « Tue Oct 13, 2015 5:54 am

by MSUK » Tue Oct 13, 2015 5:54 am

Numerous presentations at the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) meeting made it plain that the anti-CD20...

0 Replies

3053 Views

Last post by MSUK
Tue Oct 13, 2015 5:54 am
"Inexpensive" B cell depletion. Low dose IT rituxan...

Last post by Anonymoose « Mon Jul 13, 2015 9:39 am
Replies: 2
by Anonymoose » Mon Jul 13, 2015 6:30 am

First post

Rapid depletion of B lymphocytes by ultra-low-dose rituximab delivered intrathecally
ABSTRACT
Objective: We are conducting an open-label phase 1b...

Last post

I think the new pms-rituxan studies are exploring the possibility that the treatment failed because IV administration barely penetrates the cns. The...

2 Replies

3454 Views

Last post by Anonymoose
Mon Jul 13, 2015 9:39 am
Rituxan infusion schedule

Last post by Mockmom « Mon May 04, 2015 7:15 pm
Replies: 3
by pballer76 » Sun May 18, 2014 1:33 pm

First post

I'm currently in Gilenya 2 months. I haven't had my blood work to see if I can remain on Gilenya.
I am interested in Rituxan as my neuro has...

Last post

Hi, I had my fist infusion of RITUXAN on 4/27/15. First infusion was 500mg I will have my 2nd infusion on 5/11/15 1000mg, then I go in every 6...

3 Replies

4474 Views

Last post by Mockmom
Mon May 04, 2015 7:15 pm
Immortalized mser B cells produce brain autoantibodies

Last post by Anonymoose « Tue Apr 08, 2014 5:06 pm
Replies: 2
by Anonymoose » Sat Sep 21, 2013 4:34 pm

First post

Couldn't fit a decent title in...sorry if that was a bit misleading.

Immortalised B cell lines from multiple sclerosis patients produce...

Last post

I would be interested to hear the details of the cases in which intrathecal rituxan fails with CNS B cell lymphoma. There are a number of studies,...

2 Replies

3511 Views

Last post by Anonymoose
Tue Apr 08, 2014 5:06 pm
Moving to Rituxan from Tecfidera

Last post by centenarian100 « Tue Apr 08, 2014 2:18 pm
Replies: 9
by xpsychiatricmd » Tue Nov 19, 2013 8:05 am

First post

I have been battling MS since 1999. Finally got diagnosed with SPMS. I have been without a spleen since 1974 due to trauma. Going for Rituxan from...

Last post

Hey guys. I'm sorry to hear that some of you are having trouble getting rituxan in the United States.

Unfortunately, pharmaceutical companies would...

9 Replies

4939 Views

Last post by centenarian100
Tue Apr 08, 2014 2:18 pm
NIH study for SPMS underway on experimental drug Rituximab

Last post by MSUK « Mon Jan 27, 2014 2:06 am

by MSUK » Mon Jan 27, 2014 2:06 am

There are currently no effective treatments for people with secondary-progressive MS who do not experience relapses or who do not have “active”...

0 Replies

3825 Views

Last post by MSUK
Mon Jan 27, 2014 2:06 am
My first Rituxan infusion

Last post by xpsychiatricmd « Wed Nov 27, 2013 7:51 pm
Replies: 6
by AndreaEv » Sat Jul 13, 2013 12:33 am

First post

After waiting 6 months for approval, being on no meds during the wait, I am excited to start the Rituxan. However, I am anxious/nervous about the...

Last post

Hello to all,
I wish I had good news. Went for my first infusion but was told that my insurance, ( AETNA ) would not authorize Rituxan as it is not...

6 Replies

5302 Views

Last post by xpsychiatricmd
Wed Nov 27, 2013 7:51 pm
Rituximab may be an effective treatment for SPMS

Last post by xpsychiatricmd « Fri Nov 08, 2013 1:57 pm
Replies: 7
by MSUK » Mon Apr 19, 2010 2:59 am

First post

Targeting B cells implicated in progressive multiple sclerosis with rituximab (Rituxan) therapy might help patients diagnosed with the disease,...

Last post

Have been recommended Rituxan for my SPMS. Looking forward being evaluated by Oncologist. Any personal experience board members want to share?

7 Replies

5452 Views

Last post by xpsychiatricmd
Fri Nov 08, 2013 1:57 pm
Rituximab Relation to ocrelizumab

Last post by centenarian100 « Wed Oct 30, 2013 10:32 am
Replies: 1
by CureOrBust » Thu Mar 28, 2013 8:40 pm

First post

It turns out that Rituximab patent expires in the US in 2015. This means that, by the time the phase III is over, the patent will be over too. So, no...

Last post

It turns out that Rituximab patent expires in the US in 2015. This means that, by the time the phase III is over, the patent will be over too. So, no...

1 Replies

5604 Views

Last post by centenarian100
Wed Oct 30, 2013 10:32 am
FDA adds boxed warning to Rituxan

Last post by NHE « Thu Sep 26, 2013 3:52 am

by NHE » Thu Sep 26, 2013 3:52 am

Boxed Warning of HBV Risk Added to Rituxan

The FDA announced today that rituximab (Rituxan) and ofatumumab (Arzerra) will now carry a boxed...

0 Replies

3486 Views

Last post by NHE
Thu Sep 26, 2013 3:52 am
Autoantigen induced clonal expansion in immortalized B cells

Last post by Anonymoose « Sat Sep 21, 2013 12:31 pm

by Anonymoose » Sat Sep 21, 2013 12:31 pm

Autoantigen induced clonal expansion in immortalized B cells from the peripheral blood of multiple sclerosis patients

We studied Ig heavy chain...

0 Replies

3240 Views

Last post by Anonymoose
Sat Sep 21, 2013 12:31 pm
Rituximab kills auto reactive plasma B cells

Last post by Anonymoose « Fri Aug 30, 2013 9:38 am

by Anonymoose » Fri Aug 30, 2013 9:38 am

I was worried about the ebv infected plasma cells escaping rituxan because plasma cells don't usually express cd20. Looks like there is a chance...

0 Replies

3200 Views

Last post by Anonymoose
Fri Aug 30, 2013 9:38 am
MS-b cell tolerance defect-rituximab efficacy

Last post by Anonymoose « Thu Aug 29, 2013 9:39 am

by Anonymoose » Thu Aug 29, 2013 9:39 am

In a study of 7 ms patients (small!), all tested positive for peripheral B cell tolerance defect. Two also tested positive for central B cell...

0 Replies

3403 Views

Last post by Anonymoose
Thu Aug 29, 2013 9:39 am
Very Successful Treatment with Rituxan

Last post by Bender « Fri Apr 26, 2013 4:15 am
Replies: 5
by Potts » Thu Feb 28, 2013 1:59 pm

First post

I was given my first treatment of Rituxan in January of 2012. Within two days of the first treatment, I had a great elimination of my symptoms....

Last post

I got chills etc... the first week or so and had my energy just flatline, but frankly I'm not sure I blame the rituxan for that. I'm at almost 3...

5 Replies

5460 Views

Last post by Bender
Fri Apr 26, 2013 4:15 am
Copaxone or Rituxan

Last post by Bender « Wed Jan 16, 2013 4:00 pm
Replies: 3
by Sqallismom » Thu Dec 09, 2010 10:16 am

First post

I have RR MS and have been using Copaxone for the last 3 years but my last MRI showed two new lesions on my spine. My Doctor has recommended Rituxan....

Last post

My doc said that she would consider Rituxan for someone JC positive because the risk is lower, but I'm surprised they put you on Tysabri first. I...

3 Replies

5821 Views

Last post by Bender
Wed Jan 16, 2013 4:00 pm
no relapse

Last post by LR1234 « Mon Feb 20, 2012 9:48 am
Replies: 1
by L » Mon Jun 07, 2010 3:12 pm

First post

We're into the second week of June. I hope that I'm safe now to post the news that this has been the first in ten years with no spring relapse (my...

Last post

Hey L,
Just seeing how you are doing. I get Spring relapses too.....every year without fail. They are getting longer and stronger though:(

1 Replies

4728 Views

Last post by LR1234
Mon Feb 20, 2012 9:48 am
first infusion

Last post by LR1234 « Mon Feb 20, 2012 9:44 am
Replies: 6
by ElMarino » Thu Oct 22, 2009 6:49 pm

First post

I had my first infusion yesterday at the Royal London hospital. I experienced no side effects whatsoever. It took nearly five hours to complete the...

Last post

Hey ElMarino,
Wondering how you are getting on.....did this drug help at all?

6 Replies

6132 Views

Last post by LR1234
Mon Feb 20, 2012 9:44 am
Third PML case reported with Rituximab

Last post by lyndacarol « Sun Jul 11, 2010 9:00 am
Replies: 1
by MSUK » Sat Jul 10, 2010 10:47 pm

First post

A case of progressive multifocal leukoencephalopathy (PML) has been reported in a rheumatoid arthritis patient taking rituximab (Rituxan) who had not...

Last post

On the This Is MS website home page there is an article, PML Seen with Rituxan for Lupus dated December 20; is there a pattern here? Tysabri...

1 Replies

5401 Views

Last post by lyndacarol
Sun Jul 11, 2010 9:00 am
Rituximab add-on therapy for breakthrough relapsing MS

Last post by MSUK « Wed Jun 16, 2010 6:49 am

by MSUK » Wed Jun 16, 2010 6:49 am

Rituximab add-on therapy for breakthrough relapsing MS: a 52-week phase II trial

Abstract

B cells and the humoral immune system have been...

0 Replies

5127 Views

Last post by MSUK
Wed Jun 16, 2010 6:49 am
Hellooooo

Last post by Algis « Thu Feb 11, 2010 7:15 pm
Replies: 1
by L » Thu Feb 11, 2010 6:13 am

First post

This section is very quiet..

Does no one take this medication?

I had an infusion in November and, according to the studies that I am familiar...

Last post

Reading... Yes, but I don't take that as it's not available here.

1 Replies

4453 Views

Last post by Algis
Thu Feb 11, 2010 7:15 pm
first infusion yesterday

Last post by ElMarino « Fri Nov 06, 2009 4:14 pm
Replies: 1
by seeker » Thu Nov 05, 2009 1:05 pm

First post

Had my first infusion of Rituxan yesterday at UCSF. Had a slight infusion reaction about two hours in that resulted in nothing more than a very itchy...

Last post

And I had my second yesterday..

I really feel that it will stop my spring relapses. I only ever get them late winter/early spring, and perhaps it's...

1 Replies

4843 Views

Last post by ElMarino
Fri Nov 06, 2009 4:14 pm
My son is in a study using Rituximab for Type1 Diabetes...

Last post by ADHDiabetic_Mom « Mon Sep 07, 2009 7:44 pm

by ADHDiabetic_Mom » Mon Sep 07, 2009 7:44 pm

I'm new on these forums, having just received a probable dx of MS (still need MRI) this week. I don't know much about Rituximab as a treatment for...

0 Replies

4713 Views

Last post by ADHDiabetic_Mom
Mon Sep 07, 2009 7:44 pm
Intravenous Steroids CAUSING bladder problems?

Last post by seeker « Sat Jul 04, 2009 10:54 am

by seeker » Sat Jul 04, 2009 10:54 am

Seems as though every time I get infused with methylprednisone (recently had 3 day course), or when I was getting cytoxan + methylprednisone, a day...

0 Replies

4767 Views

Last post by seeker
Sat Jul 04, 2009 10:54 am
Rituxan patients

Last post by Artifishual « Fri Mar 27, 2009 6:12 am

by Artifishual » Fri Mar 27, 2009 6:12 am

Are there any others out there with RRMS that have taken Rituxan? or is it just me? curious as to what others experiences have been.

Thanks in...

0 Replies

5464 Views

Last post by Artifishual
Fri Mar 27, 2009 6:12 am
new info? or not

Last post by patientx « Sat Mar 21, 2009 4:49 pm
Replies: 3
by Lars » Thu Mar 19, 2009 5:59 pm

First post

I didn't see this posted so.... here it is. Question, how does Rituximab differ from the other monoclonal antibodies such as Campath and Tysabri?...

Last post

Right. Thanks for the correction.

3 Replies

5213 Views

Last post by patientx
Sat Mar 21, 2009 4:49 pm
Rituxan Found Effective in Subset of PPMS Patients

Last post by Artifishual « Wed Mar 18, 2009 4:07 pm
Replies: 3
by marcstck » Fri Mar 13, 2009 6:21 pm

First post

Here's an abstract from a study that will be presented at the upcoming American Academy of Neurology meetings in April.

In simple terms, it found...

Last post

Yes sorry Mark that you had no results from rituxan. i saw your videos on another message board and also thought they were very cool. I have never...

3 Replies

5359 Views

Last post by Artifishual
Wed Mar 18, 2009 4:07 pm
My (unsettling) experience with Rituxan

Last post by Artifishual « Mon Feb 16, 2009 10:53 am
Replies: 1
by Elin » Fri Feb 13, 2009 3:13 pm

First post

I hope this can help others decide whether or not to try Rituxan. Perhaps I did not make the right choice.

Three weeks ago, I had my first infusion...

Last post

I received four infusions early last year and have not taken any other meds since. Before that I was taking pulse steroids. I did have a reaction...

1 Replies

6545 Views

Last post by Artifishual
Mon Feb 16, 2009 10:53 am
Increased repair?

Last post by CureOrBust « Wed Dec 10, 2008 6:09 am

by CureOrBust » Wed Dec 10, 2008 6:09 am

For both RevImmune and Campath, you read about the surprising / unexpected decreases in EDSS. Has anything similar been noted for Rituxan?

I...

0 Replies

4848 Views

Last post by CureOrBust
Wed Dec 10, 2008 6:09 am
post Rituxan blood work results

Last post by Grumpster « Mon Oct 20, 2008 11:49 am
Replies: 2
by marcstck » Thu Oct 16, 2008 10:32 pm

First post

got my blood test results back today, and Rituxan has done what it was supposed to do, my B cell counts have indeed plummeted.

Now let's see if this...

Last post

All the best to you Marc. I am rooting for you and Rituxan. A close friend works in immunology research and he could not say enough about the...

2 Replies

5813 Views

Last post by Grumpster
Mon Oct 20, 2008 11:49 am
Finally !!!

Last post by Loobie « Tue Oct 07, 2008 5:17 pm
Replies: 47
by Artifishual » Fri Oct 03, 2008 4:50 am
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First post

:D Alright!! Finally we get a place to talk about our experiences w/ Rituxan!! Thanks Thisisms !!!!

Well it has been about 7 1/2 months since my...

Last post

Thanks man.
47 Replies

21723 Views

Last post by Loobie
Tue Oct 07, 2008 5:17 pm
What is Rituxan?

Last post by Artifishual « Mon Oct 06, 2008 6:46 am
Replies: 1
by patientx » Sun Oct 05, 2008 8:00 am

First post

Can someone provide some information on Rituxan? The little I know is that it is a monclonal antibody the targets B-cells. But is it being prescribed...

Last post

hi patientx, for me it was prescribed off label, as I don't think it has been approved for ms yet!! Hopefully it will be in the near future. Rituxan...

1 Replies

6256 Views

Last post by Artifishual
Mon Oct 06, 2008 6:46 am

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