McDonald criteria

[cmcg2013]

Hello could anybody explain what an objective clinical lesion is

[jimmylegs]

short answer, not a subjective subclinical lesion. evidence picked up via a test, that doesn't rely on how you say you feel.

[cmcg2013]

Is an mri the only way to test for an objective lesion then

[centenarian100]

Jimmy Legs is correct. It is a lesion confirmed by objective evidence such as examination, visual evoked potentials, or MRI.

Lets say that you report numbness in your legs, but your examination is normal, this is subjective. However, lets say you report numbness in your legs, and you have brisk lower extremity reflexes, babinski signs (an abnormal reflex), and an enhancing lesion in your thoracic spine on an MRI, this would be objective. You don't have to have all of these some things-just some objective evidence that your symptoms were actually caused by abnormal inflammation in your nervous system. The reason for this is to prevent mis-diagnosis which is estimated to occur in 2-5% of people diagnosed with MS

-C

[cmcg2013]

Thank use have been really helpful just trying to get my head around it a bit before my neuro app because I've had a positive romberg,babinski and hoffman sign at my gp appointment I've had constant tingling in my legs for months and recently developed restless legs at night with pain and my eye goes blurry when hot and my eyelid droops ocaisionly and my balance is terrible