a fix for p.p.m.s and all m.s how to track it

[Weneedhope]

hi all how do you track this drug it's a fix for p.p.m.s dr say all kinds of m.s i hope i got that right i know i move in 8 years from now



thank you

[NHE]

Here's an article from last June which discusses Autobahn Therapeutics' ABX-003, the remyelination drug mentioned by Dennis Bourdette in the video.

Autobahn Therapeutics Opens, Aims to Treat MS by Restoring Myelin

https://multiplesclerosisnewstoday.com/ ... n-abx-002/

Note: The article discusses ABX-002, but Autobahn Therapeutics' site states that their MS candidate drug is called ABX-003.

https://autobahntx.com/our-science#our-science-module-4

Here's an overview of their pipeline.

[NHE]

Myelin repair stimulated by CNS-selective thyroid hormone action
JCI Insight. 2019 Apr 18;4(8):e126329.

Oligodendrocyte processes wrap axons to form neuroprotective myelin sheaths, and damage to myelin in disorders, such as multiple sclerosis (MS), leads to neurodegeneration and disability. There are currently no approved treatments for MS that stimulate myelin repair. During development, thyroid hormone (TH) promotes myelination through enhancing oligodendrocyte differentiation; however, TH itself is unsuitable as a remyelination therapy due to adverse systemic effects. This problem is overcome with selective TH agonists, sobetirome and a CNS-selective prodrug of sobetirome called Sob-AM2. We show here that TH and sobetirome stimulated remyelination in standard gliotoxin models of demyelination. We then utilized a genetic mouse model of demyelination and remyelination, in which we employed motor function tests, histology, and MRI to demonstrate that chronic treatment with sobetirome or Sob-AM2 leads to significant improvement in both clinical signs and remyelination. In contrast, chronic treatment with TH in this model inhibited the endogenous myelin repair and exacerbated disease. These results support the clinical investigation of selective CNS-penetrating TH agonists, but not TH, for myelin repair.

Free full text.

[Weneedhope]

i hope for all in 8 years we have a fix for this i have No one to look after me in any way

how best to get help in my stale . do you sell it all my life or wait

i track it now alot ez thank you