Mitochondrial Transplantation

[Petr75]

2022 Feb 17
Istituto per la Ricerca e l'Innovazione Biomedica, CNR, Palermo, Italy
Promising Treatment for Multiple Sclerosis: Mitochondrial Transplantation
https://pubmed.ncbi.nlm.nih.gov/35216361/

Abstract
In recent years, several studies have examined the multifaceted role of mitochondria in Multiple Sclerosis (MS), suggesting that, besides inflammation and demyelination, mitochondrial aberration is a crucial factor in mediating axonal degeneration, the latter being responsible for persistent disabilities in MS patients. Therefore, mitochondria have been recognized as a possible multiple sclerosis therapeutic target. Recently, mitochondrial transplantation has become a new term for the transfer of live mitochondria into damaged cells for the treatment of various diseases, including neurodegenerative diseases. In this hypothesis, we propose mitochondrial transplantation as a new, potentially applicable approach to counteract axonal degeneration in multiple sclerosis.

[NHE]

Promising Treatment for Multiple Sclerosis: Mitochondrial Transplantation
https://pubmed.ncbi.nlm.nih.gov/35216361/

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https://www.mdpi.com/1422-0067/23/4/2245/htm