EAE might not be the best model of MS, but better understanding of it could be a good thing:
Pubmedtinyurl
Dom.
Better knowledge of EAE
- TwistedHelix
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- TonyJegs
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EAE is a horrible model of MS. Extensive use of this model create the "autoimmunity" of MS. Now, when "immuno-modulating" drugs based on this theory failed to treat MS, what will be next?
I expect a switch to axonal dysfunction or degeneration and more genetic research. Well, another 10-15 years in a wrong direction?
Kind regards,
Tony
"When working toward the solution of a problem, it always helps if you know the answer."
-Rule of Accuracy-
EAE is a horrible model of MS. Extensive use of this model create the "autoimmunity" of MS. Now, when "immuno-modulating" drugs based on this theory failed to treat MS, what will be next?
I expect a switch to axonal dysfunction or degeneration and more genetic research. Well, another 10-15 years in a wrong direction?
Kind regards,
Tony
"When working toward the solution of a problem, it always helps if you know the answer."
-Rule of Accuracy-