Simka's latest!!

A forum to discuss Chronic Cerebrospinal Venous Insufficiency and its relationship to Multiple Sclerosis.
Post Reply
User avatar
mrhodes40
Family Elder
Posts: 2067
Joined: Thu Sep 23, 2004 2:00 pm
Location: USA
Contact:

Simka's latest!!

Post by mrhodes40 » Wed Jun 10, 2009 6:13 am


Preliminary report on pathologic flow patterns in the internal jugular and vertebral veins of patients with multiple sclerosis
Marian Simka, Jacek Kostecki, Maciej Zaniewski, Eugeniusz Majewski, Danuta Szewczyk-Urgacz
Phlebological Review 2009; 17(2):61-64
ICID: 887336
Article type: Original article
IC™ Value: 3.00

Multiple sclerosis is a chronic neurologic disease of undetermined background. Recent discoveries suggest that this disease could be a venous pathology. The study has been done to assess veins in the neck in multiple sclerosis patients, in order to confirm findings by researches from Ferrara. There were examined 8 patients with proven diagnosis of multiple sclerosis. They were performed color Doppler examination of their internal jugular veins and vertebral veins. Abnormalities were found in all patients, but no universal anatomical pattern of venous pathology existed. There were found: occlusion of one internal jugular vein - 2 patients, stenosis of one internal jugular vein - 4 patients, stenosis of both internal jugular veins - 2 patients, stiff but not yet narrowed internal jugular vein - 1 patient, reflux in internal jugular vein – 2 patients, stenosis of vertebral veins - 3 patients, reflux in vertebral veins - 1 patient. Although further studies are needed to establish the actual role for pathology of extracranial veins in the etiopathogenesis of multiple sclerosis, these investigations can open a new chapter in management of this debilitating neurologic disease.

ICID 887336

now available HERE

This is also added to the replicating studies thread...

Cheer posted an abstract of an earlier version of this paper some time ago but this is the official published version....hot off the press. The final version lost the reference to the 3 cases of probable MS who also showed this when tested and I have asked why, will post that response when we know... but it is very common for editors to as for revised papers so they may be responsible for that
marie
I'm not offering medical advice, I am just a patient too! Talk to your doctor about what is best for you...
http://www.thisisms.com/ftopic-7318-0.html This is my regimen thread
http://www.ccsvibook.com Read my book published by McFarland Health topics

LR1234
Family Elder
Posts: 1517
Joined: Wed Feb 11, 2009 3:00 pm
Location: California
Contact:

Post by LR1234 » Wed Jun 10, 2009 8:53 am

I might be because maybe the probable MSers could look like controls as they have not been totally diagnosed yet. So people might question the 100% finding. (just my thoughts)

User avatar
mrhodes40
Family Elder
Posts: 2067
Joined: Thu Sep 23, 2004 2:00 pm
Location: USA
Contact:

Post by mrhodes40 » Wed Jun 10, 2009 9:13 am

LR My thought was similar like only include them once you know the final diagnosis result so they are NOT possibly "non MSers".

Bottom line though neurological problems to the point of probable MS and then a positive doppler findings in the light of Zamboni's findings is pretty remarkable. If all were eventually dix'd with MS it is important, maybe it'll be a separate paper down the road with fllow ups...
I'm not offering medical advice, I am just a patient too! Talk to your doctor about what is best for you...
http://www.thisisms.com/ftopic-7318-0.html This is my regimen thread
http://www.ccsvibook.com Read my book published by McFarland Health topics

User avatar
wobbly
Family Member
Posts: 73
Joined: Thu Jan 01, 2009 3:00 pm

hi marie

Post by wobbly » Wed Jun 10, 2009 10:28 am

so am i one of those 8 / which 1 / i wonder / the latest is they are recruiting 1100 people some w-ms and others not 2 compare /m STAY STRONG ALL ---P S --THE JOG 4 THE JAKE which is the big fundraisor on fathers day i will sniff around [ in the post race beer tent ] all the big shots will be there :?: :?: :?:

User avatar
Loobie
Family Elder
Posts: 2197
Joined: Mon Sep 11, 2006 2:00 pm
Location: Dayton, Ohio USA
Contact:

Post by Loobie » Wed Jun 10, 2009 11:27 am

Is that Jacob's field in Cleveland?

User avatar
Sharon
Family Elder
Posts: 1282
Joined: Sun Nov 07, 2004 3:00 pm
Location: Colorado
Contact:

Post by Sharon » Wed Jun 10, 2009 12:05 pm

It would be interesting to know why they were considered probable MS'rs -i.e. lesions, neurological testing.

User avatar
wobbly
Family Member
Posts: 73
Joined: Thu Jan 01, 2009 3:00 pm

Post by wobbly » Wed Jun 10, 2009 12:18 pm

it s the jacobs neurological institute in buffalo

User avatar
mrhodes40
Family Elder
Posts: 2067
Joined: Thu Sep 23, 2004 2:00 pm
Location: USA
Contact:

Post by mrhodes40 » Wed Jun 10, 2009 12:59 pm

The answer on the three probable MSers was that the data set was too small to be useful for significance, so it was elimated.
The final version lost the reference to the 3 cases of probable MS who also showed this when tested and I have asked why, will post that response when we know
I'm not offering medical advice, I am just a patient too! Talk to your doctor about what is best for you...
http://www.thisisms.com/ftopic-7318-0.html This is my regimen thread
http://www.ccsvibook.com Read my book published by McFarland Health topics

User avatar
cheerleader
Family Elder
Posts: 5359
Joined: Mon Sep 10, 2007 2:00 pm
Location: southern California

Post by cheerleader » Wed Jun 10, 2009 1:13 pm

Thanks for posting, Marie.
I like the fact that Dr. Simka refers to it as abnormalities of the extracranial veins. This opens up the doppler scanning process of CCSVI to consider how reflux in all of the surrounding veins can signal a problem.

Dr. Simka needs to test more "probable MS" patients and controls and get a larger sample for another paper. This is a very important connection to the beginnings of MS.
Thanks for all your time and effort Dr. Simka!!!
cheer
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com

Post Reply
  • Similar Topics
    Replies
    Views
    Last post
  • Help understanding my latest blood tests
    by LisaH » Tue Mar 20, 2018 11:23 am » in Undiagnosed
    40 Replies
    4337 Views
    Last post by LisaH
    Fri May 11, 2018 8:47 pm