- Family Elder
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- Location: Paris, France
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1) I overlooked the Autonomic Nervous System which controls involuntary functions – (involuntary control of internal organs, heart rate, digestion, bladder and bowel function, respiratory rate, papillary response, vasomotor action on the blood vessels) and in particular that it leads from the spine to connect to the brain.
2) Preoccupied with the health of the inner layer of the veins – the endothelium - I overlooked the smooth muscle layer of the vascular system. Dr. Owiesy’s theory that in CCSVI MS the vein muscles may go into spasms to block off blood flow from the brain corresponds exactly to my own experience.
MY THEORY UPDATED :
Early on in the RRMS phase, the blood reflux injures the Central Nervous System (CNS) and the primary focus to stop an attack should be to restore the blood flow (CCSVI). A Shiatsu massage may suffice. Acupuncture, Osteopathic treatment, massage, TENS Acupressure, Massage. Anything to get the blood flowing unimpeded towards the heart. Dr. Owiesy’s injection of RX around the brain’s draining veins may bring blood flow relief, and of course venoplasty is designed to do just that. The major drawback to venoplasty is that stents apparently still haven’t been devised to keep the blood flowing freely and safely after venoplasty. The 2009 Stanford CCSVI venoplasty-with-stents recipients still report full recovery, but problems for some brought an end to stents for veins. Re-stenosis remains the risk to CCSVI venoplasty.
PROGRESSION : But eventually as handicap develops the body structure is compromised which puts pressure directly on the spinal cord itself or on the cerebral spinal fluid flow (CSF) with corresponding damage to the nervous system/brain. (Positive Feedback Loop)
Worse, leading from the damaged spine, impulses from the Autonomic Nervous System are disturbed resulting in dysfunction of the excretory function and eyes (for example). Venous blood flow from the brain may continue to back jet into the CNS, but the relief of venoplasty may lead only to minimal recovery of symptoms which have become more generalized through the Autonomic Nervous System and spinal cord. This may explain why up to two thirds of venoplasty recipients enjoy minor or no relief from their MS condition.
This implies as well that Progressed MS – SPMS and PPMS – is characterised by pathology in the spine which impacts the axons, walking, and the Autonomic Nervous System functions. Once MS has Progressed, opening of blood flow draining from the brain which is the goal of venoplasty may lead to a more limited relief than would have been the case had one been treated earlier.
Before Annette Funicello died April 2013 she had posted a video of herself which revealed her terribly handicapped MS body. She reported that she felt better when the blood flow was restored – her husband Glen Holt confirmed the change in her – but it was too late to heal her twisted, handicapped body. She wanted to promote the CCSVI venoplasty therapy, reporting that it was the ONLY thing which had helped her in her long losing battle with MS. Her Foundation (Annette Funicello Research Fund for Neurological Diseases) has raised money in support of CCSVI research. (It should be obvious that the pathological blood flow through her brain injured it and that my suggestion to get the blood flowing through massage, osteopathy etc would be insufficient. Once her venous brain blood flow had been restored, the damage to her nervous system had been too extensive to allow recovery.)
Joan Beal (cheerleader on http://www.thisisms.com/) writes
If there is something we can do to stop progression of MS or ease symptoms, it is important to speak out a out it. Glen says that the CCSVI venoplasty procedure performed on Annette was the first treatment b that helped her. It allowed her to swallow and breathe better. Imagine if her malf ed jugular veins could have been treated earlier. She had a 30% occlusion on one side, ormand no flow with reflux into the brain on the other. That is what CCSVI advocates and researchers are working to understand.
My husband had a reversal of gray matter atrophy after his venoplasty procedure. He also had relief in heat intolerence, fatigue and cognitive fog. This is something copaxone did not acheive for him in the two years he took it prior to his venoplasty. He remains on copaxone, the endothelial health program and keeps moving. We hope his MS will not progress. So far, so good.
That's why Annette's story, and everyone's story, is so important.
Because Annette and Glen do not want others to suffer as she has, and they are going to work for answers through her neurological foundation. http://www.annetteconnection.com/About- ... h-
https://www.facebook.com/.../ccsvi.../a ... svi.../101...(joan beal)
Back to me. My own thinking is that once MS Progression impacts the spine adversely to disturb the Autonomic Nervous System, the blood flow factor diminishes in importance in overcoming MS decline.
Previously published on my site www.mscureenigmas.net/
Best regards, Vesta