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Hey, The brain atrophy impact seems to be a very positive element and very consistent with the previous case-study where PIO was used for a person with progressive MS. Hopefully there will be continuation on this research. Best Regards, Degerlache ----------------------------------------------------...

Hey, Recalculating back the percentages, they have in this study only 2 (!!) out of 147 MS children that are not carrier of the EBV specific antigens. That is only 2 away from being able to suggest that EBV is to consider as a necessary "pre"condition (= not the same as the cause) for deve...

Hey, To go into more detail about this, the link between the previous Dr. Willems Institute (but a few years ago the name was changed to Biomed) is Dr. Zangh, currently associated with FarmaFrontiers. Dr. Zangh (co)developped the T-cell technique in the 90's at this institute before going to the Sta...

Hello, It was not mentionned specifically what type of blood analysis was done. But if you do not have the results at hand,re-check specifically level of B12 vit., as persons unable to absorb B12 via food get low level of B12 resulting in myelin destruction and neurological symptoms as well. Regards...

This seems to confirm the theories that there are 2 processes going on, on the one hand the inflammation and demyelination (T-cells) and on the other hand the axonal damage (becoming clear now that it is coming from the B-cells). In this light there is the publication of Prineas where he stated that...

Hello, If looking for a connection to insulin, there is to remind the pioglitazone (ACTOS) case story, reversing a secondary progressive case of MS and there should currently be a phase II trial on pioglitazone (but didn't hear anything about it for some time). ACTOS is a medicine (PPARgamma agonist...

Hey, So little is already knows about possible interactions and links. For instance, ACTOS (pioglitazone), used against diabetes, prevented in a case study progression of secondary progressive MS and seriously improved the situation of that person and is now evaluated in a phase II study. It would a...

Hey, There are already serious indications about involvement of EBV as - a study on nurses with blood samples dated before their start of MS showing very specific reactions agains EBV in persons later having MS, - In studies persons with MS are 100% infected with EBV, while in general it is only abo...

Thanks for this fantastic piece of information. Proving causation may not yet be possible, but using basic logical techniques some conclusions can and should already be possible I beleive, as eg. If 100% of persons with MS test positive for EBV, while only 90% of the overall population tests EBV pos...

Stick to the numbers ! There are some publications suggesting that nearly all (if not all) MS sufferers are infected by EBV while for the rest of the people the infection level is only at 95-97%. The difference of the 5 à 3% may not look so much, but if it would be confirmed on large scale studies, ...

Hey, The 15D-PGJ2 thing is not really a drug, but a prostaglandin that is created naturally within our body out of arachidonic acid which itself is coming from animal fat. (What is remarkable as many natural therapies seem to avoid animal fat) 15D-PGJ2 is a natural PPARgamma agonist. More and more r...

If EBV is actively involved in MS, it would theoretically be consistent with the potentional benfit of PPARgamma agonists. I can't find any specific studies of the effect of PPARgamma on EBV, but there seems to be general information that PPARgamma suppresses virus replication including HIV, so mayb...

After new articles on the potential benefits of PPARgamma agonists, I looked for "natural" PPARgamma agonists and found a product called "PARACTIN". They clame to be a natural PPARgamma agonist, also used for arthritis etc....

Anyone heart of PARACTIN before ?

Regards,
Degerlache

Ian, I am very interested to hear on this site about new discoveries in the EBV area. As we are talking about votes, concerning any future treatments, my vote goes out to PIOGLITAZONE (as a midlong term treatment until hopefully one day the real cause and an higly effective treatment will be found) ...

The following is pure speculation, as I am not a scientist, but as a hypothesis the benefit of statins in MS, may also go via the link of EBV.

(No need to explain I am not a strong believer of the auto-immunity strategy to combat MS)

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