Search found 4 matches

by SPMS46
Fri Nov 03, 2017 7:29 am
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: Concerns about high dose biotin and risks of infertility?
Replies: 3
Views: 11417

Re: Concerns about high dose biotin and male reproduction?

There is something else that bugged me about this study. I had to take one pill every four hours one hour before every meal or two hours after like clockwork. Visits every six weeks, MRIs every three months, an independent assessor, wearing that fitbit watch all the time, and just way too much time ...
by SPMS46
Fri Nov 03, 2017 6:21 am
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: Concerns about high dose biotin and risks of infertility?
Replies: 3
Views: 11417

Re: Concerns about high dose biotin and male reproduction?

Just to let you know, I decided not to partake in this study. It was a personal decision and to be frank, I wasn't convinced it was worth the hassle of wearing a fitbit watch all the time and doing a bunch of tests all over again and risk being on the placebo. I will monitor the results closely but ...
by SPMS46
Thu Nov 02, 2017 9:39 am
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: Concerns about high dose biotin and risks of infertility?
Replies: 3
Views: 11417

Re: Concerns about high dose biotin and male reproduction?

I received more information: The medical monitor indicated that conventional studies of genotoxicity, reproduction and development revealed no genotoxic potential of MD1003; and no toxic potential of MD1003 for reproduction and development in adult rats at doses up to 1000 mg/kg/day. Biotin administ...
by SPMS46
Thu Nov 02, 2017 7:44 am
Forum: Biotin (Qizenday, Cerenday, MD1003)
Topic: Concerns about high dose biotin and risks of infertility?
Replies: 3
Views: 11417

Concerns about high dose biotin and risks of infertility?

Hello MS community, I am a 46-year-old male with SPMS who is eligible for the MD1003 study. My main concern and my partner is on the male reproductive system after reading this study on rats, Dietary intake of high-dose biotin inhibits spermatogenesis in young rats: http://onlinelibrary.wiley.com/do...

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