Search found 21 matches

by Kheuer
Wed Jan 09, 2019 9:11 am
Forum: MS Etiology and Pathogenesis
Topic: Myelocortical MS (MCMS)
Replies: 6
Views: 1170

Re: Thanks to MS-UK: New type of MS discovered

These are big news. First of all, because 12% of patients have damage in the WM without demyelination. So much for the autoimmune demyelination theories. Your statement is not scientifically supportable. This subset of patients may be able to re-myelinate white matter more efficiently. And AI demye...
by Kheuer
Wed Jan 09, 2019 8:57 am
Forum: General Discussion
Topic: New lesion despite being PPMS or SPMS
Replies: 14
Views: 1174

Re: New lesion despite being PPMS or SPMS

Try nicotinic acid, the B3 that makes you flush.

Most people it only takes 50mg, for me it takes 1000. Klenner said 750 was usually necessary for MS persons to flush back in the 70s.

It's completely safe, in fact it is the single most effective cholesterol medication ever.
by Kheuer
Wed Jan 09, 2019 8:50 am
Forum: MS Etiology and Pathogenesis
Topic: Wolfson Institute of Preventive Medicine. EBV is MS cause.
Replies: 1
Views: 594

Re: Wolfson Institute of Preventive Medicine. EBV is MS cause.

EBV and the Human Herpes Virus family activate the epigenetic pathway for the MS genetically prone. The EBV does not cause MS. An inflammatory cascade initiated by CD20+ B cells that recruits T cells to attack myelin, and creates multiple inflammatory cytokine and protein cascades that prevent corre...
by Kheuer
Wed Jan 09, 2019 8:44 am
Forum: Ocrevus (Ocrelizumab)
Topic: Ocrevus is a Wonder Drug for MS
Replies: 9
Views: 3367

Re: Ocrevus is a Wonder Drug for MS

"It is the ONLY THERAPY to ever do #5 and #6" Not true - there are now other safe therapies doing #5 and #6. Which clinically documented? Because you're statement is factually incorrect. Ocrevus is the ONLY treatment to stop progression and also recover LOST function, unless you are talking the Kle...
by Kheuer
Wed Jan 09, 2019 8:33 am
Forum: Regimens
Topic: to add to jimmyleg's info/thiamine B1
Replies: 23
Views: 7989

Re: to add to jimmyleg's info/thiamine B1

NAD+ reverses animal models of autoimmune diseases


https://www.prohealth.com/library/can-a ... very-86540
by Kheuer
Wed Jan 09, 2019 8:29 am
Forum: Regimens
Topic: to add to jimmyleg's info/thiamine B1
Replies: 23
Views: 7989

Re:

Jimmy...What form of B1 are you taking? Oral? I'm taking benfotiamine at present and starting im injections today when it arrives. Yes klenner's info is dated but if one looks for the logic it's there I believe(albeit simplistic) I don't think they expected any "layman reasearch" in those days(pre-...
by Kheuer
Wed Nov 21, 2018 5:44 pm
Forum: Regimens
Topic: Ocrevus
Replies: 4
Views: 2010

Re: Ocrevus

Hi there. My husband was diagnosed with RRMS back in May, but now the doctor thinks he may have PPMS. He suggested that we look into Ocrevus. I have been reading about it a little and it sounds scary (could cause cancer, could lead to death), but it's the only MS drug out there that treats PPMS. An...
by Kheuer
Wed Nov 21, 2018 5:35 pm
Forum: Drug Pipeline
Topic: The Misfortune of MS Drugs
Replies: 6
Views: 1860

Re: The Misfortune of MS Drugs

Nicotinic acid in high doses
by Kheuer
Wed Nov 21, 2018 5:31 pm
Forum: Ocrevus (Ocrelizumab)
Topic: Ocrevus is a Wonder Drug for MS
Replies: 9
Views: 3367

Re: Ocrevus is a Wonder Drug for MS

but is it any better then rituximab? My doc wants me to go on rituximab and keep taking avonex as the insurance company wuill keep paying for both. Short answer = yes Long answer = 1. It is 100% human versus the human/mouse chimeric rituxan 2. It has a higher binding affinity for CD20 expressing b ...
by Kheuer
Wed Oct 31, 2018 4:54 am
Forum: General Discussion
Topic: Fed up PRMS looking for anything !!
Replies: 14
Views: 1006

Re: Fed up PRMS looking for anything !!

My own experience with only 1000 mg of nicotine acid because that's actually how much it takes me to flush now is that it completely removed my need to take Skelaxin for the pain and has also increased my stamina such that prior to diagnosis I could barely get out of my car and now I can mow my 2/3 ...
by Kheuer
Wed Oct 31, 2018 4:51 am
Forum: General Discussion
Topic: Fed up PRMS looking for anything !!
Replies: 14
Views: 1006

Re: Fed up PRMS looking for anything !!

All the clinical data shows that ocrevus takes 2 years to show any efficacy at stopping progression of the disease give it some time. Emerging data from some of the longer Trials of ocrevus have shown that it has actually helped some patients regain lost cognitive and physical function You could als...
by Kheuer
Wed Oct 31, 2018 4:48 am
Forum: General Discussion
Topic: Link Between Gut Flora and Multiple Sclerosis Discovered
Replies: 19
Views: 1532

Re: Link Between Gut Flora and Multiple Sclerosis Discovered

Of note memory B cells are actually implicated in Guillain-Barre syndrome which is another demyelinating disease

https://www.ncbi.nlm.nih.gov/m/pubmed/28284328/

Memory B cells in Guillain-Barré syndrome.
by Kheuer
Wed Oct 31, 2018 4:45 am
Forum: General Discussion
Topic: Link Between Gut Flora and Multiple Sclerosis Discovered
Replies: 19
Views: 1532

Re: Link Between Gut Flora and Multiple Sclerosis Discovered

It actually makes sense that in Ms part of the pathology is that B cells activate T-cells to become pathogenic because in some types of immunizations like tetanus for example the B cells Ferry the toxoid to the T cell to train the T-cell to recognize the toxoid as something to create an antigen agai...
by Kheuer
Wed Oct 31, 2018 4:42 am
Forum: General Discussion
Topic: Link Between Gut Flora and Multiple Sclerosis Discovered
Replies: 19
Views: 1532

Re: Link Between Gut Flora and Multiple Sclerosis Discovered

Actually, it is CD20 b cells that cause an inflammatory cascade initially, resulting in demyelination and abnormal re-myelination. New evidence has identified that B cells in persons with MS activate T-cells to become pathogenic so the result is many T cells are found in some of the larger lesions a...
by Kheuer
Wed Oct 31, 2018 4:33 am
Forum: Ocrevus (Ocrelizumab)
Topic: Second Infusion two weeks away, I feel like death? Any other
Replies: 11
Views: 1857

Re: Second Infusion two weeks away, I feel like death? Any o

@ anonymouse

Ocrevus has been clinically shown to stop progression, and in emerging data, after 4+ years it has been shown to actually help some patients recover LOST function, physical and cognitive.

Google it