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These are big news. First of all, because 12% of patients have damage in the WM without demyelination. So much for the autoimmune demyelination theories. Your statement is not scientifically supportable. This subset of patients may be able to re-myelinate white matter more efficiently. And AI demye...

Try nicotinic acid, the B3 that makes you flush.

Most people it only takes 50mg, for me it takes 1000. Klenner said 750 was usually necessary for MS persons to flush back in the 70s.

It's completely safe, in fact it is the single most effective cholesterol medication ever.

EBV and the Human Herpes Virus family activate the epigenetic pathway for the MS genetically prone. The EBV does not cause MS. An inflammatory cascade initiated by CD20+ B cells that recruits T cells to attack myelin, and creates multiple inflammatory cytokine and protein cascades that prevent corre...

"It is the ONLY THERAPY to ever do #5 and #6" Not true - there are now other safe therapies doing #5 and #6. Which clinically documented? Because you're statement is factually incorrect. Ocrevus is the ONLY treatment to stop progression and also recover LOST function, unless you are talking the Kle...

NAD+ reverses animal models of autoimmune diseases


https://www.prohealth.com/library/can-a ... very-86540

Jimmy...What form of B1 are you taking? Oral? I'm taking benfotiamine at present and starting im injections today when it arrives. Yes klenner's info is dated but if one looks for the logic it's there I believe(albeit simplistic) I don't think they expected any "layman reasearch" in those days(pre-...

Hi there. My husband was diagnosed with RRMS back in May, but now the doctor thinks he may have PPMS. He suggested that we look into Ocrevus. I have been reading about it a little and it sounds scary (could cause cancer, could lead to death), but it's the only MS drug out there that treats PPMS. An...

Nicotinic acid in high doses

but is it any better then rituximab? My doc wants me to go on rituximab and keep taking avonex as the insurance company wuill keep paying for both. Short answer = yes Long answer = 1. It is 100% human versus the human/mouse chimeric rituxan 2. It has a higher binding affinity for CD20 expressing b ...

My own experience with only 1000 mg of nicotine acid because that's actually how much it takes me to flush now is that it completely removed my need to take Skelaxin for the pain and has also increased my stamina such that prior to diagnosis I could barely get out of my car and now I can mow my 2/3 ...

All the clinical data shows that ocrevus takes 2 years to show any efficacy at stopping progression of the disease give it some time. Emerging data from some of the longer Trials of ocrevus have shown that it has actually helped some patients regain lost cognitive and physical function You could als...

Of note memory B cells are actually implicated in Guillain-Barre syndrome which is another demyelinating disease

https://www.ncbi.nlm.nih.gov/m/pubmed/28284328/

Memory B cells in Guillain-Barré syndrome.

It actually makes sense that in Ms part of the pathology is that B cells activate T-cells to become pathogenic because in some types of immunizations like tetanus for example the B cells Ferry the toxoid to the T cell to train the T-cell to recognize the toxoid as something to create an antigen agai...

Actually, it is CD20 b cells that cause an inflammatory cascade initially, resulting in demyelination and abnormal re-myelination. New evidence has identified that B cells in persons with MS activate T-cells to become pathogenic so the result is many T cells are found in some of the larger lesions a...

@ anonymouse

Ocrevus has been clinically shown to stop progression, and in emerging data, after 4+ years it has been shown to actually help some patients recover LOST function, physical and cognitive.

Google it