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by jimmylegs
Mon Jan 30, 2023 9:25 am
Forum: Natural Approach
Topic: cannabinol promotes functional remyelination
Replies: 0
Views: 2

cannabinol promotes functional remyelination

i had no idea. met a dude who was working at the grocery store, he had a lot to say about cbd oil so i said i would go home and look up what it might be able to accomplish for remyelination. i hadn't been paying attention. first find for / new to me: Δ9-Tetrahydrocannabinol promotes functional remye...
by jimmylegs
Sun Jan 29, 2023 6:56 pm
Forum: Natural Approach
Topic: MS: most important hormones
Replies: 0
Views: 19

MS: most important hormones

last couple years' rabbit hole for sure! Influence of hormones in multiple sclerosis: focus on the most important hormones (2023) https://link.springer.com/article/10.1007/s11011-022-01138-7 "Hormonal imbalance may be an important factor in the severity of multiple sclerosis (MS) disease. In th...
by jimmylegs
Tue Jan 24, 2023 6:45 am
Forum: Undiagnosed
Topic: Twitching and now upper leg Muscle spasms in morning
Replies: 4
Views: 86

Re: Twitching and now upper leg Muscle spasms in morning

hi - recopying from / adding to yesterday's post in a diff thread: "it's weird - just this year something like this issue has started to creep up on me. i... not every day, is more like an involuntary 'cat-stretch' routine with my calves, and only first thing in the morning. on bad days, i noti...
by jimmylegs
Mon Jan 23, 2023 3:01 pm
Forum: Undiagnosed
Topic: Spasticity when awakening - Feet Forced Outwards
Replies: 5
Views: 281

Re: Spasticity when awakening - Feet Forced Outwards

it's weird - just this year something like this issue has started to creep up on me. it doesn't affect the direction of my feet at all. it's not every day, is more like an involuntary 'cat-stretch' routine with my calves, and only first thing in the morning. on bad days, i notice a definite postural...
by jimmylegs
Mon Jan 16, 2023 7:46 am
Forum: Natural Approach
Topic: all things vitamin D
Replies: 1085
Views: 199698

Re: all things vitamin D

very nice to see :)

Zinc and its role in vitamin D function (2022)
https://www.sciencedirect.com/science/a ... 4122000190

recalling this frustrating 2014 thread
viewtopic.php?p=223430#p223430
by jimmylegs
Sat Jan 14, 2023 10:31 am
Forum: Undiagnosed
Topic: Is this MS Hug and other questions
Replies: 9
Views: 246

Re: Is this MS Hug and other questions

ah ok, sw US makes some sense of 42.9 ng/ml without supplementation. i'm at 43 deg latitude, so it's more challenging to get to healthy d3 levels, esp since we also tend to go with the climate control option. i've definitely been tweaking my supplemental d3 intake over the past year. my last three D...
by jimmylegs
Thu Jan 12, 2023 3:14 pm
Forum: Undiagnosed
Topic: Is this MS Hug and other questions
Replies: 9
Views: 246

Re: Is this MS Hug and other questions

ok now will go through looking for anything potentially modifiable linked to your reported challenges. i don't know much about the background conditions you list, but also enjoy a fun little cluster of autoimmune diagnoses. re uveitis. which (if any) of these risk factors might be contributing in yo...
by jimmylegs
Thu Jan 12, 2023 12:56 pm
Forum: Undiagnosed
Topic: Is this MS Hug and other questions
Replies: 9
Views: 246

Re: Is this MS Hug and other questions

hi again, i'm sure we are pleased to provide some input in hopes that it might prove helpful. it may be reassuring to know that magnesium is absolutely a mineral to keep top of mind with or without an msdx. re b12, i used to be deficient from long term severely restrictive diet. many years later, i ...
by jimmylegs
Thu Jan 12, 2023 6:52 am
Forum: Undiagnosed
Topic: Is this MS Hug and other questions
Replies: 9
Views: 246

Re: Is this MS Hug and other questions

hi and welcome mnh! i am going into a meeting but briefly, i hope you can elaborate on your d3 regimen, and any other supplements in your routine. as one potential piece of low hanging fruit from your situation, i am curious about any other details of total daily magnesium intake from all sources, n...
by jimmylegs
Wed Jan 11, 2023 12:36 pm
Forum: Regimens
Topic: Hormone Replacement
Replies: 69
Views: 6794

Re: Hormone Replacement

so the latest is that the specialist is not bothered about my below 'normal' TSH. sticking to the established routine works for me :) here's hoping the juggling effort with the extra iron has a measurable effect soon - or at least noticeable, for both of us!
by jimmylegs
Mon Jan 09, 2023 5:41 am
Forum: Regimens
Topic: Hormone Replacement
Replies: 69
Views: 6794

Re: Hormone Replacement

ack it's always something, right? it sounds like iron is the more reasonable explanation for fatigue than a tendency to subclinical hypothyroidksm. my ferritin has been on a downward trend too. am well below target level. meanwhile, a couple of years ago, too high. not sure which factors were contri...
by jimmylegs
Thu Jan 05, 2023 6:03 am
Forum: Undiagnosed
Topic: Temporary hand paralysis years ago. MS?
Replies: 4
Views: 117

Re: Temporary hand paralysis years ago. MS?

hi and welcome nikki. i can definitely empathize at least a little bit, in part based on being female and having been diagnosed in my 30s. best of luck with your next steps, and we'll definitely be here to help out in whatever ways we can!
by jimmylegs
Tue Jan 03, 2023 4:34 pm
Forum: Regimens
Topic: Hormone Replacement
Replies: 69
Views: 6794

Re: Hormone Replacement

welp, this morning's results are starting to come in and TSH flagged low. looks like i'll have a few other things to adjust as well!
by jimmylegs
Sun Jan 01, 2023 5:23 pm
Forum: Regimens
Topic: Hormone Replacement
Replies: 69
Views: 6794

Re: Hormone Replacement

ok thx :) on the surface, that sounds like my overnight pattern if not actually sleeping. i will take a look!
by jimmylegs
Sat Dec 31, 2022 10:16 am
Forum: Regimens
Topic: Hormone Replacement
Replies: 69
Views: 6794

Re: Hormone Replacement

oh interesting. here, the local lab's range for TSH looks more narrow (0.32-4.00 mIU/L), and for T4 it looks lower (9-19 pmol/L). either way, from here it does look like your TSH is on the high side. that said, these look interesting: ...estimated normal, low, and high ranges of TSH levels for adult...

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