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Thanks Bob!

Does anyone know if Biogen has ever published the results of the phase II trial of Rituxan in PPMS? I wonder, because I simply don't find anything about it. Or did they start right away with Phase III . I did not think this is possible...

nati

No risk, no fun!

My point is that the people at Johns Hopkins aren't saying that Revimmune won't stop the disease process in PPMS (or SPMS) because I think it's already proven that it will work stop the disease progression. ... I don't like Accentia announcing a primary endpoint with Revimmune as a decrease in symp...

Here is some research that I have found about cyclophosphamide. Not HiCy though . Seems that cyclophosphamide can have a positive effect even in PPMS when used early. I admit, that the results are not spectacular because the first article only checked efficiency for 12months and the second article s...

Dear Marcstck Well, that's not good news. Like you I had no OB at my first LP last year and my MRI showed very few t2 spots with no inflammation. As far as I know, in PPMS the scientists think that it's more antibodies produced by B-cells that cause the problem, not T-cells. I have high hopes in Rit...

Robbie Yes, lots of us will stand in the storm and watch others to go on with their lifes with little or no disability. But it has always been that way. And what is even worse: there are parts in this world where people die because of stupid little infections, knowing, that there exists a simple rem...

Bob, you are as always thorough and solid in your answers. :) I am just so impatient which is not good for a patient 8) There is really lots of stuff going on in research and I cannot wait Campath, FTY720, HiCy, Tovaxin to become regular treatments. Well, even if I might not be able to profit from t...

Yes, there is hope! A lot of hope
If your neuro is up to date, he will know about Campath. Look at the Campath section here.
My new neuro is fan of this treatment and very keen to see it on the market as soon as possible.
Btw, I am glad for you that Copaxone is working.

Best
Nati

Redsonja, I see that you are from Germany. Well, I am from Switzerland and please don't get me wrong when I say the following things: I used to read in German and Swiss MS-forums and usually felt depressed and hopeless. I dislike the fatalistic attitude of the people there, that nothing can be done ...

Hi It's me again! It's seems that with all therapies coming up now, the fact seems to be: the earlier the treatment, the better the outcome. On the other hand lots of doctors hesitate to go for the heavier stuff when MS is early and "mild" or want first to try some established therapies. O...

Chris I do none of this "diets". But since there is some evidence that vit.3 could help to prevent MS or lower the risk (don't think it helps, if you already have MS) and some smaller studies have shown some results with a low-fat diet to prevent relapses in less severe MS a little... I th...

Bob I am no scientist and only understand a tiny part about how the upcoming new therapies work and even this little part is more vague than anything else (hey, I do my PhD in history of art :wink: ). I also don't see any real MS cure for the next 20 years. And with cure I mean the complete recovery...

Hi Robbie Are you cynical now? If not: Please don't get me wrong, the 65% has nothing to do with the HiCy! It's pure imagination what the Olympus results with Rituxan for PPMS might bring and drive me into dispair... "thinking by myself": Perhaps I should delete that phrase... :roll:

Damn, I really don't remember where I have read that article but I was very disappointed. About the misconception you might be right. But then, it's hope that leeds this people! We do arrange our lives around this shit and go on as good as possible, but what wouldn't we give to get our old self back...