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CureorBust wrote: Racemic means its actually contains both the R and L forms in equal proportions, not purely R . Thanks for correcting me, I automatically assumed "racemic" would translate to the R form....Ooops big time. CureorBust Wrote : Whereas I think R-ALA is an antioxidant and works by repa...

In this study (full text open access) the researchers performed prior to the clinical trial: Pharmokinetic study of lipoic acid in multiple sclerosis they used the "r" form of lipoic acid. Lipoic acid in human studies Viatris® (now called Meda Pharma®) provided a tablet formulation containing 600 mg...

Thank you Brett and thanks also to Dr. Kalincik for addressing my questions. I've read the transcript and as I understand it this study indicates higher efficacy treatments and fewer relapses (ARR) would potentially give someone with an EDSS = or > 3 a 10% or 1 in 10 chance of a lower likelihood of ...

Thank you for this opportunity. In general, for all outcome data in clinical trials I would be interested in knowing the absolute risk reduction outcomes and not just the relative risk reduction outcomes. I believe this statement from the immunotherapy in advanced MS abstract: "increased utilisation...

Hi Trying to be Strong and welcome I must say 65 isn't all that bad. :-D Medicare contains 4 basic parts, Part A, Part B, Part C, and Part D...Part D is a plan that covers prescription drugs and you usually have quite a choice of Part D providers. A key to having coverage for MS drugs is to choose a...

Hi PN I can report that I am still taking progesterone (going on 10+ years I think) and am still doing well re: MS. Guesstimate that EDSS still less than 1 (it's never been formally administered). I hope others report in. Given the Vitamin D you're doing, you may be interested in this article (open ...

The Washington Post had a "Wonkblog" today entitled: You can now track the billions that drug companies pay doctors and hospitals ..the federal government has compiled a massive database of how much drug and device companies spend on consulting fees, research grants, travel, free lunches and other i...

I know there are a lot of inquiring minds here at TIMS and I learned from the MS Discovery Forum that the journal Multiple Sclerosis (and other neuro journals) are open access (only through the end of September). You do have to register . When I registered I found I had to indicate an “area of inter...

Hi Thekla I don't take a break from progesterone during the month....I was diagnosed post menopause (at 57) so I didn't concern myself with natural fluctuations--but I have also read about taking a week off and have always assumed that applies to people pre menopause. Maybe I should do some more rea...

Erika....how are you doing? Hopefully better. Since it seems to germane to the thread topic, I also want to add this quote (from the NMSS report on the AAN meeting earlier this year) Progression and menopause: Dr. Riley Bove, who is funded by an American Brain Foundation-National MS Society Clinicia...

Great question Thekla I wouldn’t take them together. I try to take my estriol and progesterone at least 4 hours apart. I use progesterone cream in the morning and late evening. My 8 mg estriol is compounded with 100 mg. progesterone which I take late afternoon but obviously “together”. LOL The reaso...

Hi all...just wanted to let you know the entire paper is available and may (or, may not) offer some clarification.

Transvascular Autonomic Modulation: A Modified Balloon Angioplasty Technique for the Treatment of Autonomic Dysfunction in Multiple Sclerosis Patients

Take care all

Sharon

Hi Kronk Did someone have there beaker upside down?!? In all likelihood they did. Testing hormone levels is not as straightforward as one might think so without knowing exactly how they measured the levels and did the testing, it's hard to tell what's happening. Here's a link from the Mayo Clinic Cl...

Hi Squeakycat Thanks for your comments...but one quick clarification, this was about "estriol", a different form of estrogen than estradiol (which is what you referenced). The first comment is simply that I suspect that the benefits of estradiol are completely independent of Copaxone I am in total a...

Thanks for that clarification Kronk. I was about to go ballistic if they'd measured estriol in men but not women....and I'm still not real happy that the recent info on testosterone didn't include women as there is a history of low testosterone impacting women as you and Leonard have both pointed ou...