Search found 9 matches

by swynjones
Tue Sep 14, 2010 1:54 pm
Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
Topic: Shoes, CCSVI and MS
Replies: 12
Views: 3412

1eye. many thanks. that's really very interesting. exactly the sort of thing that I was interested to know. As I said my wife and I were totally and utterly convinced at the time that the culprit was these shoes and that it was a postural thing. And then of course we were made to feel stupid by a ne...
by swynjones
Tue Sep 14, 2010 12:24 pm
Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
Topic: Shoes, CCSVI and MS
Replies: 12
Views: 3412

Shoes, CCSVI and MS

Hi everyone Reading up about CCSVI started me re-thinking about the time of my wife's very first MS attack. And about how sometimes we dont always share information about things because they seem silly or they dont seem to fit at the time with accepted wisdom of what MS is or what neurologists tell ...
by swynjones
Thu Jul 15, 2010 2:09 am
Forum: General Discussion
Topic: CRABs dont slow EDSS progression - 3 studies
Replies: 23
Views: 6669

Yes I do work in the drug industry. But the company I work for is not active in MS research. I work in the cancer research area and I know how hard everyone arounds me works to find that drug target that is going to make a different to patients and improve cancer survival rates. I am 100% certain t...
by swynjones
Wed Jul 14, 2010 7:55 am
Forum: General Discussion
Topic: CRABs dont slow EDSS progression - 3 studies
Replies: 23
Views: 6669

My issue with Embry's article is that at the end of the day here he is being critical of the MS drugs. But there is zero scientifically proven evidence that his BBD has any effect on 1.disease progression or 2.relapse rate. This seems like a perfect example of an Ad Hominem Tu Quoque fallacy. "...
by swynjones
Wed Jul 14, 2010 4:52 am
Forum: General Discussion
Topic: CRABs dont slow EDSS progression - 3 studies
Replies: 23
Views: 6669

Your point about the difference between controlled clinical trials and retrospective analysis is basically valid. But I think there is no better data out there. The CRABs where approved by primary endpoints of MRI lesions and relapse rate which is not a valid indicator for EDSS progression over tim...
by swynjones
Wed Jul 14, 2010 4:47 am
Forum: General Discussion
Topic: CRABs dont slow EDSS progression - 3 studies
Replies: 23
Views: 6669

from which I would imagine he himself has made money through his book sales. Dr.Embry is backing CCSVI and has has made donations for CCSVI study, which if turns out be effective can put him out of business. That speaks volumes about his money making agenda. Have to say it is rather annoying the an...
by swynjones
Tue Jul 13, 2010 10:17 pm
Forum: General Discussion
Topic: CRABs dont slow EDSS progression - 3 studies
Replies: 23
Views: 6669

@swynjones: While the article does suggest to promote CCSVI I think the major point - and the point that I wanted to bring up here - is that the CRABs do not improve EDSS progression. Accepting that conclusion its imo. highly questionable whether its justified to spend that amount of money (like 15...
by swynjones
Tue Jul 13, 2010 11:18 am
Forum: General Discussion
Topic: CRABs dont slow EDSS progression - 3 studies
Replies: 23
Views: 6669

Embry makes some valid points here regarding the need for an open and thorough look at CCSVI. But ultimately this article is a little bit hypocritical because he criticises the CRABS due to 3 studies which have not demonstrated clear efficacy in reducing disease progression. But importantly the CRAB...
by swynjones
Mon Jun 07, 2010 4:14 am
Forum: General Discussion
Topic: Multiple sclerosis risk sharing scheme: a costly failure
Replies: 32
Views: 9298

A copy of a letter I have sent to the editor of the Independent. Dear Sirs I wish to take issue with the article “MS drug trial 'a fiasco' – and NHS paid for it” that appeared in the Independent on the 4th June 2010 written by your Health Editor Jeremy Laurance (< shortened url >). The article was i...

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