Search found 1612 matches

by dignan
Sun Aug 26, 2012 10:57 am
Forum: Drug Pipeline
Topic: Summary of the pipeline
Replies: 432
Views: 168763

Re: Summary of the pipeline

Thanks Cure. I had seen something about it last week, but could not find any confirmation. I just looked again and there was a press release on August 21: http://tinyurl.com/8gfzkee I am glad this Kv1.3 channel blocker has finally made it to the clinic after years of press releases and interesting a...
by dignan
Fri Jun 08, 2012 7:40 am
Forum: General Discussion
Topic: How likely will there be a cure for MS within the next 10 yr
Replies: 47
Views: 18082

Re: How likely will there be a cure for MS within the next 1

If by "cure", you mean something available to people with MS and not just a lab discovery, I'd say it's highly unlikely that there will be a cure in the next 10 years. It often takes around 10 years for substances to go through the 3 phase clinical trial process and gain regulatory approval, and at ...
by dignan
Thu Jun 07, 2012 6:59 am
Forum: Aubagio (teriflunomide)
Topic: Aubagio MS drug by Sanofi
Replies: 3
Views: 8301

Re: Aubagio MS drug by Sanofi

Until recently, it was called teriflunomide. I guess as it got close to approval, the marketing folks got their hooks into it and came up with Aubagio.
by dignan
Sat Mar 31, 2012 10:31 am
Forum: General Discussion
Topic: Breakthrough in nerve mapping gives hope for neurologists
Replies: 1
Views: 1067

Re: Breakthrough in nerve mapping gives hope for neurologist

This research is part of the Human Connectome project (http://www.thisisms.com/forum/post136622.html). It is nice to see that they are starting to make real progress.

http://www.siliconrepublic.com/innovati ... -3d-nerve/
by dignan
Tue Jan 10, 2012 12:54 pm
Forum: General Discussion
Topic: Prolactin secretion stimulates oligodendrocyte
Replies: 3
Views: 1210

Re: Prolactin secretion stimulates oligodendrocyte

It has been in the pipeline for a while now. I hope they are on to something. Here are some other links that you might have seen already: http://www.stemcellthera.com/Technology.aspx?section=488 http://cnrp.marketwire.com/cnrp_files/20090409-409SSS1.pdf http://cnrp.marketwire.com/cnrp_files/20080707...
by dignan
Fri Oct 14, 2011 12:35 pm
Forum: General Discussion
Topic: Epigenetics
Replies: 21
Views: 6676

Re: Epigenetics

More interesting stuff on twins and epigenetics: There is no such thing as identical where twins are concerned October 14, 2011 - Identical twins have identical genomes, but that is where it stops. There are subtle differences in their personalities, how they look, how they act and in their suscepti...
by dignan
Thu Oct 13, 2011 12:01 pm
Forum: Stem Cells
Topic: New method isolates best brain stem cells to treat MS
Replies: 1
Views: 1153

Re: New method isolates best brain stem cells to treat MS

I think this is big news, thanks squiffy.
by dignan
Tue Oct 04, 2011 7:03 pm
Forum: General Discussion
Topic: Could this be the beginning of the end to RRMS?
Replies: 8
Views: 1765

Re: Could this be the beginning of the end to RRMS?

rssugg, I would love it if Revimmune was on the cusp of FDA approval, but unfortunately, Accentia hasn't even started the pivotal phase 3 trial(s) yet. It will probably take 1-2 years to recruit all the study participants, then another 2 years to run the trial(s), a few months for data compilation a...
by dignan
Tue Aug 23, 2011 7:21 am
Forum: Daily Life
Topic: i am sad
Replies: 2
Views: 1662

Yes, sad.
by dignan
Mon May 30, 2011 7:08 pm
Forum: Mavenclad (Cladribine)
Topic: Cladrabine - Movectro
Replies: 64
Views: 11039

That is handy info Bromley, thanks. I hadn't twigged that BG12 was that good compared with gilenya.
by dignan
Thu May 12, 2011 1:14 pm
Forum: General Discussion
Topic: Sex hormone precursor inhibits brain inflammation
Replies: 0
Views: 1514

Sex hormone precursor inhibits brain inflammation

An interesting finding with MS implications. Sex hormone precursor inhibits brain inflammation May 12, 2011 -- Researchers at the University of California, San Diego School of Medicine have discovered a steroid hormone that inhibits inflammation in the brain. The findings, to be published in the May...
by dignan
Sat May 07, 2011 12:12 pm
Forum: General Discussion
Topic: New theory of MS
Replies: 11
Views: 3089

More on MS as an example of neurocristopathy: Paradigms in multiple sclerosis: time for a change, time for a unifying concept. Inflammopharmacology. 2011 May 6. [Epub ahead of print] Krone B, Grange JM. Institute of Virology, Centre for Hygiene and Human Genetics, University of Göttingen, Kreuzbergr...