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Aretha Franklin, the Queen of Soul, died Thursday morning at her home in Detroit after a long battle with cancer, her family said in a statement. She...

Fish: Friend or Foe?

Fears of contaminants make many unnecessarily shy away from fish.

Excerpt

... Striking a Balance
Avoiding fish is...

5 of the best exercises you can ever do

If you're not an athlete or serious exerciser — and you just want to work out for your health or to fit...

Note: This info was posted to another forum, but it seemed like it might be of benefit here as well.

Motorized pedal and movement devices which...

Top-down proteomic profiling of human saliva in multiple sclerosis patients.

Abstract

Multiple sclerosis is a chronic disease of the central...

Editorial of the Multiple Sclerosis Journal

Are neurofilaments valuable biomarkers for long-term disease prognostication in MS?

Neuroaxonal...

DNA methylation signatures of a large cohort monozygotic twins clinically discordant for multiple sclerosis

Abstract

Multiple sclerosis (MS) is...

This could save some people with mild MS from being treated

Neurofilaments and 10-year follow-up in multiple sclerosis

Background:

The role...

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Five-Year Longitudinal Study of Neck Vessel Cross-Sectional Area in Multiple Sclerosis

BACKGROUND AND PURPOSE: Alterations of neck vessel...

It seems that microglia activation could be a symptom of axonal damage, and not the ultimate cause nor related to pre-active lesions. Microglia...

It seems so.

Microglia P2X4 receptors as pharmacological targets for demyelinating diseases

Multiple sclerosis (MS) is a chronic inflammatory...

Extracranial Veins in Multiple Sclerosis: Is There a Role for Vascular Surgery?

Conclusions and Perspectives

From a pathophysiological point...

MS patients present oligoclonal bands (OCB) in their cerebrospinal fluid (CSF). Among the oligoclonal bands there could be some related to...

MS patients present oligoclonal bands (OCB) in their cerebrospinal fluid (CSF). Among the oligoclonal bands there could be some related to...

Cardiovascular conditions are as common in those with demyelinating diseases (multiple sclerosis, neuromyelitis optica and transverse myelitis)...

In case you have non-standard MS or non-responsive to medication this could be interesting.

Mayo Clinic develops neuro test that distinguishes...

Drugs evaluated in these studies include specific therapeutics which have already granted FDA licensure like interferon beta, glatiramer acetate, and...

PET (Positron imaging technology) is a imaging method able to show the molecular structure of a lesion.

Several radioligands, compounds that work as...

Multiple sclerosis with and without CSF bands: Clinically indistinguishable but immunogenetically distinct

Abstract

We sought to determine...

It seems that a biomarker in blood predicts response to GA

Phosphorylated SIRT1 as a biomarker of relapse and response to treatment with...

Here there is a freely available review about the state-of-the-art as it was 2 years ago.

Personalised medicine for multiple sclerosis care...

I went and got my lumbar puncture Tuesday afternoon, and it went pretty well. I only felt the initial needle prick and after that it was completely...

iConquerMS™ Initiative Launches Personalized Medicine Research in Multiple Sclerosis

REAL MS™ Will Explore Causes and Factors that Affect...

Personalised medicine tries to select the best medicine available for each patient based in biomarkers. Now this is starting to be possible in MS....

Personalized medicine here means to divide the patients in subgroups so that the response to medication is optimal.

It seems that some hospitals...

Pathology and Pathogenesis of Progressive Multiple Sclerosis: Concepts and Controversies

Summary

Multiple sclerosis changes not only its...

In a small study patients were clustered into 6 distinct subsets by baseline cytokine profiles of CSF.

Two subsets were associated with patients...

EBV in Brain

Source:

The best evidence to date does suggest that EBV is present in both MS and control brains, but is more common in pwMS (90% vs...

It seems that B-cells are responsible for producing the oligoclonal Bands (OCB) that appear in MS. For some reason which I don't understand, the...

FDA approves cannabidiol Epidiolex

The Food and Drug Administration recently approved the first drug made from Cannabis sativa. This plant is...

In the Pipeline-Multiple Sclerosis: The Potential of Neurofilament Light Chain as a Biomarker of MS Activity, Progression

Using a novel...

For most of the authors is not an issue anymore if B-cells are the cause of MS. The question is how they produce MS. Here there is a fully available...

This is an article that I am reading slowly, as I do not understand most of the things it says. But the summary is that MS B-cells do weird things....

This is an article that I am reading slowly, as I do not understand most of the things it says. But the summary is that MS B-cells do weird things....

I get newsletters from a company I order food from and while they are all excellent, this current one discusses a subject of extreme importance when...

Development of biomarkers for multiple sclerosis as a neurodegenerative disorder

Abstract

Multiple sclerosis (MS) is the most common...

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Taurine Seen to Boost Effectiveness of MS Therapies in Remyelination Process, Study Shows

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The mrz reaction helps to distinguish rheumatologic disorders with central nervous involvement from multiple sclerosis

Abstract

Background...

Whatever simvastatin does in MS is independent from its cholesterol function

Abstract

The analysis of clinical trials is limited to...

US toddlers aged 19-23 months consume 7.1 teaspoons of added sugar per day.

Consumption of added sugars among U.S. infants aged 6-23 months,...

Frozen fruits and vegetables generally have less pesticide residue than fresh conventional produce.

And nutrition levels are about the same as...

Identification of candidate biomarkers in converting and non-converting clinically isolated syndrome by proteomics analysis of cerebrospinal fluid...

These people report four metabolic pathways altered in RRMS: glycerophospholipid, citrate cycle, sphingolipids, and pyruvate metabolism....

The consortium of multiple sclerosis centers has published an updated protocol as of 2018. As far as I can see, now they recommend advanced MRI...

Different clinical response to interferon beta and glatiramer acetate related to the presence of oligoclonal IgM bands in CSF in multiple sclerosis...

Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS

Abstract

Multiple sclerosis (MS) is an...

Diagnosis in MS is based in clinical finding. Usually all tests require to prove that there are lesions in the brain disseminated in time and space....

MRS (Magnetic Resonance Spectroscopy) can show the chemical composition of the brain. It seems that some chemical markers (the relationship of...