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2018 Editorial - Diet in MS: Science takes a seat...

Last post by jimmylegs « Sat Jun 02, 2018 5:54 pm
Posted in Diet

by jimmylegs » Sat Jun 02, 2018 5:54 pm » in Diet

well, look who's decided to join us ;)

Diet in multiple sclerosis: Science takes a seat at the table
author info:

Let food be your medicine and...

0 Replies

1022 Views

Last post by jimmylegs
Sat Jun 02, 2018 5:54 pm
personalized medicine for MS

Last post by frodo « Thu May 31, 2018 7:52 am
Posted in MS Etiology and Pathogenesis

by frodo » Thu May 31, 2018 7:52 am » in MS Etiology and Pathogenesis

Towards personalized therapy for multiple sclerosis: prediction of individual treatment response

Abstract

Timely initiation of effective therapy...

0 Replies

612 Views

Last post by frodo
Thu May 31, 2018 7:52 am
has anybody heard about Bryostatin?

Last post by frodo « Wed May 30, 2018 10:41 pm
Posted in General Discussion

by frodo » Wed May 30, 2018 10:41 pm » in General Discussion

It seems that it is a new drug on trials. Has anybody tried it?

Bryostatin-1 as a macrolide and marine natural product has been selected as a...

0 Replies

702 Views

Last post by frodo
Wed May 30, 2018 10:41 pm
choose your favorite explanation

Last post by frodo « Tue May 29, 2018 12:28 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue May 29, 2018 12:28 am » in MS Etiology and Pathogenesis

This is about the secondary progressive phase enigmas.

Anti-inflammatory drugs that reduce inflammatory (immune) attacks in patients with RRMS fail...

0 Replies

579 Views

Last post by frodo
Tue May 29, 2018 12:28 am
Progressive (and RR) trial seeking participants - EBV based

Last post by CureOrBust « Mon May 28, 2018 1:10 am
Posted in Drug Pipeline

by CureOrBust » Mon May 28, 2018 1:10 am » in Drug Pipeline

The following trial is currently enrolling for SP, PP and RR subjects. Its based off of the work by Prof Pender regarding EBV.

I know in Sydney...

0 Replies

1143 Views

Last post by CureOrBust
Mon May 28, 2018 1:10 am
2018 study: diet/disease correlation in EAE

Last post by jimmylegs « Sun May 27, 2018 3:58 am
Posted in Diet

by jimmylegs » Sun May 27, 2018 3:58 am » in Diet

Variations in diet cause alterations in microbiota and metabolites that follow changes in disease severity in a multiple sclerosis model

Multiple...

0 Replies

1354 Views

Last post by jimmylegs
Sun May 27, 2018 3:58 am
Cryotherapy thoughts?

Last post by orphansparrow « Sat May 26, 2018 8:33 am
Posted in Regimens

by orphansparrow » Sat May 26, 2018 8:33 am » in Regimens

Hi all.

Anyone here do cryotherapy? What is your experience/thoughts?

Thank you!

0 Replies

1741 Views

Last post by orphansparrow
Sat May 26, 2018 8:33 am
Cerebral Blood Flow Changes in Multiple Sclerosis

Last post by frodo « Thu May 24, 2018 8:47 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Thu May 24, 2018 8:47 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Cerebral Blood Flow Changes in Multiple Sclerosis and Neuromyelitis Optica and Their Correlations With Clinical Disability.

Abstract...

0 Replies

915 Views

Last post by frodo
Thu May 24, 2018 8:47 am
red blood cells have altered metabolism

Last post by frodo « Thu May 24, 2018 12:23 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Thu May 24, 2018 12:23 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

red blood cells have altered metabolism

Glucose transporter 1 (GLUT1) is the main glucose transporter on RBCs, and all metabolism within theRBC...

0 Replies

908 Views

Last post by frodo
Thu May 24, 2018 12:23 am
new biomarker linked to blood flow

Last post by frodo « Tue May 22, 2018 4:48 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Tue May 22, 2018 4:48 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Quote: The glycocalyx (GLX) is carbohydrate-rich outer surface of the blood vessel wall and is the first interaction between the blood and the...

0 Replies

948 Views

Last post by frodo
Tue May 22, 2018 4:48 am
impaired cerebral perfusion in MS

Last post by frodo « Tue May 22, 2018 4:35 am
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Tue May 22, 2018 4:35 am » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Long paper about general brain perfusion, but deals with MS at the end:

Extracted from the article:

Brain perfusion in MS

In patients with MS,...

0 Replies

873 Views

Last post by frodo
Tue May 22, 2018 4:35 am
Microbiome

Last post by NHE « Tue May 22, 2018 12:11 am
Posted in Humor

by NHE » Tue May 22, 2018 12:11 am » in Humor

The real microbiome...

0 Replies

881 Views

Last post by NHE
Tue May 22, 2018 12:11 am
Sera from MS patients disrupt the BBB

Last post by frodo « Thu May 17, 2018 9:46 pm
Posted in MS Etiology and Pathogenesis

by frodo » Thu May 17, 2018 9:46 pm » in MS Etiology and Pathogenesis

0 Replies

627 Views

Last post by frodo
Thu May 17, 2018 9:46 pm
DNA-binding factor TOX might trigger MS

Last post by crunkz « Thu May 17, 2018 11:31 am
Posted in MS Etiology and Pathogenesis

by crunkz » Thu May 17, 2018 11:31 am » in MS Etiology and Pathogenesis

Researchers at the University of Geneva (UNIGE), Switzerland, and Geneva University Hospitals (HUG) have identified a DNA-binding factor called TOX...

0 Replies

589 Views

Last post by crunkz
Thu May 17, 2018 11:31 am
Inside-out model: Axonal damage mechanisms in early MS

Last post by frodo « Thu May 17, 2018 1:55 am
Posted in MS Etiology and Pathogenesis

by frodo » Thu May 17, 2018 1:55 am » in MS Etiology and Pathogenesis

Early axonal damage in normal appearing white matter in multiple sclerosis: Novel insights from multi-shell diffusion MRI

Abstract :...

0 Replies

581 Views

Last post by frodo
Thu May 17, 2018 1:55 am
Quote of the day...

Last post by NHE « Thu May 17, 2018 1:26 am
Posted in Daily Life

by NHE » Thu May 17, 2018 1:26 am » in Daily Life

The reasonable man adapts himself to the world, the unreasonable one persists in trying to adapt the world to himself. Therefore, all progress...

0 Replies

842 Views

Last post by NHE
Thu May 17, 2018 1:26 am
Microglial activation and NAWM appear together

Last post by frodo « Thu May 17, 2018 1:13 am
Posted in MS Etiology and Pathogenesis

by frodo » Thu May 17, 2018 1:13 am » in MS Etiology and Pathogenesis

Microglial activation and NAWM appear together. A study found that microglial activation (shown by PET imaging) and Normal appearing white matter...

0 Replies

541 Views

Last post by frodo
Thu May 17, 2018 1:13 am
CCSVI angioplasty procedure ok to do unless called research

Last post by Cece « Sat May 12, 2018 5:18 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by Cece » Sat May 12, 2018 5:18 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

The FDA could intervene in the cases of Arata and McGuckin because they were calling their procedures research, over which the agency has...

0 Replies

956 Views

Last post by Cece
Sat May 12, 2018 5:18 pm
Activated FoxO3 blocks myelin production

Last post by crunkz « Thu May 10, 2018 4:53 pm
Posted in MS Etiology and Pathogenesis

by crunkz » Thu May 10, 2018 4:53 pm » in MS Etiology and Pathogenesis

Links:

Results showed that one specific-size fragment of Hialuronic Acid affected OPCs. Treating rat cells modeling white matter disease with...

0 Replies

639 Views

Last post by crunkz
Thu May 10, 2018 4:53 pm
RE:MS PATIENT CARLOS TESTIMONAL AFTER HAD FTM TREATMENT

Last post by seeva « Wed May 09, 2018 2:18 am
Posted in General Discussion

by seeva » Wed May 09, 2018 2:18 am » in General Discussion

HI FRENDS PLEASE WATCH THE CARLOS'S TESTIMONIAL VEDIOI

regards
seeva

0 Replies

742 Views

Last post by seeva
Wed May 09, 2018 2:18 am
Inside-out model: Altered myelin could trigger immune attack

Last post by frodo « Tue May 08, 2018 5:16 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue May 08, 2018 5:16 am » in MS Etiology and Pathogenesis

Biochemically altered myelin triggers autoimmune demyelination

Abstract

Although immune attack against central nervous system (CNS) myelin is a...

0 Replies

616 Views

Last post by frodo
Tue May 08, 2018 5:16 am
Diagnosis: Diffusion Tensor Imaging shows NAWM

Last post by frodo « Tue May 08, 2018 4:52 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue May 08, 2018 4:52 am » in MS Etiology and Pathogenesis

Role of MRI Diffusion Tensor Imaging in Assessment of Normal Appearing White Matter in Cases of Multiple Sclerosis.

Abstract:

Background:...

0 Replies

560 Views

Last post by frodo
Tue May 08, 2018 4:52 am
Biomarkers: Excesive yawning associated to MS

Last post by frodo « Tue May 08, 2018 4:49 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue May 08, 2018 4:49 am » in MS Etiology and Pathogenesis

Yawning and cortisol levels in multiple sclerosis: potential new diagnostic tool

Abstract

Yawning is a significant behavioural response and,...

0 Replies

533 Views

Last post by frodo
Tue May 08, 2018 4:49 am
Is Multiple Sclerosis Caused by the Jaw and Cranial Bones?

Last post by ANothingNobody « Mon May 07, 2018 12:21 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by ANothingNobody » Mon May 07, 2018 12:21 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Multiple Sclerosis (MS) is likely a biomechanical disease caused by the jaw muscles, cranial bones, and veins of the body. The autoimmune paradigm...

0 Replies

963 Views

Last post by ANothingNobody
Mon May 07, 2018 12:21 pm
What's Living in You?

Last post by NHE « Fri May 04, 2018 1:54 am
Posted in General Discussion

by NHE » Fri May 04, 2018 1:54 am » in General Discussion

Nova on PBS discusses the microbiome.

Watch it online...

What's Living in You?

0 Replies

675 Views

Last post by NHE
Fri May 04, 2018 1:54 am
Carlos: MS & FMT Treatment

Last post by seeva « Tue May 01, 2018 11:29 pm
Posted in Drug Pipeline

by seeva » Tue May 01, 2018 11:29 pm » in Drug Pipeline

HI FRIENDS GOOD INFO PLEASE READ

Meet Carlos, he was diagnosed with MS (Multiple sclerosis). He tells his story & his journey with FMT and how he...

0 Replies

992 Views

Last post by seeva
Tue May 01, 2018 11:29 pm
Wishing I could get answers

Last post by teachrlady « Tue May 01, 2018 8:08 am
Posted in Undiagnosed

by teachrlady » Tue May 01, 2018 8:08 am » in Undiagnosed

My symptoms started several years ago and I was tested for everything and eventually diagnosed with Fibromyalgia. Recently, started getting...

0 Replies

981 Views

Last post by teachrlady
Tue May 01, 2018 8:08 am
8 Ways to Attack Secondary Progressive MS

Last post by seeva « Tue May 01, 2018 3:52 am
Posted in Regimens

by seeva » Tue May 01, 2018 3:52 am » in Regimens

HI FRIENDS PLEASE READ

REGARDS
SEEVA

0 Replies

1050 Views

Last post by seeva
Tue May 01, 2018 3:52 am
Biomarkers: Biomarker to separate RRMS and progresive forms

Last post by frodo « Mon Apr 30, 2018 4:26 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Apr 30, 2018 4:26 am » in MS Etiology and Pathogenesis

Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing‐remitting MS

Abstract

Multiple sclerosis (MS) is...

0 Replies

673 Views

Last post by frodo
Mon Apr 30, 2018 4:26 am
NAWM is the beginning of MS and can be seen with special MRI

Last post by frodo « Sun Apr 29, 2018 11:19 pm
Posted in MS Etiology and Pathogenesis

by frodo » Sun Apr 29, 2018 11:19 pm » in MS Etiology and Pathogenesis

DTI (Diffusion Tensor Imaging MRI) shows the most early tissue injury in MS, when atrophy and lesions are not yet detectable (non lesional damage,...

0 Replies

583 Views

Last post by frodo
Sun Apr 29, 2018 11:19 pm
MS and ozone

Last post by koneall « Sun Apr 29, 2018 12:08 pm
Posted in General Discussion

by koneall » Sun Apr 29, 2018 12:08 pm » in General Discussion

I use ozone in my veterinary practice and I have MS so the idea of ozone treatment in Multiple Sclerosis is intriguing. I do personal DIV 20 gamma...

0 Replies

626 Views

Last post by koneall
Sun Apr 29, 2018 12:08 pm
klamath

Last post by zen2010 « Sat Apr 28, 2018 12:41 am
Posted in Natural Approach

by zen2010 » Sat Apr 28, 2018 12:41 am » in Natural Approach

Hi,

I recently heard about this dietary supplement which can help PWMS to get better.

Has anyone tried this?

Thks

0 Replies

783 Views

Last post by zen2010
Sat Apr 28, 2018 12:41 am
Ocrevus and Progressive MS Facebook group

Last post by undisclosED « Wed Apr 25, 2018 2:11 pm
Posted in Ocrevus (Ocrelizumab)

by undisclosED » Wed Apr 25, 2018 2:11 pm » in Ocrevus (Ocrelizumab)

If anyone is interested, there is a new, closed Facebook group that was started on April 13, 2018 specifically for PPMS, SPMS and Ocrevus.

0 Replies

1671 Views

Last post by undisclosED
Wed Apr 25, 2018 2:11 pm
Amazon struggles to stop fake reviews

Last post by NHE « Wed Apr 25, 2018 12:22 am
Posted in Shopping

by NHE » Wed Apr 25, 2018 12:22 am » in Shopping

An interesting article...

How merchants quietly use Facebook to flood Amazon with fake reviews

0 Replies

2340 Views

Last post by NHE
Wed Apr 25, 2018 12:22 am
Biomarkers: Remains of a retrovirus in blood as biomarker

Last post by frodo « Tue Apr 24, 2018 11:27 pm
Posted in MS Etiology and Pathogenesis

by frodo » Tue Apr 24, 2018 11:27 pm » in MS Etiology and Pathogenesis

Clinical profile of a new serum biomarker as a potential product of endogenous human retroviral protein degradation in patients with multiple...

0 Replies

618 Views

Last post by frodo
Tue Apr 24, 2018 11:27 pm
Biomarkers: Distinction between RRMS and PMS

Last post by frodo « Tue Apr 24, 2018 11:24 pm
Posted in MS Etiology and Pathogenesis

by frodo » Tue Apr 24, 2018 11:24 pm » in MS Etiology and Pathogenesis

They do not say wether they refer to primary-progressive or SPMS

Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from...

0 Replies

597 Views

Last post by frodo
Tue Apr 24, 2018 11:24 pm
Pathogenic distinction between PP and SPMS still debated

Last post by frodo « Mon Apr 23, 2018 5:18 am
Posted in MS Etiology and Pathogenesis

by frodo » Mon Apr 23, 2018 5:18 am » in MS Etiology and Pathogenesis

It seems that PPMS and SPMS courses are different.

Demyelination and Neurodegeneration along the Visual Pathway are more prominent in Secondary...

0 Replies

596 Views

Last post by frodo
Mon Apr 23, 2018 5:18 am
MitoQ: Adverse Effects

Last post by NHE « Sun Apr 22, 2018 4:25 pm
Posted in Natural Approach

by NHE » Sun Apr 22, 2018 4:25 pm » in Natural Approach

The targeted anti-oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue.
Physiol Rep. 2018 Apr;6(7):e13667.

Kidney...

0 Replies

819 Views

Last post by NHE
Sun Apr 22, 2018 4:25 pm
GUT GERMS APPEAR TO PLAY ROLE IN M.S

Last post by seeva « Sat Apr 21, 2018 6:20 pm
Posted in Regimens

by seeva » Sat Apr 21, 2018 6:20 pm » in Regimens

DEAR FRIENDS PLEASE READ

regards
seeva

0 Replies

1123 Views

Last post by seeva
Sat Apr 21, 2018 6:20 pm
Angiogenesis, fingolimod and ceramides

Last post by frodo « Thu Apr 19, 2018 11:19 pm
Posted in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

by frodo » Thu Apr 19, 2018 11:19 pm » in Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Recently I am finding some connections that I would like to share.

First of all, Fingolimod is a known active principle, an immune-modulator, which...

0 Replies

1049 Views

Last post by frodo
Thu Apr 19, 2018 11:19 pm
Biomarkers. MS signature found in CSF

Last post by frodo « Thu Apr 19, 2018 10:04 pm
Posted in MS Etiology and Pathogenesis

by frodo » Thu Apr 19, 2018 10:04 pm » in MS Etiology and Pathogenesis

Enhanced release of acid sphingomyelinase-enriched exosomes generates a lipidomics signature in CSF of Multiple Sclerosis patients

Abstract...

0 Replies

647 Views

Last post by frodo
Thu Apr 19, 2018 10:04 pm
Biomarkers. Response to Fingolimod can be predicted.

Last post by frodo « Thu Apr 19, 2018 12:31 pm
Posted in MS Etiology and Pathogenesis

by frodo » Thu Apr 19, 2018 12:31 pm » in MS Etiology and Pathogenesis

Predicting therapeutic response to fingolimod treatment in multiple sclerosis patients

Summary

Fingolimod, an orally active immunomodulatory...

0 Replies

589 Views

Last post by frodo
Thu Apr 19, 2018 12:31 pm
PPMS: Two different subtypes set appart by fluid biomarkers

Last post by frodo « Wed Apr 18, 2018 9:51 am
Posted in MS Etiology and Pathogenesis

by frodo » Wed Apr 18, 2018 9:51 am » in MS Etiology and Pathogenesis

Transcriptional profiling of Primary Progressive Multiple Sclerosis patients identifies Fast and Slow progression patterns (P1.321)

Abstract...

0 Replies

605 Views

Last post by frodo
Wed Apr 18, 2018 9:51 am
TOUCHED BY THE LORD'S HAND:: THE HISTRY OF M.S

Last post by seeva « Tue Apr 17, 2018 5:26 pm
Posted in Introductions

by seeva » Tue Apr 17, 2018 5:26 pm » in Introductions

HI FRIENDS PLEASE READ

regards
seeva

0 Replies

1212 Views

Last post by seeva
Tue Apr 17, 2018 5:26 pm
A model of de-myelination for multiple sclerosis

Last post by gristy56 « Mon Apr 16, 2018 1:03 am
Posted in General Discussion

by gristy56 » Mon Apr 16, 2018 1:03 am » in General Discussion

A model of de-myelination, as it really is.
By Simon Ewart-Grist

For this demonstration you need -

1. A supply of ordinary round party balloons.
2....

0 Replies

703 Views

Last post by gristy56
Mon Apr 16, 2018 1:03 am
who's on twitter

Last post by jimmylegs « Sat Apr 14, 2018 8:20 am
Posted in General Discussion

by jimmylegs » Sat Apr 14, 2018 8:20 am » in General Discussion

interesting new campaign #thisisms

0 Replies

610 Views

Last post by jimmylegs
Sat Apr 14, 2018 8:20 am
CCSVI: Angioplasty could work in a subgroup of patients

Last post by frodo « Wed Apr 11, 2018 6:45 am
Posted in MS Etiology and Pathogenesis

by frodo » Wed Apr 11, 2018 6:45 am » in MS Etiology and Pathogenesis

Chronic Cerebro-Spinal Venous Insufficiency in Multiple Sclerosis: Is It the End?

It was published the long awaited Italian clinical trial...

0 Replies

680 Views

Last post by frodo
Wed Apr 11, 2018 6:45 am
Progressive MS: Review of medications

Last post by frodo « Wed Apr 11, 2018 6:40 am
Posted in MS Etiology and Pathogenesis

by frodo » Wed Apr 11, 2018 6:40 am » in MS Etiology and Pathogenesis

Interesting this article. They acklowledge that It remains a challenge to identify outcome measures that accurately reflect the underlying pathology...

0 Replies

627 Views

Last post by frodo
Wed Apr 11, 2018 6:40 am
MS and APS and PD

Last post by koneall « Thu Apr 05, 2018 8:05 am
Posted in General Discussion

by koneall » Thu Apr 05, 2018 8:05 am » in General Discussion

Ten months ago I was dx'd with multiple sclerosis and subsequently antiphospholipid syndrome and then Parkinson's Disease. For APS there are three...

0 Replies

660 Views

Last post by koneall
Thu Apr 05, 2018 8:05 am
Type II pattern impressively responsive to alemtuzumab

Last post by frodo « Tue Apr 03, 2018 4:51 am
Posted in MS Etiology and Pathogenesis

by frodo » Tue Apr 03, 2018 4:51 am » in MS Etiology and Pathogenesis

They openly speak about a B-cell driven multiple sclerosis for the first time, and they identify it to the pattern II.

Rescue therapy with...

0 Replies

763 Views

Last post by frodo
Tue Apr 03, 2018 4:51 am

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