I also notice that under-eating causes greater spasticity.
What's going on here?
Trying to lose weight to feel and be better. But I actually feel worse. What’s a mother to do?
I am basically doing Weight Watchers program...I did it successfully in the past before I was dx’d with MS.
I asked my primary care physician about this. His recommendation was to make sure I spread my eating out evenly through the day. I already do that.. so no help.
So we stay on topic we’re just talking about fatigue and diet, nothing else.
There are a couple of things related to fatigue but I will try to make it as straightforward as I can.
Energy is driven by our ability to make a molecule called ATP (adenosine triphosphate). We make it and use it in every process in the body. The ability to make it is limited by the pathways involved and the ability to access the building blocks involved. Some steps are quick and some are quite slow.
The issue is ATP isn’t stored, it’s made on demand. There isn’t a lot of it at any one time. If you stopped making it your heart cells would have none left after 10 heartbeats so it’s critical to have the ingredients always available.
The bulk of ATP is provided through a chain of steps inside part of the cell called the mitochondria. These steps involve passing electrons donated by fatty acids down a series of complexes called the electron transport chain to a tiny machine called ATPase where new ATP is made.
If you have fatigue then this process needs a hand. You have to get fatty acids, you have to get electrons into the mitochondria and you have to get ATP out of the mitochondria.
The fatty acids come from food. As this is a simple explanation you can look up sources of fatty acids. Sugar is not going to donate the electron. That’s a different process. You need fatty acids but you don’t need refined sugar at all.
There are many types of sugar but just refined sugar hits the body too rapidly. It gives a short term high but it does not add anything to making ATP. Refined sugar overwhelms the body’s processes. It makes the body rapidly deal with a sudden sugar surge and promotes the conversion of surplus sugar into blubber to be drawn on in famine. Our global problem of obesity and diabetes is all about this.
The membrane around mitochondria is practically impenetrable. The electrons can’t get in unless they hitch a ride on a substance that can readily cross from outside to inside. The best molecule is called carnitine. The process is called the carnitine shuttle.
The electron is transferred by a molecule called Coenzyme Q10. It works because it can both donate and accept electrons. Most molecules can’t do both.
If you take CoQ10 and carnitine in the form acetyl-l-carnitine you can rebuild your capacity to make ATP.
Try to find brands that have the ingredients listed as detailed in the ingredients on the products which I take - https://www.bioceuticals.com.au/product ... xcel-150mg and http://www.hygiology.com.au/Acetyl-L-Carnitine/p=690/ . Practitioner quality brands ensure good laboratory practice. That’s essential or you risk buying lollies.
When you make ATP you want it to be stable so add magnesium to your diet. I use this one http://www.chemistwarehouse.com.au/buy/ ... 20-Tablets
If your diet includes added sugar try changing it. That includes breakfast and packaged food.
As a last thing, your doctor may have put you on a statin. If he has then, you have knocked out the pathway that make CoQ10 and you will be struggling. You need CoQ10 supplements regardless if this has happened.
Hope that helps and you can follow it.
I'm not sure I know what under eating really means. Some people swear by fasting.
Have you been checked for Diabetes Insipidus? It's not the normal diabetes so don't jump the gun.
Have a look at this- https://www.betterhealth.vic.gov.au/hea ... -insipidus
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