Science Pinpoints Nutrients Crucial to Brain Health

[ElliotB]

I found this interesting article about brain nutrition.

https://www.usnews.com/news/health-news ... ain-health


Yet, as is often the case, the article is somewhat incomplete. Once supplement in particular that is considered highly important for brain health that most have likely never heard of is Phosphatidylserine. What Is Phosphatidylserine? The link below is to a pretty good article about Phosphatidylserine and worth using to find out. I have been taking this supplement for many years...

https://www.usnews.com/news/health-news ... ain-health

[DIM]

I give to my wife 3 caps per day Phosphatidylserine since the first days of her MS along with Q10, ALA, AlCar, Omega 3!
Later we added lots of supplements that help too

[ElliotB]

@DIM

I am taking all of the supplements you take, and many others as well. Great choices!

Do you feel the supplements have helped her? I feel they have really helped me. My memory is excellent now and has been for many years after starting the supplements, far better than at any time prior to my diagnosis. Even as a child, my memory was poor.

What kind of diet is she following?

[DIM]

She is on a lactose - gluten free diet and with no food that has intolerance to, according to her ELISA test.
A Mediterranean like diet but reach in proteins and cholesterol/healthy fats.
Her blood tests are much better than before her MS, and the supplements, especially when she takes many antioxidants together, help her too much!
Imagine sometimes the evenings has gait problem and when takes the supplements can walk enough distance after 1/2-1 hour.
She walks on treadmill ~15 mins the morning and exercises 30 mins on Power plate 5 times/week each evening.

PS: I don't think you could take more supplements:
Inosine, NAC, Na-R-ALA, Q10, EPA/DHA, Probiotics (500 trillion) + Saccharomyces Boulardi + Tryptophan, Zinc, ASC2P (vit C), Niacin, Tocotrienols+Vit E, Vit A, Chromium, Selenium, D3+K2, Cal+Mag + MagTein, Iron, B complex coenzymated, B1 coenzymated, CurQfen (Curcumin), Ginkgo, Siliphos (milk thistle), CDP Choline, EGCG liposomal, Quercetin liposomal, Phosphatidyl serine, Apigenin liposomal, Olive leaf extract, Andrographis Paniculata, ALCAR (carnitine), Monolaurin...hope I didn't forget something!

[NHE]

Here's the original journal article.

Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study
NPJ Aging. 2024 May 21;10(1):27

The emerging field of Nutritional Cognitive Neuroscience aims to uncover specific foods and nutrients that promote healthy brain aging. Central to this effort is the discovery of nutrient profiles that can be targeted in nutritional interventions designed to promote brain health with respect to multimodal neuroimaging measures of brain structure, function, and metabolism. The present study therefore conducted one of the largest and most comprehensive nutrient biomarker studies examining multimodal neuroimaging measures of brain health within a sample of 100 older adults. To assess brain health, a comprehensive battery of well-established cognitive and brain imaging measures was administered, along with 13 blood-based biomarkers of diet and nutrition. The findings of this study revealed distinct patterns of aging, categorized into two phenotypes of brain health based on hierarchical clustering. One phenotype demonstrated an accelerated rate of aging, while the other exhibited slower-than-expected aging. A t-test analysis of dietary biomarkers that distinguished these phenotypes revealed a nutrient profile with higher concentrations of specific fatty acids, antioxidants, and vitamins. Study participants with this nutrient profile demonstrated better cognitive scores and delayed brain aging, as determined by a t-test of the means. Notably, participant characteristics such as demographics, fitness levels, and anthropometrics did not account for the observed differences in brain aging. Therefore, the nutrient pattern identified by the present study motivates the design of neuroscience-guided dietary interventions to promote healthy brain aging.

Free full text.

[ElliotB]

@Dim

I am also on a gluten free diet and am pretty much lactose free as well although I do consume a small amount of specific European cheese (genuine Parmigiano Reggiano cheese). Although I reside in the USA, I will not consume any type of dairy products from American cows.

With regards to the supplements, I take pretty much all of the ones you provided in your 2nd list, and then believe it or not a lot more!

I too am healthier now than prior to my MS diagnosis since I changed my diet and started taking supplements about 10 years ago. My MS has not progressed at all, no attacks, most of my symptoms have gone, I have not been sick in any way - I have not even had a single cold, flu, covid or any other illness since I made these changes in my diet.

So happy to hear your wife is doing well!

[ElliotB]

This video clearly explains the issues with dairy products from the USA that come from cows. Buffalo and goat dairy products are unaffected.

The issue has to do with a protein called Casein a1. Even as a child, I had issues with dairy. Now the only dairy products I consume are from outside the US, or goat's milk. Have not tried Buffalo cheese yet but plan to - apparently Buffalo Mozzarella is delicious!

[DIM]

Unfortunately even in Europe most cows are the same breed as US cows, the best choice is organic goat yogurt or cheese, from grassfed animals.
Fortunately we personally have access to game meet along with organic, antibiotic-free domestic poultry etc!

[ElliotB]

Thanks for the head up. I have had and enjoyed goat cheese very much and am now going to try buffalo cheese.

[DIM]

We eat buffalo liver twice/week, wild boar, hare and poultry meats.
I personally eat lots of cheese and kefir though as I am training daily, but I realized that I too have some kind of intolerance to cow milk more than any other dairy product.

[DIM]

New Study Uncovers Cholesterol's Role in Worsening Multiple Sclerosis
Research reveals how statins may protect brain cells and slow disease progression, offering hope for new treatment strategies

https://news.cuanschutz.edu/news-storie ... -sclerosis

[Jaded]

So Dr Swank was right all along

[NHE]

So Dr Swank was right all along

I thought the Swank diet was about reducing saturated fat? Isn't cholesterol a different issue?

[DIM]

So Dr Swank was right all along

I thought the Swank diet was about reducing saturated fat? Isn't cholesterol a different issue?

Even cholesterol isn't bad, there are many cholesterol molecules except the HDL-LDL that are far more important for our health.
Last days I read contradictive trials about cholesterol and brain health, I think the magic word here is balance.
A healthy diet with lots of good fats (Ω3), lots of proteins (body needs them to fight EBV among others), vegetables, and some fruits and nuts, can not be bad for brain health imho!

[NHE]

Brain fog, as well as muscle pain, are common side effects for people taking statins. There are others as well such as an increased risk for cataracts.

Please refer to the posts in the statin forum.

viewforum.php?f=33